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How to get fromIowa to Saint Charlesby plane, bus (Greyhound), bus, train or car

Find Transport to Saint Charles

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There are 4 ways to get from Iowa to Saint Charles by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL)plane plane DSM - STL
    2h 29m
    $182–1,125
  2. Drive 310.1 mi

    cheapest
    1. Drive from Des Moines to Saint Charlescar car 310.1 mi
    6h 19m
    $57–82
  3. Bus

    1. Take the bus from Des Moines to Kansas Citybus bus Jefferson 803 / ...
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus Greyhound US0136 / ...
    10h
    $66–164
  4. Bus, train

    1. Take the bus from Des Moines to Kansas Citybus bus Jefferson 803 / ...
    2. Take the train from Kansas City to St. Louistrain train Missouri River Runner / ...
    12h 11m
    $61–154

Des Moines (DSM) to Lambert–St. Louis International Airport (STL) flights

Calendar15Weekly Planes
Duration1h 16mAverage Duration
Ticket$159Cheapest Price
See schedules

Questions & Answers

What companies run services between Iowa, USA and Saint Charles, MO, USA?

Southwest Airlines flies from Des Moines (DSM) to Lambert–St. Louis International Airport (STL) twice daily. Alternatively, you can take a vehicle from Des Moines to 4375 Rider Trail North Sb via Des Moines, Kansas City Bus Station, St Louis Bus Station, CIVIC CENTER station, NORTH HANLEY station, and North Hanley Transit Center in around 10h.

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