What is the cheapest way to get from Myrtle Beach to Lexington?

The cheapest way to get from Myrtle Beach to Lexington is to drive which costs $95 - $150 and takes 10h 53m.

What is the fastest way to get from Myrtle Beach to Lexington?

The fastest way to get from Myrtle Beach to Lexington is to fly and drive which takes 3h 13m and costs $160 - $490.

How far is it from Myrtle Beach to Lexington?

The distance between Myrtle Beach and Lexington is 578 miles. The road distance is 546 miles.

How long does it take to get from Myrtle Beach to Lexington?

It takes approximately 3h 13m to get from Myrtle Beach to Lexington, including transfers.

Can I drive from Myrtle Beach to Lexington?

Yes, the driving distance between Myrtle Beach to Lexington is 546 miles. It takes approximately 10h 53m to drive from Myrtle Beach to Lexington.

Where can I stay near Lexington?

There are 140+ hotels available in Lexington.

Myrtle Beach to Lexington - 4 ways to travel via plane, car, bus

There are 4 ways to get from Myrtle Beach to Lexington by plane, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly to Louisville International Airport, drive
best
1. Fly from Myrtle Beach (MYR) to Louisville International Airport (SDF)plane MYR - SDF
2. Drive from Louisville-Airport-SDF to Lexingtoncar
3h 13m
$164–483
Fly to Blue Grass Airport, line 3 bus
cheapest
1. Fly from Myrtle Beach (MYR) to Blue Grass Airport (LEX)plane MYR - LEX
2. Take the bus from Transit Center to Centre Parkway @ 1349bus
3h 57m
$62–344
Bus, drive
1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus
2. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus
3. Take the bus from Nashville Bus Station to Evansville Bus Stationbus
4. Take the bus from Evansville, IN to Corydon, INbus
5. Drive from Middletown Station @ Target to Lexingtoncar
24h 58m
$218–385
Drive 542.9 mi
1. Drive from Myrtle Beach to Lexingtoncar 542.9 mi
10h 53m
$100–144

Myrtle Beach (MYR) to Louisville International Airport (SDF) flights

15Weekly Planes

3h 13mAverage Duration

$80Cheapest Price

See schedules

Questions & Answers

Map of how to get from Myrtle Beach to Lexington.

Launch map view

Distance: 574.3 mi
Duration: 3h 13m

What companies run services between Myrtle Beach, SC, USA and Lexington, KY, USA?

There is no direct connection from Myrtle Beach to Lexington. However, you can take the taxi to Myrtle Beach (MYR) airport, fly to Louisville International Airport (SDF), then drive to Lexington. Alternatively, you can take a bus from Myrtle Beach Bus Station to Lexington via Atlanta Bus Station, Nashville Bus Station, Evansville, IN, Corydon, IN, S 5th @ W Jefferson, and Middletown Station @ Target in around 24h 58m.

Airlines

Bus operators

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