There are 8 ways to get from Como to Mainz by train (Trenitalia), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Como S.Giovanni to Mannheim Hbftrain Ec
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
7h 47m€126–222Train to Milan Linate Airport, fly
cheapest- Take the train from Como S.Giovanni to Monzatrain
- Fly from Milan Linate Airport (LIN) to Frankfurt (FRA)plane LIN - FRA
5h 26m€45–178Bus
- Take the bus from Como to Mühlheim am Mainbus
8h 13m€84–129Drive 618.6 km
- Drive from Como to Mainzcar 618.6 km
5h 47m€100–144Train to Milano Malpensa Airport, fly
- Take the train from Como Lago to Saronnotrain
- Fly from Milano Malpensa Airport (MXP) to Frankfurt (FRA)plane MXP - FRA
4h 51m€65–198Train via Basel
- Take the train from Como S.Giovanni to Zuerich Hbtrain Ec
- Take the train from Zürich HB to Basel SBBtrain Ice / ...
- Take the train from Basel SBB to Mannheim, Hauptbahnhoftrain 12 / ...
- Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain S5 / ...
8h 28m€113–294Train, bus
- Take the train from Como S. Giovanni to Zürich HBtrain Ec
- Take the bus from Zurich Bus Station to Mainz central train stationbus FlixBus 476
11h 41m€97–149Train to Zurich Airport, fly
- Take the train from Como S.Giovanni to Zuerich Hbtrain
- Fly from Zurich Airport (ZRH) to Frankfurt (FRA)plane ZRH - FRA
6h 24m€151–333
Como to Mainz by train
Comparing Your Travel Options
The cheapest way to get from Como to Mainz is to train and fly which costs €40 - €180 and takes 5h 26m.
The fastest way to get from Como to Mainz is to train and fly which takes 4h 51m and costs €65 - €200.
No, there is no direct bus from Como to Mainz. However, there are services departing from Como and arriving at Frankfurt via Mühlheim and Obertshausen Bahnhof. The journey, including transfers, takes approximately 8h 13m.
No, there is no direct train from Como to Mainz. However, there are services departing from Como S.Giovanni and arriving at Mainz, Römisches Theater via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 7h 47m.
The distance between Como and Mainz is 616 km. The road distance is 618.6 km.
The best way to get from Como to Mainz without a car is to train which takes 7h 47m and costs €120 - €230.
It takes approximately 7h 47m to get from Como to Mainz, including transfers.
Como to Mainz bus services, operated by Onebus, depart from Como station.
Como to Mainz train services, operated by Trenitalia EuroCity, depart from Como S.Giovanni station.
The best way to get from Como to Mainz is to train which takes 7h 47m and costs €120 - €230. Alternatively, you can bus, which costs €80 - €130 and takes 8h 13m.
What companies run services between Como, Italy and Mainz, Germany?
You can take a train from Como S.Giovanni to Mainz, Römisches Theater via Mannheim Hbf and Mannheim, Hauptbahnhof in around 7h 47m. Alternatively, Onebus operates a bus from Como to Mühlheim am Main once a week. Tickets cost €80–110 and the journey takes 5h 32m.
- Website
- lufthansa.com
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €75–340
Flights from Milano Malpensa Airport to Frankfurt via Munich
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- €110–370
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €50–400
Flights from Milan Linate Airport to Frankfurt via Munich
- Ave. Duration
- 3h 21m
- When
- Every day
- Estimated price
- €50–340
Flights from Zurich Airport to Frankfurt
- Ave. Duration
- 1h 4m
- When
- Every day
- Estimated price
- €70–350
- Website
- swiss.com
Flights from Milano Malpensa Airport to Frankfurt via Zurich Airport
- Ave. Duration
- 3h 20m
- When
- Monday to Saturday
- Estimated price
- €65–240
Flights from Zurich Airport to Frankfurt
- Ave. Duration
- 1h 4m
- When
- Every day
- Estimated price
- €70–350
- Website
- airdolomiti.it
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €110–340
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €50–400
Flights from Zurich Airport to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €110–350
- Website
- condor.com
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- €55–160
Flights from Zurich Airport to Frankfurt
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- €95–210
- Website
- easyjet.com
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–140
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- Trenitalia Eurocity
Train from Como S.Giovanni to Mannheim Hbf
- Ave. Duration
- 6h 7m
- Frequency
- Twice daily
- Estimated price
- €110–170
- Website
- Trenitalia Eurocity
- 1st Class
- €120–170
- 2nd Class
- €110–150
Train from Como S.Giovanni to Zuerich Hb
- Ave. Duration
- 2h 36m
- Frequency
- Hourly
- Estimated price
- €45–95
- Website
- Trenitalia Eurocity
- 1st Class
- €65–95
- 2nd Class
- €45–65
Train from Basel SBB to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 12m
- Frequency
- Twice daily
- Estimated price
- €55–110
- Website
- Trenitalia Eurocity
- 1st Class
- €75–110
- 2nd Class
- €55–80
Train from Como S.Giovanni to Zuerich Hb
- Ave. Duration
- 2h 36m
- Frequency
- Hourly
- Estimated price
- €45–95
- Website
- Trenitalia Eurocity
- 1st Class
- €65–95
- 2nd Class
- €45–65
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €11–55
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 1h 23m
- Frequency
- Hourly
- Estimated price
- €11–55
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 57 min
- Frequency
- 6 times a week
- Estimated price
- €14–20
- Schedules at
- Süwex
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 52 min
- Frequency
- Every 4 hours
- Estimated price
- €14–20
- Schedules at
- Süwex
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- Trenord
Train from Como Lago to Saronno
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- €3–4
- Website
- Trenord
Train from Como S.Giovanni to Monza
- Ave. Duration
- 41 min
- Frequency
- Every 30 minutes
- Estimated price
- €3–5
- Website
- Trenord
- Phone
- +49 (0) 7531 915109
- info@sbb-deutschland.de
- Website
- SBB GmbH
Train from Zürich HB to Basel SBB
- Ave. Duration
- 53 min
- Frequency
- Every 2 hours
- Estimated price
- €8–11
- Schedules at
- SBB GmbH
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Zürich HB to Basel SBB
- Ave. Duration
- 53 min
- Frequency
- 3 times a day
- Estimated price
- €16–35
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 6m
- Frequency
- Hourly
- Estimated price
- €45–95
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 1h 51m
- Frequency
- Every 3 hours
- Estimated price
- €13–26
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Como S. Giovanni to Zürich HB
- Ave. Duration
- 2h 36m
- Frequency
- Hourly
- Estimated price
- €60–90
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39 0362 185 0590
- info@onebus.it
- Website
- Onebus
Bus from Como to Mühlheim am Main
- Ave. Duration
- 5h 32m
- Frequency
- Once a week
- Estimated price
- €80–110
- Website
- Onebus
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Zurich Bus Station to Mainz central train station
- Ave. Duration
- 8h 5m
- Frequency
- 5 times a week
- Estimated price
- €35–60
- Website
- Flixbus
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Booking & Getting There
Como to Mainz bus services, operated by Onebus, arrive at Mühlheim am Main station.
Como to Mainz train services, operated by Trenitalia EuroCity, arrive at Mannheim Hbf station.
Yes, the driving distance between Como to Mainz is 619 km. It takes approximately 5h 47m to drive from Como to Mainz.
Book your Como to Mainz train tickets online with Omio.
There are 1220+ hotels available in Mainz.

































