There are 7 ways to get from Iowa to Myrtle Beach by plane, bus (Greyhound, Flixbus), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Des Moines
best- Fly from Des Moines (DSM) to Myrtle Beach (MYR)plane DSM - MYR
4h 13m$110–437Fly from Quad City International Airport
cheapest- Fly from Quad City International Airport (MLI) to Myrtle Beach (MYR)plane MLI - MYR
7h 14m$83–396Bus
- Take the bus from Des Moines to Kansas Citybus
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus
30h 50m$253–402Bus, train via Galesburg
- Take the bus from Des Moines to Galesburgbus
- Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain
- Take the train from Petersburg Amtrak Station to Fayetteville Amtrak Stationtrain
- Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus
38h 45m$746–1,215Drive 1,183.6 mi
- Drive from Des Moines to Myrtle Beachcar 1,183.6 mi
21h 15m$203–293Fly from Waterloo Municipal Airport
- Fly from Waterloo Municipal Airport (ALO) to Myrtle Beach (MYR)plane ALO - MYR
6h 15m$111–448Bus, train
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Raleigh Union Stationtrain
- Take the bus from Raleigh Bus Station to Myrtle Beach Bus Stationbus
39h 33m$662–1,069
Iowa to Myrtle Beach by bus
Comparing Your Travel Options
The cheapest way to get from Iowa to Myrtle Beach is to fly which costs $80 - $400 and takes 7h 14m.
The fastest way to get from Iowa to Myrtle Beach is to fly which takes 4h 13m and costs $110 - $440.
No, there is no direct bus from Iowa to Myrtle Beach station. However, there are services departing from Des Moines and arriving at Myrtle Beach Bus Station via Kansas City Bus Station, St Louis Bus Station and Atlanta Bus Station. The journey, including transfers, takes approximately 30h 50m.
The distance between Iowa and Myrtle Beach is 985 miles. The road distance is 1190.5 miles.
The best way to get from Iowa to Myrtle Beach without a car is to bus which takes 30h 50m and costs $250 - $410.
It takes approximately 4h 13m to get from Iowa to Myrtle Beach, including transfers.
Iowa to Myrtle Beach bus services, operated by Jefferson Lines, depart from Des Moines station.
The best way to get from Iowa to Myrtle Beach is to fly which takes 4h 13m and costs $110 - $440. Alternatively, you can bus, which costs $250 - $410 and takes 30h 50m.
Iowa to Myrtle Beach bus services, operated by Jefferson Lines, arrive at Kansas City station.
Myrtle Beach is 1h ahead of Iowa. It is currently 2:53 AM in Iowa and 3:53 AM in Myrtle Beach.
What companies run services between Iowa, USA and Myrtle Beach, SC, USA?
Southwest Airlines, American Airlines, and Delta fly from Des Moines (DSM) to Myrtle Beach (MYR) every 4 hours. Alternatively, you can take a bus from Des Moines to Myrtle Beach Bus Station via Kansas City, Kansas City Bus Station, St Louis Bus Station, and Atlanta Bus Station in around 30h 50m.
- Website
- aa.com
Flights from Des Moines to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 45m
- When
- Monday, Tuesday, Wednesday, and Saturday
- Estimated price
- $80–400
Flights from Des Moines to Myrtle Beach via Reagan Washington
- Ave. Duration
- 5h 56m
- When
- Saturday
- Estimated price
- $95–450
Flights from Waterloo Municipal Airport to Myrtle Beach via Chicago O'Hare
- Ave. Duration
- 6h
- When
- Every day
- Estimated price
- $80–410
Flights from Quad City International Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $70–380
Flights from Quad City International Airport to Myrtle Beach via Chicago O'Hare
- Ave. Duration
- 5h 49m
- When
- Every day
- Estimated price
- $75–390
Flights from Quad City International Airport to Myrtle Beach via Dallas/Ft.Worth
- Ave. Duration
- 10h 1m
- When
- Every day
- Estimated price
- $120–550
- Website
- delta.com
Flights from Des Moines to Myrtle Beach via Atlanta
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- $85–420
Flights from Des Moines to Myrtle Beach via Minneapolis
- Ave. Duration
- 8h 44m
- When
- Every day
- Estimated price
- $100–460
Flights from Quad City International Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 6h 15m
- When
- Every day
- Estimated price
- $80–400
- Website
- southwest.com
Flights from Des Moines to Myrtle Beach via Nashville
- Ave. Duration
- 3h 55m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $80–410
Flights from Des Moines to Myrtle Beach via Chicago Midway
- Ave. Duration
- 5h 20m
- When
- Saturday
- Estimated price
- $85–410
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Galesburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $85–140
- Website
- Amtrak
Train from Chicago Union Station to Petersburg Amtrak Station
- Ave. Duration
- 21h 1m
- Frequency
- Once daily
- Estimated price
- $490–800
- Website
- Amtrak
Train from Petersburg Amtrak Station to Fayetteville Amtrak Station
- Ave. Duration
- 2h 54m
- Frequency
- Twice daily
- Estimated price
- $100–160
- Website
- Amtrak
Train from Chicago Union Station to Raleigh Union Station
- Ave. Duration
- 24h 1m
- Frequency
- Once daily
- Estimated price
- $550–900
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Kansas City Bus Station to St Louis Bus Station
- Ave. Duration
- 4h
- Frequency
- Every 4 hours
- Estimated price
- $45–70
- Website
- Greyhound
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Twice daily
- Estimated price
- $100–160
- Website
- Greyhound
Bus from Atlanta Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 8h 40m
- Frequency
- Twice daily
- Estimated price
- $65–100
- Website
- Greyhound
Bus from Des Moines to Galesburg
- Ave. Duration
- 4h 30m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Greyhound
Bus from Fayetteville Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $28–45
- Website
- Greyhound
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- 5 times a day
- Estimated price
- $60–95
- Website
- Greyhound
Bus from Raleigh Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 4h 35m
- Frequency
- Twice daily
- Estimated price
- $40–60
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h 10m
- Frequency
- Once daily
- Estimated price
- $90–140
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Yes, the driving distance between Iowa to Myrtle Beach is 1191 miles. It takes approximately 21h 15m to drive from Iowa to Myrtle Beach.
There are 5649+ hotels available in Myrtle Beach.












