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How to get fromIowa to Myrtle Beachby plane, bus (Greyhound, Amtrak, Flixbus), bus, train, car, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Iowa to Myrtle Beach by plane, bus (Greyhound, Amtrak, Flixbus), bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Myrtle Beach (MYR)plane plane DSM - MYR
    4h 35m
    $149–635

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Myrtle Beach (MYR)plane plane MLI - MYR
    6h 51m
    $83–376

  3. Bus

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St. Louis to Carbondalebus bus
    3. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    30h 10m
    $209–405

  4. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    4. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train
    5. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    41h 11m
    $503–1,048

  5. Drive 1,183.1 mi

    1. Drive from Des Moines to Myrtle Beachcar car 1,183.1 mi
    21h 17m
    $216–312

  6. Fly from Omaha

    1. Fly from Omaha (OMA) to Myrtle Beach (MYR)plane plane OMA - MYR
    6h 56m
    $114–507

  7. Bus via Kansas City

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    30h 50m
    $223–412

  8. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the bus from Raleigh Bus Station to Myrtle Beach Bus Stationbus bus
    44h 4m
    $466–937

Iowa to Myrtle Beach by bus

Calendar7Weekly Buses
Duration30h 50mAverage Duration
Ticket$223Cheapest Price
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Questions & Answers

Map of how to get from Iowa to Myrtle Beach.ExpandLaunch map view
  • Distance: 978.9 mi
  • Duration: 4h 35m

What companies run services between Iowa, USA and Myrtle Beach, SC, USA?

American Airlines, Southwest Airlines, and two other airlines fly from Des Moines (DSM) to Myrtle Beach (MYR) every 4 hours. Alternatively, you can take a vehicle from Des Moines to Myrtle Beach Bus Station via Des Moines, St Louis Bus Station, St. Louis, Carbondale Intermodal Station, and Atlanta Bus Station in around 30h 10m.

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Want to know more about travelling around United States

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