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How to get fromIrvine to Lexingtonby plane, car, bus (Greyhound), train or bus

Find Transport to Lexington

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There are 6 ways to get from Irvine to Lexington by plane, car, bus (Greyhound), train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Louisville International Airport, drive

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Louisville International Airport (SDF)plane plane SNA - SDF
    2. Drive from Louisville-Airport-SDF to Lexingtoncar car
    6h 59m
    $204–828

  2. Fly to Blue Grass Airport

    cheapest
    1. Fly from John Wayne Airport Orange County (SNA) to Blue Grass Airport (LEX)plane plane SNA - LEX
    8h 37m
    $142–593

  3. Bus (Greyhound)

    1. Take the bus from Anaheim to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Lexington Bus Stopbus bus
    2d 6h
    $232–579

  4. Train, bus

    1. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Lexington Bus Stopbus bus
    2d 7h
    $262–1,784

  5. Drive 2,145.7 mi

    1. Drive from Irvine to Lexingtoncar car 2,145.7 mi
    34h 29m
    $392–566

  6. Train, bus via St. Louis

    1. Take the train from Pomona Amtrak to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Lexington Bus Stopbus bus
    2d 22h
    $282–821

John Wayne Airport Orange County (SNA) to Louisville International Airport (SDF) flights

Calendar66Weekly Planes
Duration7h 10mAverage Duration
Ticket$189Cheapest Price
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Questions & Answers

What companies run services between Irvine, CA, USA and Lexington, KY, USA?

You can take a bus from Main-Harvard to Lexington via Artic - Dock 4, Anaheim, Los Angeles Union Station, St Louis Bus Station, Indianapolis Union Station, and Lexington Bus Stop in around 2d 6h. Alternatively, United Airlines, American Airlines, and Delta fly from John Wayne Airport Orange County (SNA) to Blue Grass Airport (LEX) every 4 hours.

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Need to know: Greyhound

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