There are 5 ways to get from Mobile to Tupelo by plane, car, bus (Greyhound), train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, drive
best- Fly from Mobile Regional Airport (MOB) to Golden Triangle Regional Airport (GTR)plane MOB - GTR
- Drive from Golden Triangle Regional Airport (GTR) to Tupelocar
6h 21m$103–424Drive 274.5 mi
cheapest- Drive from Mobile to Tupelocar 274.5 mi
5h 25m$51–73Bus (Greyhound)
- Take the bus from Mobile Bus Station to Atlanta Bus Stationbus Greyhound US0602 / ...
- Take the bus from Atlanta Bus Station to Tupelobus Greyhound US0610
13h 47m$103–165Train, bus
- Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Jacksontrain
- Take the bus from Jackson to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
15h 36m$131–282Bus via Mobile
- Take the bus from Mobile to Atlantabus Houston
- Take the bus from Atlanta Bus Station to Tupelobus Greyhound US0610
14h 14m$163–231
Mobile Regional Airport (MOB) to Golden Triangle Regional Airport (GTR) flights
Comparing Your Travel Options
The cheapest way to get from Mobile to Tupelo is to drive which costs $50 - $75 and takes 5h 25m.
The fastest way to get from Mobile to Tupelo is to drive which takes 5h 25m and costs $50 - $75.
No, there is no direct bus from Mobile to Tupelo. However, there are services departing from Govt WB and Joachim St and arriving at Tupelo via Mobile Bus Station and Atlanta Bus Station. The journey, including transfers, takes approximately 13h 47m.
The distance between Mobile and Tupelo is 269 miles. The road distance is 276.1 miles.
The best way to get from Mobile to Tupelo without a car is to bus which takes 13h 47m and costs $100 - $170.
It takes approximately 6h 21m to get from Mobile to Tupelo, including transfers.
Mobile to Tupelo bus services, operated by Greyhound USA, depart from Mobile Bus Station.
Mobile to Tupelo bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Yes, the driving distance between Mobile to Tupelo is 276 miles. It takes approximately 5h 25m to drive from Mobile to Tupelo.
Book your Mobile to Tupelo bus tickets online with Omio.
What companies run services between Mobile, AL, USA and Tupelo, MS, USA?
You can take a bus from Govt WB and Joachim St to Tupelo via Govt WB Across from Greyhound, Mobile Bus Station, Atlanta Bus Station, and Tupelo in around 13h 47m.
- Website
- delta.com
Flights from Mobile Regional Airport to Golden Triangle Regional Airport via Atlanta
- Ave. Duration
- 6h 52m
- When
- Every day
- Estimated price
- $60–370
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Mobile, AL to New Orleans, LA - Union Passenger Terminal
- Ave. Duration
- 3h 43m
- Frequency
- Twice daily
- Estimated price
- $30–80
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Jackson
- Ave. Duration
- 3h 39m
- Frequency
- Once daily
- Estimated price
- $45–110
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Mobile Bus Station to Atlanta Bus Station
- Ave. Duration
- 5h 35m
- Frequency
- 5 times a day
- Estimated price
- $50–85
- Website
- Greyhound
Bus from Atlanta Bus Station to Tupelo
- Ave. Duration
- 5h 55m
- Frequency
- Twice daily
- Estimated price
- $40–70
- Website
- Greyhound
Bus from Jackson to Memphis Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $30–55
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $15–25
- Website
- Greyhound
Bus from Atlanta Bus Station to Tupelo
- Ave. Duration
- 5h 55m
- Frequency
- Twice daily
- Estimated price
- $40–70
- Website
- Greyhound
Want to know more about travelling around United States
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Booking & Getting There
There are 34+ hotels available in Tupelo.





