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How to get fromIowa to Charlotteby plane, bus (Greyhound), bus, train, or car

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There are 8 ways to get from Iowa to Charlotte by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Charlotte Douglas International Airport (CLT)plane plane DSM - CLT
    3h 15m
    $211–974

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Charlotte Douglas International Airport (CLT)plane plane MLI - CLT
    5h 19m
    $115–605

  3. Bus via Columbus

    1. Take the bus from Des Moines to Indianapolisbus bus
    2. Take the bus from Indianapolis to Columbusbus bus
    3. Take the bus from Columbus - Mound St to Charlotte Bus Stationbus bus
    25h 33m

  4. Bus, train

    1. Take the bus from Des Moines to Chicagobus bus
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to Charlotte Amtrak Stationtrain train
    35h 43m

  5. Drive 1,029.4 mi

    1. Drive from Des Moines to Charlottecar car 1,029.4 mi
    17h 40m
    $188–272

  6. Fly from The Eastern Iowa Airport

    1. Fly from The Eastern Iowa Airport (CID) to Charlotte Douglas International Airport (CLT)plane plane CID - CLT
    4h 39m
    $240–1,171

  7. Bus

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Wilson & Ferrell Shell Station - Columbusbus bus
    3. Take the bus from Columbus to Charlottebus bus
    25h 59m

  8. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    4. Take the train from Raleigh Union Station to Charlotte Amtrak Stationtrain train
    37h 36m

Des Moines (DSM) to Charlotte Douglas International Airport (CLT) flights

Calendar74Weekly Planes
Duration4h 14mAverage Duration
Ticket$196Cheapest Price
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Questions & Answers

Map of how to get from Iowa to Charlotte.ExpandLaunch map view
  • Distance: 827.6 mi
  • Duration: 3h 15m

What companies run services between Iowa, USA and Charlotte, NC, USA?

American Airlines, Southwest Airlines, and two other airlines fly from Des Moines (DSM) to Charlotte Douglas International Airport (CLT) every 2 hours. Alternatively, you can take a bus from Des Moines to Charlotte Bus Station via Indianapolis, Indianapolis, Columbus, E Main St & S High St, S Grant Ave & E Mound St, and Columbus - Mound St in around 25h 33m.

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