Rome2Rio

How to get fromMaine to Iowaby plane, bus, train, bus (Amtrak, Flixbus, Greyhound), or car

Find Transport to Iowa

See all options

There are 9 ways to get from Maine to Iowa by plane, bus, train, bus (Amtrak, Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Portland to Des Moines

    best
    1. Fly from Portland (PWM) to Des Moines (DSM)plane plane PWM - DSM
    5h 6m
    $147–635

  2. Fly Bangor to Quad City International Airport

    cheapest
    1. Fly from Bangor (BGR) to Quad City International Airport (MLI)plane plane BGR - MLI
    9h 37m
    $98–484

  3. Bus, train

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the train from Boston to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    33h 38m
    $351–894

  4. Bus

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the bus from New York Midtown to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to Des Moinesbus bus
    36h 49m
    $261–424

  5. Drive  1,352 mi

    1. Drive from Portland to Des Moinescar car 1,352 mi
    24h 29m
    $247–357

  6. Fly Portland to Omaha

    1. Fly from Portland (PWM) to Omaha (OMA)plane plane PWM - OMA
    5h 15m
    $199–840

  7. Fly Portland to The Eastern Iowa Airport

    1. Fly from Portland (PWM) to The Eastern Iowa Airport (CID)plane plane PWM - CID
    5h 34m
    $161–637

  8. Fly Portland to Quad City International Airport

    1. Fly from Portland (PWM) to Quad City International Airport (MLI)plane plane PWM - MLI
    6h 43m
    $119–575

  9. Bus, train via Galesburg

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the train from Boston to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    35h 30m
    $371–984

Portland (PWM) to Des Moines (DSM) flights

Calendar89Weekly Planes
Duration6h 12mAverage Duration
Ticket$128Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Maine to Iowa.ExpandLaunch map view
  • Distance: 1,198.6 mi
  • Duration: 5h 6m

What companies run services between Maine, USA and Iowa, USA?

Southwest Airlines, Delta, and two other airlines fly from Portland (PWM) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Portland Public Library to Des Moines via Portland, ME, Boston, MA - South Station, Boston, New York Midtown, Chicago Bus Station, and Des Moines in around 36h 49m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There