There are 12 ways to get from Mainz to Brno by train, bus, night train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Frankfurt to München Hbftrain 41 / ...
- Take the train from München Hbf to Salzburg Hauptbahnhoftrain 90 / ...
- Take the train from Salzburg Hbf to Wien Hbftrain Rjx / ...
- Take the train from Wien Hbf to Brno Hlavni Nadrazitrain Rj / ...
11h 10mKč 2,598–12,752Bus via Prague
cheapest- Take the bus from Mainz central train station to Praguebus N1310
- Take the bus from Praha, Hlavní Nádraží to Brnobus 260 / ...
12hKč 1,333–2,191Night train, train
- Take the night train from Frankfurt(Main)Sued to Praha Hlavni Nadrazinighttrain En
- Take the train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazitrain Rj / ...
13h 41mKč 3,865–8,816Drive 743.5 km
- Drive from Mainz to Brnocar 743.5 km
6h 17mKč 2,801–4,046Bus
- Take the bus from Frankfurt, Hauptbahnhof FOB to Brno Hlavní Nádražíbus Ivano-Frankivsk
21h 5mFly Frankfurt to Václav Havel Airport Prague, train
- Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)plane FRA - PRG
- Take the train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazitrain
7hKč 1,946–7,082Fly Frankfurt to Vienna International Airport, train
- Fly from Frankfurt (FRA) to Vienna International Airport (VIE)plane FRA - VIE
- Take the train from Wien Hbf to Brno Hlavni Nadrazitrain
6h 42mKč 1,988–5,302Fly Frankfurt to Salzburg Airport, train
- Fly from Frankfurt (FRA) to Salzburg Airport (SZG)plane FRA - SZG
- Take the train from Salzburg Hbf to Wien Hbftrain
- Take the train from Wien Hbf to Brno Hlavni Nadrazitrain
8hKč 4,448–12,432Train, train to Stuttgart Airport, fly to Vienna International Airport
- Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain
- Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Vienna International Airport (VIE)plane STR - VIE
- Take the train from Wien Hbf to Brno Hlavni Nadrazitrain
8h 24mKč 2,618–8,541Train to Cologne Bonn Airport, fly to Vienna International Airport, train
- Take the train from Frankfurt to Siegburg Bftrain
- Fly from Cologne Bonn Airport (CGN) to Vienna International Airport (VIE)plane CGN - VIE
- Take the train from Wien Hbf to Brno Hlavni Nadrazitrain
8h 52mKč 2,243–8,322Fly Frankfurt to Wroclaw, train
- Fly from Frankfurt (FRA) to Wroclaw (WRO)plane FRA - WRO
- Take the train from Wroclaw Glowny to Usti Nad Orlicitrain
- Take the train from Usti Nad Orlici to Brno Hlavni Nadrazitrain
10h 7mKč 3,298–8,432Fly Frankfurt to Linz Airport, train
- Fly from Frankfurt (FRA) to Linz Airport (LNZ)plane FRA - LNZ
- Take the train from Linz Hbf to Wien Hbftrain
- Take the train from Wien Hbf to Brno Hlavni Nadrazitrain
8h 48mKč 3,150–8,764
Mainz to Brno by train
Questions & Answers
The cheapest way to get from Mainz to Brno is to bus via Prague which costs 1 300 Kč - 2 200 Kč and takes 12h.
The fastest way to get from Mainz to Brno is to drive which takes 6h 17m and costs 2 800 Kč - 4 100 Kč.
No, there is no direct bus from Mainz station to Brno. However, there are services departing from Mainz central train station and arriving at Brno via Praha, Hlavní Nádraží. The journey, including transfers, takes approximately 12h.
No, there is no direct train from Mainz to Brno. However, there are services departing from Mainz, Römisches Theater and arriving at Brno Hlavni Nadrazi via Frankfurt, München Hbf, Salzburg Hbf and Wien Hbf. The journey, including transfers, takes approximately 11h 10m.
The distance between Mainz and Brno is 1036 km. The road distance is 743.5 km.
The best way to get from Mainz to Brno without a car is to train which takes 11h 10m and costs 2 600 Kč - 13 000 Kč.
It takes approximately 11h 10m to get from Mainz to Brno, including transfers.
Mainz to Brno bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Brno train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
The best way to get from Mainz to Brno is to train which takes 11h 10m and costs 2 600 Kč - 13 000 Kč. Alternatively, you can bus via Prague, which costs 1 300 Kč - 2 200 Kč and takes 12h.
What companies run services between Mainz, Germany and Brno, Czechia?
You can take a train from Mainz, Römisches Theater to Brno Hlavni Nadrazi via Frankfurt, München Hbf, Salzburg Hauptbahnhof, Salzburg Hbf, and Wien Hbf in around 11h 10m. Alternatively, you can take a bus from Mainz central train station to Brno via Prague and Praha, Hlavní Nádraží in around 12h.
- Website
- lufthansa.com
Flights from Frankfurt to Václav Havel Airport Prague
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- Kč 1,400–13,000
Flights from Frankfurt to Václav Havel Airport Prague via Munich
- Ave. Duration
- 2h 53m
- When
- Every day
- Estimated price
- Kč 1,400–7,500
Flights from Frankfurt to Vienna International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- Kč 1,800–4,300
Flights from Frankfurt to Salzburg Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- Kč 2,400–8,000
Flights from Stuttgart Airport to Vienna International Airport via Munich
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- Kč 2,000–2,800
Flights from Cologne Bonn Airport to Vienna International Airport via Munich
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- Kč 2,100–8,500
Flights from Frankfurt to Wroclaw
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- Kč 2,200–7,500
Flights from Frankfurt to Wroclaw via Munich
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- Kč 2,300–6,000
Flights from Frankfurt to Linz Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- Kč 2,200–3,100
- Website
- austrian.com
Flights from Frankfurt to Vienna International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- Kč 1,800–4,300
Flights from Frankfurt to Salzburg Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- Kč 2,400–8,000
Flights from Stuttgart Airport to Vienna International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- Kč 1,700–4,500
Flights from Cologne Bonn Airport to Vienna International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- Kč 1,300–4,900
- Website
- condor.com
Flights from Frankfurt to Václav Havel Airport Prague
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- Kč 1,400–3,800
Flights from Frankfurt to Vienna International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- Kč 1,600–3,700
- Website
- eurowings.com
Flights from Stuttgart Airport to Vienna International Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- Kč 1,700–4,500
Flights from Cologne Bonn Airport to Vienna International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- Kč 1,300–4,700
- Website
- lot.com
Flights from Frankfurt to Wroclaw
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- Kč 2,200–7,500
Flights from Frankfurt to Wroclaw via Warsaw Chopin
- Ave. Duration
- 3h 42m
- When
- Every day
- Estimated price
- Kč 2,300–6,500
- Website
- dat.dk
Flights from Frankfurt to Linz Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- Kč 2,200–3,100
- Website
- airdolomiti.it
Flights from Frankfurt to Václav Havel Airport Prague
- Ave. Duration
- 1h 5m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- Kč 2,600–13,000
Flights from Frankfurt to Wroclaw
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- Kč 2,200–7,500
- Website
- swiss.com
Flights from Stuttgart Airport to Vienna International Airport via Zurich
- Ave. Duration
- 2h 55m
- When
- Monday to Friday
- Estimated price
- Kč 2,000–2,800
Flights from Cologne Bonn Airport to Vienna International Airport via Zurich
- Ave. Duration
- 3h 50m
- When
- Monday to Saturday
- Estimated price
- Kč 1,600–4,900
- Website
- ryanair.com
Flights from Cologne Bonn Airport to Vienna International Airport
- Ave. Duration
- 1h 30m
- When
- Monday, Tuesday, Thursday, and Sunday
- Estimated price
- Kč 1,300–4,400
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Frankfurt to München Hbf
- Ave. Duration
- 3h 31m
- Frequency
- Hourly
- Estimated price
- Kč 1,800–5,500
- Website
- https://int.bahn.de/en
Train from München Hbf to Salzburg Hauptbahnhof
- Ave. Duration
- 1h 31m
- Frequency
- Hourly
- Estimated price
- Kč 650–1,900
- Website
- https://int.bahn.de/en
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Every 2 hours
- Estimated price
- Kč 310–900
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 38 min
- Frequency
- Every 30 minutes
- Estimated price
- Kč 470–1,400
- Website
- https://int.bahn.de/en
Train from Frankfurt to Siegburg Bf
- Ave. Duration
- 57 min
- Frequency
- Hourly
- Estimated price
- Kč 600–1,900
- Website
- https://int.bahn.de/en
Train from Linz Hbf to Wien Hbf
- Ave. Duration
- 1h 19m
- Frequency
- Once a week
- Estimated price
- Kč 800–2,400
- Website
- https://int.bahn.de/en
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Frankfurt to München Hbf
- Ave. Duration
- 3h 19m
- Frequency
- Twice daily
- Estimated price
- Kč 1,000–2,400
- Website
- https://www.ns.nl/en
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 46m
- Frequency
- Once daily
- Estimated price
- Kč 180–410
- Website
- https://www.ns.nl/en
Train from Mannheim, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 37 min
- Frequency
- Twice daily
- Estimated price
- Kč 280–650
- Website
- https://www.ns.nl/en
Train from Frankfurt to Siegburg Bf
- Ave. Duration
- 39 min
- Frequency
- Every 4 hours
- Estimated price
- Kč 380–850
- Website
- https://www.ns.nl/en
- Phone
- +49 221 800 20 80
- info@msm-gruppe.de
- Website
- msm-gruppe.de
Train from Frankfurt to München Hbf
- Ave. Duration
- 4h 12m
- Frequency
- Once a week
- Schedules at
- msm-gruppe.de
- Phone
- +49 30 200 73-0
- kommunikation@transdev.de
- Website
- transdev.de
Train from München Hbf to Salzburg Hauptbahnhof
- Ave. Duration
- 2h 2m
- Frequency
- Hourly
- Estimated price
- Kč 650–950
- Schedules at
- transdev.de
- Phone
- +43 1 89900
- service@westbahn.at
- Website
- westbahn.at
Train from München Hbf to Salzburg Hauptbahnhof
- Ave. Duration
- 1h 51m
- Frequency
- Every 4 hours
- Estimated price
- Kč 700–1,200
- Website
- https://westbahn.at/en/
- Phone
- +49 8024 997171
- info@brb.de
- Website
- brb.de
Train from München Hbf to Salzburg Hauptbahnhof
- Ave. Duration
- 1h 51m
- Frequency
- 5 times a day
- Estimated price
- Kč 1,300–2,900
- Schedules at
- brb.de
- Phone
- +43 (0) 5 1717
- Website
- oebb.at
Train from München Hbf to Salzburg Hauptbahnhof
- Ave. Duration
- 1h 51m
- Frequency
- Once daily
- Estimated price
- Kč 430–900
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket?cref=oebb-header
Train from Salzburg Hbf to Wien Hbf
- Ave. Duration
- 2h 52m
- Frequency
- Hourly
- Estimated price
- Kč 900–1,900
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket?cref=oebb-header
Train from Linz Hbf to Wien Hbf
- Ave. Duration
- 1h 31m
- Frequency
- Hourly
- Estimated price
- Kč 500–1,200
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket?cref=oebb-header
- Phone
- +48 22 322 22 22
- sekretariat@intercity.pl
- Website
- intercity.pl
Train from München Hbf to Salzburg Hauptbahnhof
- Ave. Duration
- 1h 59m
- Frequency
- Once daily
- Estimated price
- Kč 550–1,500
- Website
- https://www.intercity.pl/en/
Train from Salzburg Hbf to Wien Hbf
- Ave. Duration
- 2h 43m
- Frequency
- Once daily
- Estimated price
- Kč 1,100–3,100
- Website
- https://www.intercity.pl/en/
Train from Wroclaw Glowny to Usti Nad Orlici
- Ave. Duration
- 2h 19m
- Frequency
- 4 times a day
- Estimated price
- Kč 600–1,700
- Website
- https://www.intercity.pl/en/
Train from Linz Hbf to Wien Hbf
- Ave. Duration
- 1h 27m
- Frequency
- Once daily
- Estimated price
- Kč 650–1,800
- Website
- https://www.intercity.pl/en/
- Phone
- +420 221 111 122
- info@cd.cz
- Website
- cd.cz
Train from München Hbf to Salzburg Hauptbahnhof
- Ave. Duration
- 1h 59m
- Frequency
- Once daily
- Estimated price
- Kč 410–650
- Website
- https://www.cd.cz/en/default.htm
Train from Salzburg Hbf to Wien Hbf
- Ave. Duration
- 2h 43m
- Frequency
- Once daily
- Estimated price
- Kč 850–1,400
- Website
- https://www.cd.cz/en/default.htm
Train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazi
- Ave. Duration
- 2h 36m
- Frequency
- Hourly
- Estimated price
- Kč 700–1,100
- Website
- https://www.cd.cz/en/default.htm
Train from Usti Nad Orlici to Brno Hlavni Nadrazi
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- Kč 270–430
- Website
- https://www.cd.cz/en/default.htm
Train from Linz Hbf to Wien Hbf
- Ave. Duration
- 1h 27m
- Frequency
- Once daily
- Estimated price
- Kč 500–800
- Website
- https://www.cd.cz/en/default.htm
- Phone
- +43 (0)5 1717
- Website
- oebb.at
Train from Salzburg Hbf to Wien Hbf
- Ave. Duration
- 2h 25m
- Frequency
- Hourly
- Estimated price
- Kč 1,100–1,700
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/railjet
- Website
- https://shop.oebbtickets.at/en/ticket
- *
- Kč 1,100–1,700
Train from Wien Hbf to Brno Hlavni Nadrazi
- Ave. Duration
- 1h 31m
- Frequency
- Every 4 hours
- Estimated price
- Kč 600–950
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/railjet
- Website
- https://shop.oebbtickets.at/en/ticket
- *
- Kč 600–950
Train from Linz Hbf to Wien Hbf
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- Kč 700–1,100
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/railjet
- Website
- https://shop.oebbtickets.at/en/ticket
- *
- Kč 700–1,100
- Phone
- +43 (0) 5 1717
- Website
- oebb.at
Train from Salzburg Hbf to Wien Hbf
- Ave. Duration
- 2h 41m
- Frequency
- Once daily
- Estimated price
- Kč 1,700–2,900
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
Train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazi
- Ave. Duration
- 2h 37m
- Frequency
- 3 times a day
- Estimated price
- Kč 1,400–2,400
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
Train from Linz Hbf to Wien Hbf
- Ave. Duration
- 1h 29m
- Frequency
- Once daily
- Estimated price
- Kč 1,000–1,800
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- _AUSTRIAN_RAILWAYS_(ÖBB)
- Website
- oebb.at
Train from Salzburg Hbf to Wien Hbf
- Ave. Duration
- 2h 45m
- Frequency
- Twice a week
- Estimated price
- Kč 1,500–2,800
- Website
- https://www.oebb.at/en/
Night train from Frankfurt(Main)Sued to Praha Hlavni Nadrazi
- Ave. Duration
- 8h 57m
- Frequency
- Once daily
- Estimated price
- Kč 3,300–6,000
- Website
- https://www.oebb.at/en/
Train from Linz Hbf to Wien Hbf
- Ave. Duration
- 1h 26m
- Frequency
- Twice a week
- Estimated price
- Kč 900–1,700
- Website
- https://www.oebb.at/en/
- Phone
- +420 222 222 221
- info@regiojet.com
- Website
- regiojet.com
Train from Wien Hbf to Brno Hlavni Nadrazi
- Ave. Duration
- 1h 33m
- Frequency
- 4 times a day
- Estimated price
- Kč 210–330
- Website
- https://regiojet.com/
Train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazi
- Ave. Duration
- 2h 39m
- Frequency
- Every 3 hours
- Estimated price
- Kč 360–550
- Website
- https://regiojet.com/
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 21m
- Frequency
- Hourly
- Estimated price
- Kč 340–550
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 54 min
- Frequency
- Every 4 hours
- Estimated price
- Kč 350–490
- Schedules at
- suewex.de
- Phone
- +32 70 79 79 79
- Website
- belgiantrain.be
Train from Frankfurt to Siegburg Bf
- Ave. Duration
- 49 min
- Frequency
- Once a week
- Estimated price
- Kč 600–1,300
- Website
- https://www.belgiantrain.be/en
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Mainz central train station to Prague
- Ave. Duration
- 8h 25m
- Frequency
- Once daily
- Estimated price
- Kč 950–1,600
- Website
- https://www.flixbus.co.uk
Bus from Praha, Hlavní Nádraží to Brno
- Ave. Duration
- 2h 35m
- Frequency
- Every 3 hours
- Estimated price
- Kč 360–600
- Website
- https://www.flixbus.co.uk
- Phone
- +420 222 222 221
- info@regiojet.com
- Website
- regiojet.com
Bus from Praha, Hlavní Nádraží to Brno
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- Kč 360–550
- Website
- https://regiojet.com/
- Phone
- +38 098-888-11-08
- igoruzhanskyi@grandbus.com.ua
- Website
- grandbus.com.ua
Bus from Frankfurt, Hauptbahnhof FOB to Brno Hlavní Nádraží
- Ave. Duration
- 19h 21m
- Frequency
- Once daily
- Website
- https://www.grandbus.com.ua/en
Want to know more about travelling around Czechia
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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More Questions & Answers
Mainz to Brno bus services, operated by FlixBus, arrive at Prague station.
Mainz to Brno train services, operated by Deutsche Bahn Intercity (DB IC), arrive at München Hbf station.
Yes, the driving distance between Mainz to Brno is 744 km. It takes approximately 6h 17m to drive from Mainz to Brno.
Book your Mainz to Brno train tickets online with Omio.
Book your Mainz to Brno bus tickets online with Omio and FlixBus.
There are 765+ hotels available in Brno.





































































