There are 8 ways to get from Mainz to Brno by plane, train, bus, night train, car, or car train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Václav Havel Airport Prague, train
best- Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)plane FRA - PRG
- Take the train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazitrain
5h 44mKč 2,075–6,738Bus via Prague
cheapest- Take the bus from Mainz central train station to Praguebus N1310
- Take the bus from Praha, Hlavní Nádraží to Brnobus 260 / ...
12hKč 1,299–2,222Train
- Take the train from Frankfurt(M) Flughafen Fernbf to Muenchen Hbftrain Ice
- Take the train from Muenchen Hbf Gl.5-10 to Linz Hbftrain 961 / ...
- Take the train from Linz Hbf to Wien Hbftrain Rjx / ...
- Take the train from Wien Hbf to Brno Hlavni Nadrazitrain Rj / ...
12h 20mKč 2,467–8,108Night train, train
- Take the night train from Frankfurt(Main)Sued to Praha Hlavni Nadrazinighttrain En
- Take the train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazitrain Rj / ...
14h 8mKč 4,271–9,301Fly to Vienna International Airport, train
- Fly from Frankfurt (FRA) to Vienna International Airport (VIE)plane FRA - VIE
- Take the train from Wien Hbf to Brno Hlavni Nadrazitrain
6h 34mKč 1,917–5,258Bus
- Take the bus from Frankfurt, Hauptbahnhof FOB to Brno Hlavní Nádražíbus Ivano-Frankivsk
20h 51mDrive 743.5 km
- Drive from Mainz to Brnocar 743.5 km
6h 17mKč 2,748–3,969Drive, car train
- Drive from Mainz to Fuldacar
- Take the car train from Fulda to Salzburg Hbfcartrain
- Drive from Salzburg Hbf to Brnocar
8h 43mKč 4,185–5,701
Mainz to Brno by bus
Questions & Answers
The cheapest way to get from Mainz to Brno is to bus via Prague which costs 1 300 Kč - 2 300 Kč and takes 12h.
The fastest way to get from Mainz to Brno is to fly and train which takes 5h 44m and costs 2 000 Kč - 7 000 Kč.
No, there is no direct bus from Mainz station to Brno. However, there are services departing from Mainz central train station and arriving at Brno via Praha, Hlavní Nádraží. The journey, including transfers, takes approximately 12h.
No, there is no direct train from Mainz to Brno. However, there are services departing from Mainz Hbf and arriving at Brno Hlavni Nadrazi via Frankfurt(M) Flughafen Fernbf, Muenchen Hbf Gl.5-10, Linz Hbf and Wien Hbf. The journey, including transfers, takes approximately 12h 20m.
The distance between Mainz and Brno is 701 km. The road distance is 743.5 km.
The best way to get from Mainz to Brno without a car is to bus via Prague which takes 12h and costs 1 300 Kč - 2 300 Kč.
It takes approximately 5h 44m to get from Mainz to Brno, including transfers.
Mainz to Brno bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Brno train services, operated by Nederlandse Spoorwegen (NS), depart from Frankfurt(M) Flughafen Fernbf station.
The best way to get from Mainz to Brno is to bus via Prague which takes 12h and costs 1 300 Kč - 2 300 Kč. Alternatively, you can train, which costs 2 400 Kč - 8 500 Kč and takes 12h 20m.
What companies run services between Mainz, Germany and Brno, Czechia?
You can take a bus from Mainz central train station to Brno via Prague and Praha, Hlavní Nádraží in around 12h. Alternatively, you can take a train from Mainz Hbf to Brno Hlavni Nadrazi via Frankfurt(M) Flughafen Fernbf, Muenchen Hbf Gl.5-10, Linz Hbf, and Wien Hbf in around 12h 20m.
- Website
- lufthansa.com
Flights from Frankfurt to Václav Havel Airport Prague
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- Kč 1,500–10,000
Flights from Frankfurt to Vienna International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- Kč 1,800–4,900
- Website
- austrian.com
Flights from Frankfurt to Vienna International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- Kč 1,800–4,900
- Website
- condor.com
Flights from Frankfurt to Václav Havel Airport Prague
- Ave. Duration
- 58 min
- When
- Every day
- Estimated price
- Kč 1,600–3,900
Flights from Frankfurt to Vienna International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- Kč 1,600–3,900
- Website
- airdolomiti.it
Flights from Frankfurt to Václav Havel Airport Prague
- Ave. Duration
- 1h 5m
- When
- Tuesday to Sunday
- Estimated price
- Kč 2,200–8,500
- Phone
- +420 221 111 122
- info@cd.cz
- Website
- cd.cz
Train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazi
- Ave. Duration
- 2h 36m
- Frequency
- Hourly
- Estimated price
- Kč 650–1,200
- Website
- https://www.cd.cz/en/default.htm
Train from Muenchen Hbf Gl.5-10 to Linz Hbf
- Ave. Duration
- 3h 8m
- Frequency
- Once daily
- Estimated price
- Kč 700–1,300
- Website
- https://www.cd.cz/en/default.htm
Train from Linz Hbf to Wien Hbf
- Ave. Duration
- 1h 31m
- Frequency
- Once daily
- Estimated price
- Kč 500–900
- Website
- https://www.cd.cz/en/default.htm
- Phone
- +420 222 222 221
- info@regiojet.cz
- Website
- regiojet.com
Train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazi
- Ave. Duration
- 2h 39m
- Frequency
- Every 3 hours
- Estimated price
- Kč 350–600
- Website
- https://regiojet.com/
Train from Wien Hbf to Brno Hlavni Nadrazi
- Ave. Duration
- 1h 33m
- Frequency
- 4 times a day
- Estimated price
- Kč 200–330
- Website
- https://regiojet.com/
- Phone
- +43 5 1717
- Website
- oebb.at
Train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazi
- Ave. Duration
- 2h 37m
- Frequency
- 3 times a day
- Estimated price
- Kč 1,300–2,300
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
Train from Linz Hbf to Wien Hbf
- Ave. Duration
- 1h 22m
- Frequency
- Once daily
- Estimated price
- Kč 950–1,700
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Frankfurt(M) Flughafen Fernbf to Muenchen Hbf
- Ave. Duration
- 3h 19m
- Frequency
- 3 times a day
- Estimated price
- Kč 1,000–2,600
- Website
- https://www.ns.nl/en
- Phone
- +43 1 89900
- meinenachricht@westbahn.at
- Website
- westbahn.at
Train from Muenchen Hbf Gl.5-10 to Linz Hbf
- Ave. Duration
- 2h 46m
- Frequency
- Every 4 hours
- Estimated price
- Kč 1,200–2,100
- Website
- https://westbahn.at/en/
- Phone
- +48 22 322 22 22
- infokraj@intercity.pl
- Website
- intercity.pl
Train from Muenchen Hbf Gl.5-10 to Linz Hbf
- Ave. Duration
- 3h 8m
- Frequency
- Twice daily
- Estimated price
- Kč 1,000–2,400
- Website
- https://www.intercity.pl/en/
Train from Linz Hbf to Wien Hbf
- Ave. Duration
- 1h 31m
- Frequency
- Twice daily
- Estimated price
- Kč 700–1,600
- Website
- https://www.intercity.pl/en/
- Phone
- +43 5 1717
- Website
- oebb.at
Train from Muenchen Hbf Gl.5-10 to Linz Hbf
- Ave. Duration
- 3h 9m
- Frequency
- Once daily
- Estimated price
- Kč 750–1,700
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket?cref=oebb-header
Train from Linz Hbf to Wien Hbf
- Ave. Duration
- 1h 31m
- Frequency
- Hourly
- Estimated price
- Kč 500–1,200
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket?cref=oebb-header
Train from Linz Hbf to Wien Hbf
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- Kč 700–1,100
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/railjet
- *
- Kč 700–1,100
Train from Wien Hbf to Brno Hlavni Nadrazi
- Ave. Duration
- 1h 31m
- Frequency
- Every 3 hours
- Estimated price
- Kč 600–950
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/railjet
- *
- Kč 600–950
Train from Linz Hbf to Wien Hbf
- Ave. Duration
- 1h 27m
- Frequency
- Twice a week
- Estimated price
- Kč 950–1,700
- Website
- https://www.oebb.at/en/
Night train from Frankfurt(Main)Sued to Praha Hlavni Nadrazi
- Ave. Duration
- 8h 57m
- Frequency
- Once daily
- Estimated price
- Kč 3,500–6,500
- Website
- https://www.oebb.at/en/
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Linz Hbf to Wien Hbf
- Ave. Duration
- 1h 19m
- Frequency
- Once a week
- Estimated price
- Kč 850–2,000
- Website
- https://int.bahn.de/en
- Phone
- +49 (0) 221 800 20 820
- info@urlaubs-express.de
- Website
- urlaubs-express.de
Car train from Fulda to Salzburg Hbf
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- Kč 2,300–2,800
- Website
- https://urlaubs-express.de/?lang=en
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Mainz central train station to Prague
- Ave. Duration
- 8h 25m
- Frequency
- Once daily
- Estimated price
- Kč 950–1,700
- Website
- https://www.flixbus.co.uk
Bus from Praha, Hlavní Nádraží to Brno
- Ave. Duration
- 2h 35m
- Frequency
- Every 3 hours
- Estimated price
- Kč 350–600
- Website
- https://www.flixbus.co.uk
- Phone
- +38 098-888-11-08
- igoruzhanskyi@grandbus.com.ua
- Website
- grandbus.com.ua
Bus from Frankfurt, Hauptbahnhof FOB to Brno Hlavní Nádraží
- Ave. Duration
- 19h 21m
- Frequency
- Once daily
- Website
- https://www.grandbus.com.ua/en
Want to know more about travelling around Czechia
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
More Questions & Answers
Mainz to Brno bus services, operated by FlixBus, arrive at Prague station.
Mainz to Brno train services, operated by Nederlandse Spoorwegen (NS), arrive at Muenchen Hbf station.
Yes, the driving distance between Mainz to Brno is 744 km. It takes approximately 6h 17m to drive from Mainz to Brno.
Book your Mainz to Brno train tickets online with Omio.
Book your Mainz to Brno bus tickets online with Omio and FlixBus.
There are 67+ hotels available in Brno.






















































