There are 8 ways to get from Iowa to Myrtle Beach by plane, bus (Greyhound, Flixbus, Amtrak), bus, train, car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Des Moines
best- Fly from Des Moines (DSM) to Myrtle Beach (MYR)plane DSM - MYR
4h 48m$159–685Fly from Quad City International Airport
cheapest- Fly from Quad City International Airport (MLI) to Myrtle Beach (MYR)plane MLI - MYR
6h 42m$88–396Bus via Carbondale
- Take the bus from Des Moines to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus
- Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus
29h 55m$187–395Bus, train via Galesburg
- Take the bus from Des Moines to Galesburgbus
- Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain
- Take the train from Petersburg Amtrak Station to Wilsontrain
- Take the bus from Wilson to Wilmington Amtrak Stationbus
- Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus
40h 5m$430–933Drive 1,183.1 mi
- Drive from Des Moines to Myrtle Beachcar 1,183.1 mi
21h 17m$216–312Fly from Omaha
- Fly from Omaha (OMA) to Myrtle Beach (MYR)plane OMA - MYR
7h 6m$134–617Bus
- Take the bus from Des Moines to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus
31h$189–410Bus, train
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Raleigh Union Stationtrain
- Take the bus from Raleigh Bus Station to Myrtle Beach Bus Stationbus
43h 39m$426–942
Des Moines (DSM) to Myrtle Beach (MYR) flights
Questions & Answers
The cheapest way to get from Iowa to Myrtle Beach is to fly which costs $85 - $400 and takes 6h 42m.
The fastest way to get from Iowa to Myrtle Beach is to fly which takes 4h 48m and costs $150 - $700.
The distance between Iowa and Myrtle Beach is 985 miles. The road distance is 1190 miles.
The best way to get from Iowa to Myrtle Beach without a car is to bus via Carbondale which takes 29h 55m and costs $180 - $400.
It takes approximately 4h 48m to get from Iowa to Myrtle Beach, including transfers.
The best way to get from Iowa to Myrtle Beach is to fly which takes 4h 48m and costs $150 - $700. Alternatively, you can bus via Carbondale, which costs $180 - $400 and takes 29h 55m.
Myrtle Beach is 1h ahead of Iowa. It is currently 11:31 AM in Iowa and 12:31 PM in Myrtle Beach.
Yes, the driving distance between Iowa to Myrtle Beach is 1190 miles. It takes approximately 21h 17m to drive from Iowa to Myrtle Beach.
There are 5589+ hotels available in Myrtle Beach.
What companies run services between Iowa, USA and Myrtle Beach, SC, USA?
Southwest Airlines, American Airlines, and two other airlines fly from Des Moines (DSM) to Myrtle Beach (MYR) every 4 hours. Alternatively, you can take a vehicle from Des Moines to Myrtle Beach Bus Station via Des Moines, St Louis Bus Station, Carbondale Intermodal Station, and Atlanta Bus Station in around 29h 55m.
- Website
- aa.com
Flights from Des Moines to Myrtle Beach via Charlotte
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $130–650
Flights from Des Moines to Myrtle Beach via Chicago O'Hare
- Ave. Duration
- 5h 47m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–650
Flights from Des Moines to Myrtle Beach via Reagan Washington
- Ave. Duration
- 7h 17m
- When
- Saturday
- Estimated price
- $160–750
Flights from Quad City International Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $75–380
Flights from Quad City International Airport to Myrtle Beach via Chicago O'Hare
- Ave. Duration
- 4h 47m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–400
Flights from Quad City International Airport to Myrtle Beach via Dallas/Ft.Worth
- Ave. Duration
- 6h 54m
- When
- Every day
- Estimated price
- $130–600
Flights from Omaha to Myrtle Beach via Charlotte
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $120–600
- Website
- southwest.com
Flights from Des Moines to Myrtle Beach via Chicago Midway
- Ave. Duration
- 4h 53m
- When
- Saturday, Monday, Thursday, and Friday
- Estimated price
- $130–650
Flights from Omaha to Myrtle Beach via Nashville
- Ave. Duration
- 4h 45m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $120–600
Flights from Omaha to Myrtle Beach via Chicago Midway
- Ave. Duration
- 4h 46m
- When
- Saturday to Wednesday
- Estimated price
- $130–650
Flights from Omaha to Myrtle Beach via St. Louis
- Ave. Duration
- 5h 47m
- When
- Sunday and Saturday
- Estimated price
- $120–600
- Website
- delta.com
Flights from Des Moines to Myrtle Beach via Minneapolis
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $160–750
Flights from Des Moines to Myrtle Beach via Atlanta
- Ave. Duration
- 6h 31m
- When
- Every day
- Estimated price
- $140–650
Flights from Quad City International Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 6h 33m
- When
- Every day
- Estimated price
- $85–410
Flights from Omaha to Myrtle Beach via Atlanta
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- $130–650
- Website
- united.com
Flights from Des Moines to Myrtle Beach via Chicago O'Hare
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $140–650
Flights from Quad City International Airport to Myrtle Beach via Chicago O'Hare
- Ave. Duration
- 4h 57m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $80–400
- Website
- allegiantair.com
Flights from Quad City International Airport to Myrtle Beach via St. Petersburg, Ashland
- Ave. Duration
- 7h 28m
- When
- Saturday
- Estimated price
- $160–650
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Galesburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $45–100
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Petersburg Amtrak Station
- Ave. Duration
- 21h 1m
- Frequency
- Once daily
- Estimated price
- $260–600
- Website
- https://www.amtrak.com/home.html
Train from Petersburg Amtrak Station to Wilson
- Ave. Duration
- 1h 49m
- Frequency
- Twice daily
- Estimated price
- $30–70
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Raleigh Union Station
- Ave. Duration
- 24h 1m
- Frequency
- Once daily
- Estimated price
- $310–700
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to St Louis Bus Station
- Ave. Duration
- 8h 15m
- Frequency
- Twice daily
- Estimated price
- $60–120
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 8h 40m
- Frequency
- Twice daily
- Estimated price
- $50–110
- Website
- https://www.greyhound.com/
Bus from Des Moines to Galesburg
- Ave. Duration
- 4h 45m
- Frequency
- Twice daily
- Estimated price
- $30–60
- Website
- https://www.greyhound.com/
Bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $11–23
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 12h
- Frequency
- Twice daily
- Estimated price
- $80–170
- Website
- https://www.greyhound.com/
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 5 times a day
- Estimated price
- $45–100
- Website
- https://www.greyhound.com/
Bus from Raleigh Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 9h 50m
- Frequency
- Twice daily
- Estimated price
- $60–130
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from St Louis Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $13–23
- Schedules at
- flixbus.com
Bus from Carbondale Intermodal Station to Atlanta Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- Once daily
- Estimated price
- $55–100
- Schedules at
- flixbus.com
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h
- Frequency
- Once daily
- Estimated price
- $70–120
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from St Louis Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- https://www.amtrak.com/home.html
Bus from Wilson to Wilmington Amtrak Station
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- $45–70
- Website
- https://www.amtrak.com/home.html
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide








