Rome2Rio

How to get fromIowa to Charlotteby plane, bus (Flixbus, Greyhound), bus, train, car or bus (Greyhound)

Find Transport to Charlotte

See all options

There are 9 ways to get from Iowa to Charlotte by plane, bus (Flixbus, Greyhound), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Charlotte Douglas International Airport (CLT)plane plane DSM - CLT
    3h 18m
    $151–724

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Charlotte Douglas International Airport (CLT)plane plane MLI - CLT
    5h 27m
    $75–395

  3. Bus via Columbus

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis to Columbusbus bus
    3. Take the bus from Columbus - Mound St to Charlotte Bus Stationbus bus
    25h 34m
    $155–378

  4. Bus, train

    1. Take the bus from Des Moines to Chicagobus bus
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to Charlotte Amtrak Stationtrain train
    36h 43m
    $204–1,986

  5. Drive 1,029.4 mi

    1. Drive from Des Moines to Charlottecar car 1,029.4 mi
    17h 32m
    $188–272

  6. Fly from The Eastern Iowa Airport

    1. Fly from The Eastern Iowa Airport (CID) to Charlotte Douglas International Airport (CLT)plane plane CID - CLT
    4h 43m
    $100–443

  7. Bus

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Columbus Bus Stationbus bus
    3. Take the bus from Columbus Bus Station to Charlotte Bus Stationbus bus
    26h 55m
    $173–355

  8. Bus, train via 7Th St / Locust St, Dsm

    1. Take the bus from Des Moines to Chicagobus bus
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to Charlotte Amtrak Stationtrain train
    36h 56m
    $215–1,984

  9. Bus, train via Galesburg

    1. Take the bus from Des Moines to Burlingtonbus bus
    2. Take the bus from Burlington to Galesburgbus bus
    3. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Carytrain train
    5. Take the train from Cary to Charlotte Amtrak Stationtrain train
    38h 14m
    $235–2,039

Iowa to Charlotte by bus and foot

Calendar7Weekly Services
Duration25h 34mAverage Duration
Ticket$155Cheapest Price
See schedules

Questions & Answers

What companies run services between Iowa, USA and Charlotte, NC, USA?

American Airlines, Delta, and United Airlines fly from Des Moines (DSM) to Charlotte Douglas International Airport (CLT) every 3 hours. Alternatively, you can take a bus from Des Moines to Charlotte Bus Station via Indianapolis, Illinois St (Greyhound Bus Station), Indianapolis, Columbus, E Main St & S High St, S Grant Ave & E Mound St, and Columbus - Mound St in around 25h 34m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Trips from Iowa

Trips to Charlotte

Popular routes