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How to get fromMyrtle Beach to Lexingtonby plane, car, bus or taxi

Find Transport to Lexington

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There are 4 ways to get from Myrtle Beach to Lexington by plane, car, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly, drive

    best
    1. Fly from Myrtle Beach (MYR) to Louisville International Airport (SDF)plane plane MYR - SDF
    2. Drive from Louisville-Airport-SDF to Lexingtoncar car
    3h 13m
    $174–483
  2. Drive 542.9 mi

    cheapest
    1. Drive from Myrtle Beach to Lexingtoncar car 542.9 mi
    10h 53m
    $100–144
  3. Bus, drive

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Evansville Bus Stationbus bus
    4. Take the bus from Evansville, IN to Corydon, INbus bus
    5. Drive from Middletown Station @ Target to Lexingtoncar car
    24h 58m
    $217–345
  4. Bus, taxi, drive

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Bloomingtonbus bus
    3. Take the bus from Bloomington, IN to Paoli Walmartbus bus
    4. Take the taxi from Paoli Walmart to Indiana University Southeasttaxi taxi
    5. Drive from Middletown Station @ Target to Lexingtoncar car
    28h 14m
    $247–391

Myrtle Beach (MYR) to Louisville International Airport (SDF) flights

Calendar25Weekly Planes
Duration3h 38mAverage Duration
Ticket$82Cheapest Price
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Questions & Answers

What companies run services between Myrtle Beach, SC, USA and Lexington, KY, USA?

There is no direct connection from Myrtle Beach to Lexington. However, you can take the taxi to Myrtle Beach (MYR) airport, fly to Louisville International Airport (SDF), then drive to Lexington. Alternatively, you can take a bus from Myrtle Beach Bus Station to Lexington via Atlanta Bus Station, Nashville Bus Station, Evansville, IN, Corydon, IN, S 5th @ W Jefferson, and Middletown Station @ Target in around 24h 58m.

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