Rome2Rio

How to get fromIowa to Myrtle Beachby plane, bus (Greyhound, Flixbus), bus, train or car

Find Transport to Myrtle Beach

See all options

There are 7 ways to get from Iowa to Myrtle Beach by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Myrtle Beach (MYR)plane plane DSM - MYR
    4h 38m
    $148–684

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Myrtle Beach (MYR)plane plane MLI - MYR
    6h 36m
    $77–375

  3. Bus

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    32h 15m
    $209–440

  4. Bus, train via Raleigh

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the bus from Raleigh Bus Station to Wilmington Cape Fear Public Transitbus bus
    4. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus bus
    39h 23m
    $342–730

  5. Drive 1,183.1 mi

    1. Drive from Des Moines to Myrtle Beachcar car 1,183.1 mi
    21h 15m
    $216–312

  6. Fly from Omaha

    1. Fly from Omaha (OMA) to Myrtle Beach (MYR)plane plane OMA - MYR
    7h 26m
    $133–666

  7. Bus, train

    1. Take the bus from Des Moines to Iowa Citybus bus
    2. Take the bus from Iowa City to Chicago Bus Stationbus bus
    3. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    4. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train
    5. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    40h 50m
    $358–805

Des Moines (DSM) to Myrtle Beach (MYR) flights

Calendar40Weekly Planes
Duration5h 49mAverage Duration
Ticket$128Cheapest Price
See schedules

Questions & Answers

What companies run services between Iowa, USA and Myrtle Beach, SC, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Des Moines (DSM) to Myrtle Beach (MYR) every 4 hours. Alternatively, you can take a vehicle from Des Moines to Myrtle Beach Bus Station via Des Moines, Chicago Bus Station, and Atlanta Bus Station in around 32h 15m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Iowa

Trips to Myrtle Beach

Popular routes