Rome2Rio

How to get fromMaine to IowaBy plane, bus (Amtrak, Flixbus, Greyhound), bus, train, or car

Find Transport to Iowa

See all options

There are 8 ways to get from Maine to Iowa by plane, bus (Amtrak, Flixbus, Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Portland to Des Moines

    best
    1. Fly from Portland (PWM) to Des Moines (DSM)plane plane PWM - DSM
    5h 9m
    $316–1,416
  2. Fly Bangor to Quad City International Airport

    cheapest
    1. Fly from Bangor (BGR) to Quad City International Airport (MLI)plane plane BGR - MLI
    7h 46m
    $114–604
  3. Bus

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the bus from New York Midtown to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to Des Moinesbus bus
    33h 13m
    $218–420
  4. Bus, train

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the train from Boston to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    33h 39m
    $361–820
  5. Drive 1,352.1 mi

    1. Drive from Portland to Des Moinescar car 1,352.1 mi
    24h 30m
    $247–357
  6. Fly Portland to Waterloo Municipal Airport

    1. Fly from Portland (PWM) to Waterloo Municipal Airport (ALO)plane plane PWM - ALO
    6h 37m
    $162–707
  7. Fly Portland to Quad City International Airport

    1. Fly from Portland (PWM) to Quad City International Airport (MLI)plane plane PWM - MLI
    6h 35m
    $137–658
  8. Train, bus

    1. Take the train from Portland to Bostontrain train
    2. Take the train from Boston to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Bloomington-Normaltrain train
    4. Take the bus from Bloomington-Normal to Des Moinesbus bus
    37h 54m
    $388–903

Portland (PWM) to Des Moines (DSM) flights

Calendar76Weekly Planes
Duration6h 15mAverage Duration
Ticket$298Cheapest Price
See schedules

Questions & Answers

What companies run services between Maine, USA and Iowa, USA?

Delta, Southwest Airlines, and two other airlines fly from Portland (PWM) to Des Moines (DSM) every 2 hours. Alternatively, you can take a bus from Portland Public Library to Des Moines via Portland, ME, Boston, MA - South Station, Boston, New York Midtown, Chicago Bus Station, and Des Moines in around 33h 13m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound