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How to get fromIllinois to Iowaby bus (Greyhound), car, plane or bus

Find Transport to Iowa

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There are 3 ways to get from Illinois to Iowa by bus (Greyhound), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123 / ...
    6h 39m
    $54–106
  2. Fly, line 10 bus

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Quad City International Airport (MLI)plane plane ORD - MLI
    2. Take the bus from Centre Station to Districtbus bus
    4h 21m
    $40–257
  3. Drive 330 mi

    1. Drive from Chicago to Des Moinescar car 330 mi
    5h 32m
    $61–87

Chicago O'Hare International Airport (ORD) to Quad City International Airport (MLI) flights

Calendar41Weekly Planes
Duration1h 12mAverage Duration
Ticket$35Cheapest Price
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Questions & Answers

What companies run services between Illinois, USA and Iowa, USA?

Greyhound USA operates a bus from Chicago Bus Station to Des Moines 3 times a day. Tickets cost $45–95 and the journey takes 6h 34m.

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