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How to get fromIstanbul to Sienaby bus, plane, train, night train or car

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There are 12 ways to get from Istanbul to Siena by bus, plane, train, night train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Istanbul, fly to Florence Peretola Airport, train

    best
    1. Take the bus from Istanbul Otogari to Istanbul Airport Busbus
    2. Fly from Istanbul (IST) to Florence Peretola Airport (FLR)planeIST - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain
    10h 48m
    €122–258

  2. Fly Istanbul Sabiha Gökçen International Airport to Fiumicino International Airport, train

    cheapest
    1. Fly from Istanbul Sabiha Gökçen International Airport (SAW) to Fiumicino International Airport (FCO)planeSAW - FCO
    2. Take the train from Roma Termini to Florence Santa Maria Novellatrain
    3. Take the train from Firenze S.M.N. to Sienatrain
    10h 51m
    €102–296

  3. Bus

    1. Take the bus from Istanbul to Kumanovobus
    2. Take the bus from Kumanovo to Sienabus
    31h 17m
    €132–154

  4. Night train, train

    1. Take the night train from Halkali to Bucharestnighttrain
    2. Take the night train from Bucuresti Nord to Wien Hbfnighttrain
    3. Take the train from Wien Hbf to Venezia MestretrainRjx
    4. Take the train from Venezia Mestre to Firenze S.M.N.trainFr
    5. Take the train from Firenze S.M.N. to SienatrainRe
    42h 48m
    €222–341

  5. Drive 1,990 km

    1. Drive from Istanbul to Sienacar1,990 km
    18h 36m
    €307–443

  6. Fly Istanbul Sabiha Gökçen International Airport to Florence Peretola Airport, train

    1. Fly from Istanbul Sabiha Gökçen International Airport (SAW) to Florence Peretola Airport (FLR)planeSAW - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain
    10h 50m
    €139–292

  7. Bus to Istanbul, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the bus from Istanbul Otogari to Istanbul Airport Busbus
    2. Fly from Istanbul (IST) to Bologna Guglielmo Marconi Airport (BLQ)planeIST - BLQ
    3. Take the train from Bologna Centrale to Florence Santa Maria Novellatrain
    4. Take the train from Firenze S.M.N. to Sienatrain
    9h 25m
    €121–280

  8. Fly Istanbul Sabiha Gökçen International Airport to Bologna Guglielmo Marconi Airport, train

    1. Fly from Istanbul Sabiha Gökçen International Airport (SAW) to Bologna Guglielmo Marconi Airport (BLQ)planeSAW - BLQ
    2. Take the train from Bologna Centrale to Florence Santa Maria Novellatrain
    3. Take the train from Firenze S.M.N. to Sienatrain
    9h 26m
    €128–294

  9. Bus to Istanbul, fly to Venice Marco Polo Airport, train

    1. Take the bus from Istanbul Otogari to Istanbul Airport Busbus
    2. Fly from Istanbul (IST) to Venice Marco Polo Airport (VCE)planeIST - VCE
    3. Take the train from Venezia Mestre to Firenze S.M.N.train
    4. Take the train from Firenze S.M.N. to Sienatrain
    11h 26m
    €127–321

  10. Bus to Istanbul, fly to Fiumicino International Airport, train

    1. Take the bus from Istanbul Otogari to Istanbul Airport Busbus
    2. Fly from Istanbul (IST) to Fiumicino International Airport (FCO)planeIST - FCO
    3. Take the train from Roma Termini to Florence Santa Maria Novellatrain
    4. Take the train from Firenze S.M.N. to Sienatrain
    10h 54m
    €115–282

  11. Bus via Pristina

    1. Take the bus from Instabul to Pristinabus
    2. Take the bus from Pristina to Sienabus
    31h 33m

  12. Train, bus

    1. Take the train from Halkalı to Sofiatrain
    2. Take the bus from Sofia to Firenze Autostazionebus
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus131
    40h 57m

Istanbul (IST) to Florence Peretola Airport (FLR) flights

Calendar29Weekly Planes
Duration6h 31mAverage Duration
Ticket€99Cheapest Price
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Questions & Answers

What companies run services between Istanbul, Turkey and Siena, Italy?

You can take a bus from Istanbul to Siena via Kumanovo in around 31h 17m.

Airlines
Train operators
Bus operators

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