There are 5 ways to get from Kentucky to Tupelo by bus (Greyhound, Amtrak, Flixbus), car, bus, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Nashville
best- Take the bus from Louisville Bus Station to Nashville Bus Stationbus
- Take the bus from Nashville Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
10h 4m$82–137Drive 369.1 mi
cheapest- Drive from Louisville to Tupelocar 369.1 mi
7h 19m$68–98Bus, fly to Birmingham–Shuttlesworth International Airport, drive
- Take the bus from Louisville Bus Station to Nashville Bus Stationbus
- Fly from Nashville (BNA) to Birmingham–Shuttlesworth International Airport (BHM)plane BNA - BHM
- Drive from Birmingham-Airport-BHM to Tupelocar
7h 55m$142–785Bus
- Take the bus from La Tropicana - Louisville, KY to Tornado Bus Co - West Memphisbus Indianapolis
- Take the bus from Memphis Bus Station to Tupelobus Greyhound US0610
13h 30m$132–171Bus, fly to Memphis
- Take the bus from Louisville Bus Station to Nashville Bus Stationbus
- Fly from Nashville (BNA) to Memphis (MEM)plane BNA - MEM
- Take the bus from Memphis Bus Station to Tupelobus
9h 46m$535–885
Nashville (BNA) to Birmingham–Shuttlesworth International Airport (BHM) flights
Comparing Your Travel Options
The cheapest way to get from Kentucky to Tupelo is to drive which costs $65 - $100 and takes 7h 19m.
The fastest way to get from Kentucky to Tupelo is to drive which takes 7h 19m and costs $65 - $100.
No, there is no direct bus from Kentucky station to Tupelo. However, there are services departing from Louisville Bus Station and arriving at Tupelo via Nashville Bus Station and Memphis Bus Station. The journey, including transfers, takes approximately 10h 4m.
The distance between Kentucky and Tupelo is 491 miles. The road distance is 371.3 miles.
The best way to get from Kentucky to Tupelo without a car is to bus via Nashville which takes 10h 4m and costs $80 - $140.
It takes approximately 10h 4m to get from Kentucky to Tupelo, including transfers.
Kentucky to Tupelo bus services, operated by Greyhound USA, depart from Louisville Bus Station.
Kentucky to Tupelo bus services, operated by Greyhound USA, arrive at Nashville Bus Station.
Tupelo is 1h behind Kentucky. It is currently 12:41 PM in Kentucky and 11:41 AM in Tupelo.
Yes, the driving distance between Kentucky to Tupelo is 371 miles. It takes approximately 7h 19m to drive from Kentucky to Tupelo.
What companies run services between Kentucky, USA and Tupelo, MS, USA?
You can take a bus from Louisville Bus Station to Tupelo via Nashville Bus Station, Memphis Bus Station, and Tupelo in around 10h 4m.
- Website
- southwest.com
Flights from Nashville to Birmingham–Shuttlesworth International Airport
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- $90–700
Flights from Nashville to Memphis
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $95–700
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Louisville Bus Station to Nashville Bus Station
- Ave. Duration
- 2h 55m
- Frequency
- Every 4 hours
- Estimated price
- $27–45
- Website
- Greyhound
Bus from Nashville Bus Station to Memphis Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- 4 times a day
- Estimated price
- $30–55
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $15–25
- Website
- Greyhound
Bus from Louisville Bus Station to Nashville Bus Station
- Ave. Duration
- 2h 55m
- Frequency
- Every 4 hours
- Estimated price
- $27–45
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $15–25
- Website
- Greyhound
Bus from Louisville Bus Station to Nashville Bus Station
- Ave. Duration
- 2h 55m
- Frequency
- Every 4 hours
- Estimated price
- $27–45
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $15–25
- Website
- Greyhound
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Booking & Getting There
There are 34+ hotels available in Tupelo.


