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How to get fromIowa to Myrtle Beachby plane, bus (Greyhound, Flixbus), bus, train, or car

Find Transport to Myrtle Beach

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There are 7 ways to get from Iowa to Myrtle Beach by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Myrtle Beach (MYR)plane plane DSM - MYR
    4h 48m
    $159–685

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Myrtle Beach (MYR)plane plane MLI - MYR
    6h 42m
    $88–396

  3. Bus

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    29h
    $189–410

  4. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    4. Take the train from Petersburg Amtrak Station to Wilsontrain train
    5. Take the bus from Wilson to Wilmington Amtrak Stationbus bus
    6. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus bus
    40h 5m
    $430–933

  5. Drive 1,183.1 mi

    1. Drive from Des Moines to Myrtle Beachcar car 1,183.1 mi
    21h 17m
    $216–312

  6. Fly from Omaha

    1. Fly from Omaha (OMA) to Myrtle Beach (MYR)plane plane OMA - MYR
    7h 6m
    $134–617

  7. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the bus from Raleigh Bus Station to Myrtle Beach Bus Stationbus bus
    43h 39m
    $426–942

Des Moines (DSM) to Myrtle Beach (MYR) flights

Calendar55Weekly Planes
Duration5h 36mAverage Duration
Ticket$131Cheapest Price
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Questions & Answers

Map of how to get from Iowa to Myrtle Beach.ExpandLaunch map view
  • Distance: 978.9 mi
  • Duration: 4h 48m

What companies run services between Iowa, USA and Myrtle Beach, SC, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Des Moines (DSM) to Myrtle Beach (MYR) every 4 hours. Alternatively, you can take a vehicle from Des Moines to Myrtle Beach Bus Station via Des Moines, St Louis Bus Station, and Atlanta Bus Station in around 29h.

Airlines
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Want to know more about travelling around United States

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