There are 4 ways to get from Springfield to Florida Keys by plane, bus (Greyhound, Flixbus), car, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Key West International Airport
best- Fly from Springfield-Branson National Airport (SGF) to Key West International Airport (EYW)SGF - EYW
8h 32m$153–558Bus
- Take the bus from Springfield CU Transit Center to St Louis Bus Station
- Take the bus from St Louis Bus Station to Atlanta Bus Station
- Take the bus from Atlanta Bus Station to Miami Airport Station
- Take the bus from Miami Airport Station to Big Pine Key
36h 45m$177–344Drive 1,378.2 mi
- Drive from Springfield to Florida Keys1,378.2 mi
25h 25m$252–364Fly to Miami International Airport, shuttle
- Fly from Springfield-Branson National Airport (SGF) to Miami International Airport (MIA)SGF - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
8h 40m$223–593
Springfield to Florida Keys by bus and foot
Questions & Answers
The cheapest way to get from Springfield to Florida Keys is to bus which costs $170 - $350 and takes 36h 45m.
The fastest way to get from Springfield to Florida Keys is to fly which takes 8h 32m and costs $150 - $600.
No, there is no direct bus from Springfield to Florida Keys. However, there are services departing from Springfield CU Transit Center and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via St Louis Bus Station, Atlanta Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 36h 45m.
The distance between Springfield and Florida Keys is 1149 miles. The road distance is 1386.2 miles.
The best way to get from Springfield to Florida Keys without a car is to bus which takes 36h 45m and costs $170 - $350.
It takes approximately 8h 32m to get from Springfield to Florida Keys, including transfers.
Springfield to Florida Keys bus services, operated by Greyhound USA, depart from Springfield CU Transit Center station.
The best way to get from Springfield to Florida Keys is to fly which takes 8h 32m and costs $150 - $600. Alternatively, you can bus, which costs $170 - $350 and takes 36h 45m.
Springfield to Florida Keys bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Yes, the driving distance between Springfield to Florida Keys is 1386 miles. It takes approximately 25h 25m to drive from Springfield to Florida Keys.
What companies run services between Springfield, MO, USA and Florida Keys, FL, USA?
American Airlines, United Airlines, and Delta fly from Springfield-Branson National Airport (SGF) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Springfield CU Transit Center to Florida Keys via St Louis Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 36h 45m.
- Website
- aa.com
Flights from Springfield-Branson National Airport to Key West International Airport via Miami International Airport
- Ave. Duration
- 5h 27m
- When
- Saturday
- Estimated price
- $95–470
Flights from Springfield-Branson National Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $100–550
Flights from Springfield-Branson National Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 51m
- When
- Every day
- Estimated price
- $100–550
Flights from Springfield-Branson National Airport to Key West International Airport via Chicago O'Hare
- Ave. Duration
- 8h 25m
- When
- Thursday to Sunday
- Estimated price
- $120–550
Flights from Springfield-Branson National Airport to Miami International Airport
- Ave. Duration
- 2h 56m
- When
- Saturday
- Estimated price
- $75–390
Flights from Springfield-Branson National Airport to Miami International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 29m
- When
- Every day
- Estimated price
- $95–450
Flights from Springfield-Branson National Airport to Miami International Airport via Charlotte
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $85–430
- Website
- delta.com
Flights from Springfield-Branson National Airport to Key West International Airport via Atlanta
- Ave. Duration
- 7h
- When
- Every day
- Estimated price
- $90–470
Flights from Springfield-Branson National Airport to Miami International Airport via Atlanta
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $80–400
- Website
- united.com
Flights from Springfield-Branson National Airport to Key West International Airport via Chicago O'Hare
- Ave. Duration
- 6h 19m
- When
- Every day
- Estimated price
- $120–550
Flights from Springfield-Branson National Airport to Key West International Airport via Houston
- Ave. Duration
- 8h 33m
- When
- Every day
- Estimated price
- $100–550
Flights from Springfield-Branson National Airport to Miami International Airport via Houston
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $95–450
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Springfield CU Transit Center to St Louis Bus Station
- Ave. Duration
- 4h 5m
- Frequency
- Twice daily
- Estimated price
- $30–55
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 14h 5m
- Frequency
- Twice daily
- Estimated price
- $65–170
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $21–29
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h 30m
- Frequency
- 5 times a week
- Estimated price
- $55–90
- Schedules at
- flixbus.com
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 4 times a day
- Estimated price
- $130–180
- Website
- https://www.keysshuttle.com
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There are 118+ hotels available in Florida Keys.





