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How to get fromIowa to Niagara Fallsby plane, bus, bus (Greyhound), train, car, or bus (Greyhound, Amtrak, Flixbus)

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There are 8 ways to get from Iowa to Niagara Falls by plane, bus, bus (Greyhound), train, car, or bus (Greyhound, Amtrak, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines, bus

    best
    1. Fly from Des Moines (DSM) to Buffalo Niagara International Airport (BUF)plane plane DSM - BUF
    2. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    5h 41m
    $182–879

  2. Fly from Quad City International Airport, bus

    cheapest
    1. Fly from Quad City International Airport (MLI) to Buffalo Niagara International Airport (BUF)plane plane MLI - BUF
    2. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    8h 9m
    $106–610

  3. Bus

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago to Clevelandbus bus
    3. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    20h 39m
    $109–247

  4. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    3. Take the train from Buffalo Depew Station to Canadian Bordertrain train
    21h 14m
    $229–477

  5. Drive 835.6 mi

    1. Drive from Des Moines to Niagara Fallscar car 835.6 mi
    13h 57m
    $153–221

  6. Fly from Omaha, bus

    1. Fly from Omaha (OMA) to Buffalo Niagara International Airport (BUF)plane plane OMA - BUF
    2. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    8h 19m
    $167–811

  7. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    4. Take the train from Buffalo Depew Station to Niagara Falls Amtrak Stationtrain train
    21h 54m
    $258–680

  8. Bus via Detroit

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Union Station to Detroitbus bus
    3. Take the bus from Detroit Bus Station to Torontobus bus
    4. Take the bus from Toronto Union Station to Niagara Falls, ONbus bus
    24h 16m
    $197–367

Des Moines (DSM) to Buffalo Niagara International Airport (BUF) flights

Calendar74Weekly Planes
Duration5h 20mAverage Duration
Ticket$160Cheapest Price
See schedules

Questions & Answers

Map of how to get from Iowa to Niagara Falls.ExpandLaunch map view
  • Distance: 806.2 mi
  • Duration: 5h 41m

What companies run services between Iowa, USA and Niagara Falls, NY, USA?

You can take a vehicle from Des Moines to Main Street & Pine Avenue via Des Moines, Chicago, Cleveland, OH, and Ellicott Street & MTC Static in around 20h 39m.

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Train operators
Bus operators

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