Rome2Rio

How to get fromIndiana to St. Louisby bus (Greyhound), train (Amtrak), car, train or plane

Find Transport to St. Louis

See all options

There are 5 ways to get from Indiana to St. Louis by bus (Greyhound), train (Amtrak), car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Indianapolis Union Station to St Louis Bus StationbusGreyhound US0421
    3h 55m
    $35–120

  2. Train (Amtrak)

    1. Take the train from Indianapolis to Chicago Union StationtrainCardinal
    2. Take the train from Chicago Union Station to St. LouistrainLincoln Service / ...
    10h 46m
    $76–547

  3. Drive 241.8 mi

    1. Drive from Indianapolis to St. Louiscar241.8 mi
    4h
    $45–64

  4. Train to Chicago Midway International Airport, fly

    1. Take the train from Gary to Museum Campus/11th Street Sationtrain
    2. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)planeMDW - STL
    4h 26m
    $87–566

  5. Train to Chicago O'Hare International Airport, fly

    1. Take the train from Gary to Van Buren St.train
    2. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)planeORD - STL
    4h 53m
    $183–516

Indiana to St. Louis by bus (Greyhound)

Calendar21Weekly Buses
Duration3h 55mAverage Duration
Ticket$35Cheapest Price
See schedules

Questions & Answers

What companies run services between Indiana, USA and St. Louis, MO, USA?

Greyhound USA operates a bus from Indianapolis Union Station to St Louis Bus Station 3 times a day. Tickets cost $35–120 and the journey takes 3h 55m. Alternatively, you can take a train from Indianapolis to St. Louis via Chicago Union Station in around 10h 46m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Trips from Indiana

Trips to St. Louis

Popular routes