There are 9 ways to get from Lugano to Mainz by train (Trenitalia), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Lugano to Mannheim Hbftrain Ec
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
7h 7m€122–181Bus
cheapest- Take the bus from Lugano to Frankfurt central train stationbus FlixBus N474
10h 45m€42–72Drive 587.3 km
- Drive from Lugano to Mainzcar 587.3 km
5h 25m€102–148Train to Zurich Airport, fly
- Take the train from Lugano to Zürich HBtrain
- Fly from Zurich Airport (ZRH) to Frankfurt (FRA)plane ZRH - FRA
4h 39m€149–324Train via Basel
- Take the train from Lugano to Basel SBBtrain Ec
- Take the train from Basel SBB to Mannheim, Hauptbahnhoftrain 20 / ...
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
7h 11m€78–233Bus, train
- Take the bus from Lugano to Zürichbus
- Take the bus from Zürich to Mannheim - Bus Stationbus
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
11h 19m€65–95Train to Milano Malpensa Airport, fly
- Take the train from Lugano to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Frankfurt (FRA)plane MXP - FRA
5h 22m€73–200Train to Milan Linate Airport, fly
- Take the train from Lugano to Seregnotrain
- Fly from Milan Linate Airport (LIN) to Frankfurt (FRA)plane LIN - FRA
5h 55m€51–165Train to Basel, fly
- Take the train from Lugano to Basel SBBtrain
- Fly from Basel (BSL) to Frankfurt (FRA)plane BSL - FRA
6h 52m€140–401
Lugano to Mainz by train
Questions & Answers
The cheapest way to get from Lugano to Mainz is to bus which costs €40 - €75 and takes 10h 45m.
The fastest way to get from Lugano to Mainz is to train and fly which takes 4h 39m and costs €140 - €330.
No, there is no direct bus from Lugano to Mainz station. However, there are services departing from Lugano and arriving at Mainz central train station via Frankfurt central train station. The journey, including transfers, takes approximately 10h 45m.
No, there is no direct train from Lugano to Mainz. However, there are services departing from Lugano and arriving at Mainz, Römisches Theater via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 7h 7m.
The distance between Lugano and Mainz is 586 km. The road distance is 587.3 km.
The best way to get from Lugano to Mainz without a car is to train which takes 7h 7m and costs €120 - €190.
It takes approximately 7h 7m to get from Lugano to Mainz, including transfers.
Lugano to Mainz bus services, operated by FlixBus, depart from Lugano station.
Lugano to Mainz train services, operated by Trenitalia EuroCity, depart from Lugano station.
The best way to get from Lugano to Mainz is to train which takes 7h 7m and costs €120 - €190. Alternatively, you can bus, which costs €40 - €75 and takes 10h 45m.
What companies run services between Lugano, Switzerland and Mainz, Germany?
You can take a train from Lugano to Mainz, Römisches Theater via Mannheim Hbf and Mannheim, Hauptbahnhof in around 7h 7m. Alternatively, FlixBus operates a bus from Lugano to Frankfurt central train station once daily. Tickets cost €40–70 and the journey takes 9h 5m.
- Website
- lufthansa.com
Flights from Zurich Airport to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €60–260
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €60–270
Flights from Milano Malpensa Airport to Frankfurt via Munich
- Ave. Duration
- 3h 10m
- When
- Monday and Tuesday
- Estimated price
- €75–300
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €65–320
Flights from Milan Linate Airport to Frankfurt via Munich
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €65–350
Flights from Basel to Frankfurt
- Ave. Duration
- 1h 4m
- When
- Every day
- Estimated price
- €70–310
Flights from Basel to Frankfurt via Munich
- Ave. Duration
- 2h 50m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €75–320
- Website
- airdolomiti.it
Flights from Zurich Airport to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €75–260
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €70–270
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €65–320
Flights from Basel to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €85–310
- Website
- swiss.com
Flights from Zurich Airport to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €60–260
Flights from Milano Malpensa Airport to Frankfurt via Zurich Airport
- Ave. Duration
- 3h 12m
- When
- Every day
- Estimated price
- €60–270
Flights from Basel to Frankfurt
- Ave. Duration
- 1h
- When
- Monday and Sunday
- Estimated price
- €70–300
- Website
- condor.com
Flights from Zurich Airport to Frankfurt
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- €75–160
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- €50–140
- Website
- easyjet.com
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–130
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Lugano to Mannheim Hbf
- Ave. Duration
- 5h 28m
- Frequency
- Once daily
- Estimated price
- €100–170
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €110–170
- 2nd Class
- €100–150
Train from Lugano to Basel SBB
- Ave. Duration
- 2h 53m
- Frequency
- Twice daily
- Estimated price
- €55–110
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €75–110
- 2nd Class
- €55–80
Train from Basel SBB to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 12m
- Frequency
- Once daily
- Estimated price
- €55–110
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €75–110
- 2nd Class
- €55–80
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €13–19
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 57 min
- Frequency
- 5 times a week
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Lugano to Zürich HB
- Ave. Duration
- 1h 53m
- Frequency
- Hourly
- Estimated price
- €60–120
- Website
- https://www.sbb.ch/en
Train from Lugano to Basel SBB
- Ave. Duration
- 2h 53m
- Frequency
- Every 3 hours
- Estimated price
- €85–160
- Website
- https://www.sbb.ch/en
Train from Lugano to Seregno
- Ave. Duration
- 56 min
- Frequency
- Hourly
- Estimated price
- €25–50
- Website
- https://www.sbb.ch/en
- Phone
- +49 (0) 7531 915109
- info@sbb-deutschland.de
- Website
- sbb-deutschland.de
Train from Lugano to Basel SBB
- Ave. Duration
- 2h 56m
- Frequency
- Once daily
- Estimated price
- €20–25
- Schedules at
- sbb-deutschland.de
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Basel SBB to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 14m
- Frequency
- Hourly
- Estimated price
- €49–54
- Website
- https://int.bahn.de/en
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Lugano to Malpensa Aeroporto T1
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- €6–8
- Website
- https://www.trenord.it/en/
Train from Lugano to Seregno
- Ave. Duration
- 56 min
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- https://www.trenord.it/en/
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Lugano to Frankfurt central train station
- Ave. Duration
- 9h 5m
- Frequency
- Once daily
- Estimated price
- €40–70
- Website
- https://www.flixbus.co.uk
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Lugano to Zürich
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- €22–30
- Website
- https://www.blablacar.co.uk/bus
Bus from Zürich to Mannheim - Bus Station
- Ave. Duration
- 6h 10m
- Frequency
- 3 times a week
- Estimated price
- €30–45
- Website
- https://www.blablacar.co.uk/bus
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More Questions & Answers
Lugano to Mainz bus services, operated by FlixBus, arrive at Frankfurt central train station.
Lugano to Mainz train services, operated by Trenitalia EuroCity, arrive at Mannheim Hbf station.
Yes, the driving distance between Lugano to Mainz is 587 km. It takes approximately 5h 25m to drive from Lugano to Mainz.
Book your Lugano to Mainz train tickets online with Omio.
Book your Lugano to Mainz bus tickets online with FlixBus.
There are 1155+ hotels available in Mainz.









































