There are 10 ways to get from Mainz to Lisse by train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Frankfurt Flughafen Fernb to Utrecht Centraaltrain Ice
5h 49m€53–160Bus
- Take the bus from Frankfurt central train station to Amsterdam Sloterdijkbus N61 / ...
9h 32m€53–78Drive 445.3 km
- Drive from Mainz to Lissecar 445.3 km
4h 27m€93–134Fly Frankfurt to Amsterdam Airport Schiphol
- Fly from Frankfurt (FRA) to Amsterdam Airport Schiphol (AMS)plane FRA - AMS
4h 28m€119–300Train via Arnhem
- Take the train from Frankfurt to Arnhem Centraaltrain 78 / ...
- Take the train from Arnhem Centraal to Schiphol Airport Train Stationtrain Intercity
6h 7m€55–160Train #2
- Take the train from Mainz, Hauptbahnhof to Utrecht Centraaltrain 43N
- Take the train from Utrecht Centraal to Schiphol Airport Train Stationtrain Intercity / ...
6h 38m€54–155Train via Cologne
- Take the train from Mainz, Hauptbahnhof to Köln Hbftrain 91 / ...
- Take the train from Köln Hbf to Utrecht Centraaltrain Ice
- Take the train from Utrecht Centraal to Sassenheimtrain
7h 8m€66–156Train to Düsseldorf International Airport, fly to Amsterdam Airport Schiphol
- Take the train from Frankfurt to Düsseldorf Hbftrain
- Fly from Düsseldorf International Airport (DUS) to Amsterdam Airport Schiphol (AMS)plane DUS - AMS
5h 21m€172–432Fly Frankfurt to Düsseldorf International Airport, train
- Fly from Frankfurt (FRA) to Düsseldorf International Airport (DUS)plane FRA - DUS
- Take the train from Düsseldorf Hbf to Arnhem Centraaltrain
- Take the train from Arnhem Centraal to Schiphol Airport Train Stationtrain
6h 30m€129–207Fly Frankfurt to Brussels Airport, train, line 361 bus
- Fly from Frankfurt (FRA) to Brussels Airport (BRU)plane FRA - BRU
- Take the train from Anvers-Central to Schiphol Airporttrain
- Take the bus from Schiphol, Airport/Plaza to Lisse, Centrumbus
6h 33m€115–313
Mainz to Lisse by train and bus
Comparing Your Travel Options
The cheapest way to get from Mainz to Lisse is to bus which costs €50 - €80 and takes 9h 32m.
The fastest way to get from Mainz to Lisse is to drive which takes 4h 27m and costs €90 - €140.
No, there is no direct bus from Mainz station to Lisse. However, there are services departing from Mainz central train station and arriving at Lisse, Centrum via Frankfurt central train station, Amsterdam, Station Sloterdijk and Schiphol, Airport/Plaza. The journey, including transfers, takes approximately 9h 32m.
No, there is no direct train from Mainz to Lisse. However, there are services departing from Mainz, Römisches Theater and arriving at Sassenheim via Frankfurt Flughafen Fernb, Utrecht Centraal and Amsterdam Zuid. The journey, including transfers, takes approximately 5h 49m.
The distance between Mainz and Lisse is 487 km. The road distance is 445.3 km.
The best way to get from Mainz to Lisse without a car is to train which takes 5h 49m and costs €50 - €160.
It takes approximately 5h 49m to get from Mainz to Lisse, including transfers.
Mainz to Lisse bus services, operated by FlixBus, depart from Frankfurt central train station.
Mainz to Lisse train services, operated by Nederlandse Spoorwegen (NS), depart from Frankfurt Flughafen Fernb station.
The best way to get from Mainz to Lisse is to train which takes 5h 49m and costs €50 - €160. Alternatively, you can bus, which costs €50 - €80 and takes 9h 32m, you could also fly, which costs €110 - €300 and takes 4h 28m.
What companies run services between Mainz, Germany and Lisse, Netherlands?
Nederlandse Spoorwegen (NS) operates a train from Frankfurt Flughafen Fernb to Utrecht Centraal every 4 hours. Tickets cost €40–80 and the journey takes 3h 11m. Deutsche Bahn Intercity (DB IC) also services this route every 3 hours. Alternatively, FlixBus operates a bus from Frankfurt central train station to Amsterdam Sloterdijk hourly. Tickets cost €40–60 and the journey takes 6h 10m.
- Website
- lufthansa.com
Flights from Frankfurt to Amsterdam Airport Schiphol
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €35–290
Flights from Frankfurt to Düsseldorf International Airport
- Ave. Duration
- 45 min
- When
- Every day
- Estimated price
- €30–240
Flights from Frankfurt to Brussels Airport
- Ave. Duration
- 1h 3m
- When
- Every day
- Estimated price
- €35–260
- Website
- klm.com
Flights from Frankfurt to Amsterdam Airport Schiphol
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €35–270
Flights from Düsseldorf International Airport to Amsterdam Airport Schiphol
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- €35–270
- Website
- brusselsairlines.com
Flights from Frankfurt to Brussels Airport
- Ave. Duration
- 1h 4m
- When
- Every day
- Estimated price
- €75–120
- Website
- lufthansa-city.com
Flights from Frankfurt to Amsterdam Airport Schiphol
- Ave. Duration
- 1h 15m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €35–270
Flights from Frankfurt to Düsseldorf International Airport
- Ave. Duration
- 45 min
- When
- Monday, Friday, and Sunday
- Estimated price
- €30–240
Flights from Frankfurt to Brussels Airport
- Ave. Duration
- 1h
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €35–260
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt Flughafen Fernb to Utrecht Centraal
- Ave. Duration
- 3h 11m
- Frequency
- Every 4 hours
- Estimated price
- €40–80
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Arnhem Centraal
- Ave. Duration
- 2h 38m
- Frequency
- Every 4 hours
- Estimated price
- €35–70
- Website
- Nederlandse Spoorwegen (NS)
Train from Arnhem Centraal to Schiphol Airport Train Station
- Ave. Duration
- 1h 9m
- Frequency
- Every 30 minutes
- Estimated price
- €11–20
- Website
- Nederlandse Spoorwegen (NS)
Train from Mainz, Hauptbahnhof to Utrecht Centraal
- Ave. Duration
- 4h 40m
- Frequency
- Twice a week
- Estimated price
- €40–80
- Website
- Nederlandse Spoorwegen (NS)
Train from Utrecht Centraal to Schiphol Airport Train Station
- Ave. Duration
- 32 min
- Frequency
- Every 15 minutes
- Estimated price
- €4–9
- Website
- Nederlandse Spoorwegen (NS)
Train from Köln Hbf to Utrecht Centraal
- Ave. Duration
- 2h 10m
- Frequency
- Every 4 hours
- Estimated price
- €24–45
- Website
- Nederlandse Spoorwegen (NS)
Train from Utrecht Centraal to Sassenheim
- Ave. Duration
- 1h 23m
- Frequency
- Hourly
- Estimated price
- €8–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Düsseldorf Hbf
- Ave. Duration
- 1h 22m
- Frequency
- Every 4 hours
- Estimated price
- €22–45
- Website
- Nederlandse Spoorwegen (NS)
Train from Düsseldorf Hbf to Arnhem Centraal
- Ave. Duration
- 1h 14m
- Frequency
- Every 4 hours
- Estimated price
- €13–25
- Website
- Nederlandse Spoorwegen (NS)
Train from Arnhem Centraal to Schiphol Airport Train Station
- Ave. Duration
- 1h 9m
- Frequency
- Every 30 minutes
- Estimated price
- €11–20
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt Flughafen Fernb to Utrecht Centraal
- Ave. Duration
- 3h 37m
- Frequency
- Every 3 hours
- Estimated price
- €60–130
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Arnhem Centraal
- Ave. Duration
- 2h 40m
- Frequency
- Every 3 hours
- Estimated price
- €50–120
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Utrecht Centraal
- Ave. Duration
- 5h 4m
- Frequency
- Twice daily
- Estimated price
- €65–140
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Köln Hbf
- Ave. Duration
- 1h 46m
- Frequency
- Every 2 hours
- Estimated price
- €29–65
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Köln Hbf to Utrecht Centraal
- Ave. Duration
- 2h 34m
- Frequency
- Every 4 hours
- Estimated price
- €35–75
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Düsseldorf Hbf
- Ave. Duration
- 1h 24m
- Frequency
- Hourly
- Estimated price
- €30–70
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Düsseldorf Hbf to Arnhem Centraal
- Ave. Duration
- 1h 15m
- Frequency
- Every 3 hours
- Estimated price
- €20–45
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- 0800-0232 545
- Website
- Arriva NL
Train from Utrecht Centraal to Schiphol Airport Train Station
- Ave. Duration
- 42 min
- Frequency
- Once a week
- Estimated price
- €8–13
- Website
- Arriva NL
- Second Class Single
- €8–13
- Phone
- +49-261-98887070
- service@trans-regio.de
- Website
- Trans Regio Deutsche Regionalbahn GmbH (MittelrheinBahn)
Train from Mainz, Hauptbahnhof to Köln Hbf
- Ave. Duration
- 3h
- Frequency
- Hourly
- Estimated price
- €30–45
- Schedules at
- Trans Regio Deutsche Regionalbahn GmbH (MittelrheinBahn)
- Phone
- +49 6078 966930
- service@vias-online.eu
- Website
- VIAS Rail GmbH
Train from Düsseldorf Hbf to Arnhem Centraal
- Ave. Duration
- 1h 48m
- Frequency
- Hourly
- Estimated price
- €42
- Schedules at
- VIAS Rail GmbH
- Phone
- +44 (0)3432 186 186
- Website
- Eurostar
Train from Anvers-Central to Schiphol Airport
- Ave. Duration
- 1h 3m
- Frequency
- Hourly
- Estimated price
- €55–90
- Website
- Eurostar
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Anvers-Central to Schiphol Airport
- Ave. Duration
- 1h 3m
- Frequency
- Every 3 hours
- Estimated price
- €27–45
- Website
- Belgian Railways
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Frankfurt central train station to Amsterdam Sloterdijk
- Ave. Duration
- 6h 10m
- Frequency
- Hourly
- Estimated price
- €40–60
- Website
- Flixbus
- Phone
- +31 900 0155
- Website
- Qbuzz B.V.
Bus from Schiphol, Airport/Plaza to Lisse, Centrum
- Ave. Duration
- 30 min
- Frequency
- Hourly
- Estimated price
- €6–8
- Website
- Qbuzz B.V.
Want to know more about travelling around Netherlands
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Mainz to Lisse bus services, operated by FlixBus, arrive at Amsterdam Sloterdijk station.
Mainz to Lisse train services, operated by Nederlandse Spoorwegen (NS), arrive at Utrecht Centraal station.
Yes, the driving distance between Mainz to Lisse is 445 km. It takes approximately 4h 27m to drive from Mainz to Lisse.
There are 1582+ hotels available in Lisse.






































