There are 9 ways to get from Keystone to Florida Keys by plane, bus, bus (Greyhound), train, car, shuttle, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Tampa to Key West International Airport, bus
best- Fly from Tampa (TPA) to Key West International Airport (EYW)plane TPA - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus
4h 43m$181–594Drive 400.6 mi
cheapest- Drive from Keystone to Florida Keyscar 400.6 mi
8h$74–106Bus
- Take the bus from Tampa International Airport to Miami Airportbus Tampa
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
12h 3m$150–253Train, bus
- Take the train from Tampa to Delray Beach Amtraktrain
- Take the train from Delray Beach Station to Miami Airport Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
12h 54m$153–260Fly Saint Petersburg–Clearwater International Airport to Key West International Airport, bus
- Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane PIE - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus
4h 30m$165–384Fly Tampa to Miami International Airport, shuttle
- Fly from Tampa (TPA) to Miami International Airport (MIA)plane TPA - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
7h 10m$341–664Fly Tampa to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Tampa (TPA) to Fort Lauderdale–Hollywood International Airport (FLL)plane TPA - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
7h 37m$286–774Bus, shuttle
- Take the bus from Tampa Bus Station to Miami Airport Stationbus FlixBus 2421 / ...
- Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine LabTo the Keys
14h 21m$227–320Bus via Marion Transit Center
- Take the bus from Tampa Bus Station to Miami Airport Stationbus FlixBus 2421 / ...
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
14h 43m$97–180
Tampa (TPA) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Keystone to Florida Keys is to drive which costs $70 - $110 and takes 8h.
The fastest way to get from Keystone to Florida Keys is to fly and bus which takes 4h 30m and costs $160 - $390.
The distance between Keystone and Florida Keys is 285 miles. The road distance is 403 miles.
The best way to get from Keystone to Florida Keys without a car is to bus which takes 12h 3m and costs $150 - $260.
It takes approximately 4h 43m to get from Keystone to Florida Keys, including transfers.
Yes, the driving distance between Keystone to Florida Keys is 403 miles. It takes approximately 8h to drive from Keystone to Florida Keys.
There are 498+ hotels available in Florida Keys.
What companies run services between Keystone, FL, USA and Florida Keys, FL, USA?
You can take a vehicle from Keystone to Florida Keys via Tampa International Airport, Miami Airport, Miami International Airport, Miami, Airport Intermodal Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 12h 3m.
- Website
- aa.com
Flights from Tampa to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 7m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $30–230
Flights from Tampa to Miami International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $30–230
- Website
- flybreeze.com
Flights from Tampa to Key West International Airport
- Ave. Duration
- 1h 18m
- When
- Thursday, Sunday, Monday, Wednesday, Friday, and Tuesday
- Estimated price
- $40–280
Flights from Tampa to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 9m
- When
- Wednesday and Saturday
- Estimated price
- $110–650
- Website
- allegiantair.com
Flights from Saint Petersburg–Clearwater International Airport to Key West International Airport
- Ave. Duration
- 1h 3m
- When
- Saturday, Thursday, Sunday, Monday, Friday, and Wednesday
- Estimated price
- $29–220
- Website
- southwest.com
Flights from Tampa to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 8m
- When
- Every day
- Estimated price
- $30–260
- Website
- jetblue.com
Flights from Tampa to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 4m
- When
- Every day
- Estimated price
- $30–260
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Tampa to Delray Beach Amtrak
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $60–130
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800-874-7245
- Tri-RailCustomerExperience@sfrta.fl.gov
- Website
- tri-rail.com
Train from Delray Beach Station to Miami Airport Station
- Ave. Duration
- 1h 24m
- Frequency
- Hourly
- Estimated price
- $5–9
- Website
- https://www.tri-rail.com
- Weekend | Holiday
- $5
- Weekday
- $6–9
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge
- Ave. Duration
- 36 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Tampa International Airport to Miami Airport
- Ave. Duration
- 5h 15m
- Frequency
- 5 times a week
- Estimated price
- $70–140
- Website
- https://www.redcoachusa.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
Bus from Tampa Bus Station to Miami Airport Station
- Ave. Duration
- 8h
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- https://www.keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- https://www.keysshuttle.com
Shuttle from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- https://www.keysshuttle.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Tampa Bus Station to Miami Airport Station
- Ave. Duration
- 6h
- Frequency
- 5 times a day
- Estimated price
- $35–65
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide















