There are 8 ways to get from Lugano to Mainz by train (Trenitalia), bus, car, train, plane, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Lugano to Mannheim Hbftrain Ec
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
7h 7m€123–182Bus
cheapest- Take the bus from Lugano to Frankfurt central train stationbus FlixBus N474
10h 45m€46–79Drive 587.3 km
- Drive from Lugano to Mainzcar 587.3 km
5h 24m€102–147Train to Milano Malpensa Airport, fly
- Take the train from Lugano to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Frankfurt (FRA)plane MXP - FRA
5h 22m€81–210Train via Basel
- Take the train from Lugano to Basel SBBtrain Ic21 / ...
- Take the train from Basel SBB to Frankfurttrain 20 / ...
7h 16m€88–611Bus, night train, train
- Take the bus from Lugano Via Giacomo and Filippo Ciani to Zurich Central Bus Station Sihlquaibus
- Take the night train from Zuerich Hb to Mannheim Hbfnighttrain Nj
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
10h 29mTrain to Milan Linate Airport, fly
- Take the train from Lugano to Seregnotrain
- Fly from Milan Linate Airport (LIN) to Frankfurt (FRA)plane LIN - FRA
6h€54–265Train to Zurich Airport, fly
- Take the train from Lugano to Zürich HBtrain
- Fly from Zurich Airport (ZRH) to Frankfurt (FRA)plane ZRH - FRA
5h 44m€147–414
Lugano to Mainz by train
Questions & Answers
The cheapest way to get from Lugano to Mainz is to bus which costs €45 - €80 and takes 10h 45m.
The fastest way to get from Lugano to Mainz is to train and fly which takes 5h 22m and costs €80 - €210.
No, there is no direct bus from Lugano to Mainz station. However, there are services departing from Lugano and arriving at Mainz central train station via Frankfurt central train station. The journey, including transfers, takes approximately 10h 45m.
No, there is no direct train from Lugano to Mainz. However, there are services departing from Lugano and arriving at Mainz, Römisches Theater via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 7h 7m.
The distance between Lugano and Mainz is 586 km. The road distance is 587.3 km.
The best way to get from Lugano to Mainz without a car is to train which takes 7h 7m and costs €120 - €190.
It takes approximately 7h 7m to get from Lugano to Mainz, including transfers.
Lugano to Mainz bus services, operated by FlixBus, depart from Lugano station.
Lugano to Mainz train services, operated by Trenitalia EuroCity, depart from Lugano station.
The best way to get from Lugano to Mainz is to train which takes 7h 7m and costs €120 - €190. Alternatively, you can bus, which costs €45 - €80 and takes 10h 45m.
What companies run services between Lugano, Switzerland and Mainz, Germany?
You can take a train from Lugano to Mainz, Römisches Theater via Mannheim Hbf and Mannheim, Hauptbahnhof in around 7h 7m. Alternatively, FlixBus operates a bus from Lugano to Frankfurt central train station once daily. Tickets cost €40–75 and the journey takes 9h 5m.
- Website
- lufthansa.com
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €75–210
Flights from Milano Malpensa Airport to Frankfurt via Munich
- Ave. Duration
- 3h 10m
- When
- Monday to Friday
- Estimated price
- €75–210
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €110–420
Flights from Milan Linate Airport to Frankfurt via Munich
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €110–460
Flights from Zurich Airport to Frankfurt
- Ave. Duration
- 1h 4m
- When
- Every day
- Estimated price
- €85–410
Flights from Zurich Airport to Frankfurt via Stuttgart
- Ave. Duration
- 2h 30m
- When
- Tuesday to Sunday
- Estimated price
- €90–390
Flights from Zurich Airport to Frankfurt via Munich
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- €95–400
- Website
- swiss.com
Flights from Milano Malpensa Airport to Frankfurt via Zurich Airport
- Ave. Duration
- 3h 20m
- When
- Monday to Saturday
- Estimated price
- €70–290
Flights from Zurich Airport to Frankfurt
- Ave. Duration
- 1h 4m
- When
- Every day
- Estimated price
- €85–410
- Website
- airdolomiti.it
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €85–180
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €110–420
Flights from Zurich Airport to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €110–410
- Website
- condor.com
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- €60–160
Flights from Zurich Airport to Frankfurt
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- €75–190
- Website
- easyjet.com
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €40–160
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Lugano to Mannheim Hbf
- Ave. Duration
- 5h 28m
- Frequency
- Once daily
- Estimated price
- €100–170
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €110–170
- 2nd Class
- €100–150
Train from Lugano to Basel SBB
- Ave. Duration
- 2h 57m
- Frequency
- Twice daily
- Estimated price
- €55–110
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €75–110
- 2nd Class
- €55–80
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €14–21
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 57 min
- Frequency
- 5 times a week
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Lugano to Malpensa Aeroporto T1
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- €6–8
- Website
- https://www.trenord.it/en/
Train from Lugano to Seregno
- Ave. Duration
- 56 min
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- https://www.trenord.it/en/
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Lugano to Basel SBB
- Ave. Duration
- 2h 53m
- Frequency
- Every 3 hours
- Estimated price
- €90–260
- Website
- https://www.sbb.ch/en
Train from Basel SBB to Frankfurt
- Ave. Duration
- 2h 53m
- Frequency
- 6 times a week
- Estimated price
- €110–340
- Website
- https://www.sbb.ch/en
Train from Lugano to Seregno
- Ave. Duration
- 56 min
- Frequency
- Hourly
- Estimated price
- €19–60
- Website
- https://www.sbb.ch/en
Train from Lugano to Zürich HB
- Ave. Duration
- 1h 53m
- Frequency
- Hourly
- Estimated price
- €60–180
- Website
- https://www.sbb.ch/en
- Phone
- +49 (0) 7531 915109
- info@sbb-deutschland.de
- Website
- sbb-deutschland.de
Train from Lugano to Basel SBB
- Ave. Duration
- 2h 56m
- Frequency
- Once daily
- Estimated price
- €20–25
- Schedules at
- sbb-deutschland.de
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Basel SBB to Frankfurt
- Ave. Duration
- 2h 54m
- Frequency
- Hourly
- Estimated price
- €60–150
- Website
- https://int.bahn.de/en
- Phone
- +43 51717
- Website
- nightjet.com
Night train from Zuerich Hb to Mannheim Hbf
- Ave. Duration
- 4h 21m
- Frequency
- Once a week
- Estimated price
- €27–95
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €93–95
- Couchette Carriage
- €55–70
- Seating Carriage
- €27–33
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Lugano to Frankfurt central train station
- Ave. Duration
- 9h 5m
- Frequency
- Once daily
- Estimated price
- €40–75
- Website
- https://www.flixbus.co.uk
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More Questions & Answers
Lugano to Mainz bus services, operated by FlixBus, arrive at Frankfurt central train station.
Lugano to Mainz train services, operated by Trenitalia EuroCity, arrive at Mannheim Hbf station.
Yes, the driving distance between Lugano to Mainz is 587 km. It takes approximately 5h 24m to drive from Lugano to Mainz.
Book your Lugano to Mainz train tickets online with Omio.
Book your Lugano to Mainz bus tickets online with FlixBus.
There are 412+ hotels available in Mainz.









































