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How to get fromLexington to St. Louisby car, plane or bus (Greyhound)

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There are 4 ways to get from Lexington to St. Louis by car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Louisville International Airport, fly

    best
    1. Drive from Lexington to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Lambert–St. Louis International Airport (STL)plane plane SDF - STL
    5h 43m
    $127–724

  2. Drive 337.6 mi

    cheapest
    1. Drive from Lexington to St. Louiscar car 337.6 mi
    5h 45m
    $62–89

  3. Bus (Greyhound)

    1. Take the bus from Lexington Bus Stop to Indianapolis Union Stationbus bus Greyhound US0120
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    11h 28m
    $71–151

  4. Fly from Blue Grass Airport

    1. Fly from Blue Grass Airport (LEX) to Lambert–St. Louis International Airport (STL)plane plane LEX - STL
    7h 44m
    $135–805

Lexington to St. Louis by bus (Greyhound)

Calendar7Weekly Buses
Duration11h 28mAverage Duration
Ticket$71Cheapest Price
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Questions & Answers

What companies run services between Lexington, KY, USA and St. Louis, MO, USA?

You can take a bus from Tates Creek @ Dove Run to St Louis Bus Station via Transit Center, Walmart @ Northpark, Lexington Bus Stop, and Indianapolis Union Station in around 11h 28m. Alternatively, American Airlines, Delta, and United Airlines fly from Blue Grass Airport (LEX) to Lambert–St. Louis International Airport (STL) every 2 hours.

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