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How to get fromMaine to Iowaby plane, bus, train, bus (Amtrak, Flixbus) or car

Find Transport to Iowa

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There are 9 ways to get from Maine to Iowa by plane, bus, train, bus (Amtrak, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Portland to Des Moines

    best
    1. Fly from Portland (PWM) to Des Moines (DSM)plane plane PWM - DSM
    5h 41m
    $255–1,128
  2. Fly Bangor to Quad City International Airport

    cheapest
    1. Fly from Bangor (BGR) to Quad City International Airport (MLI)plane plane BGR - MLI
    8h 15m
    $104–504
  3. Bus, train via Des Moines

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the train from Boston to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    33h 43m
    $216–855
  4. Bus

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the bus from New York Midtown to Chicago Bus Stationbus bus
    4. Take the bus from Chicago to Des Moinesbus bus
    37h 24m
    $198–489
  5. Drive 1,352.8 mi

    1. Drive from Portland to Des Moinescar car 1,352.8 mi
    24h 15m
    $247–357
  6. Fly Portland to Waterloo Municipal Airport

    1. Fly from Portland (PWM) to Waterloo Municipal Airport (ALO)plane plane PWM - ALO
    5h 50m
    $135–577
  7. Fly Portland to Quad City International Airport

    1. Fly from Portland (PWM) to Quad City International Airport (MLI)plane plane PWM - MLI
    7h 14m
    $113–537
  8. Fly Portland to The Eastern Iowa Airport

    1. Fly from Portland (PWM) to The Eastern Iowa Airport (CID)plane plane PWM - CID
    7h 10m
    $136–588
  9. Bus, train

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the train from Boston to Chicago Union Stationtrain train
    3. Take the bus from Chicago to Des Moinesbus bus
    34h 13m
    $218–909

Maine to Iowa by bus

Calendar7Weekly Buses
Duration37h 24mAverage Duration
Ticket$198Cheapest Price
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Questions & Answers

What companies run services between Maine, USA and Iowa, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Portland (PWM) to Des Moines (DSM) every 4 hours. Alternatively, you can take a bus from Portland Public Library to Des Moines via Portland, ME, Boston, MA - South Station, Boston, New York Midtown, and Chicago in around 37h 24m.

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