There are 6 ways to get from Indianapolis to Key West by plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Indianapolis
best- Fly from Indianapolis (IND) to Key West International Airport (EYW)plane IND - EYW
4h 46m$133–665Bus
- Take the bus from Indianapolis to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
35h 6m$146–366Train, bus
- Take the train from Indianapolis to Alexandriatrain
- Take the train from Alexandria to Miami Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
2d 1h$299–734Drive 1,287.8 mi
- Drive from Indianapolis to Key Westcar 1,287.8 mi
23h 58m$235–340Bus to Covington, fly
- Take the bus from Indianapolis to Cincinnatibus
- Fly from Covington (CVG) to Key West International Airport (EYW)plane CVG - EYW
7h 15m$208–1,051Bus via Macon
- Take the bus from Indianapolis Union Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Macon Bus Stationbus
- Take the bus from Macon Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
37h 31m$159–411
Indianapolis to Key West by bus and foot
Questions & Answers
The cheapest way to get from Indianapolis to Key West is to bus via Macon which costs $150 - $420 and takes 37h 31m.
The fastest way to get from Indianapolis to Key West is to fly which takes 4h 46m and costs $130 - $700.
No, there is no direct bus from Indianapolis to Key West. However, there are services departing from Indianapolis and arriving at N Roosevelt & 3rd Street via Atlanta Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 35h 6m.
The distance between Indianapolis and Key West is 1104 miles. The road distance is 1295.3 miles.
The best way to get from Indianapolis to Key West without a car is to bus which takes 35h 6m and costs $140 - $370.
It takes approximately 4h 46m to get from Indianapolis to Key West, including transfers.
Indianapolis to Key West bus services, operated by Flixbus USA, depart from Indianapolis station.
The best way to get from Indianapolis to Key West is to fly which takes 4h 46m and costs $130 - $700. Alternatively, you can bus, which costs $140 - $370 and takes 35h 6m.
Indianapolis to Key West bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Yes, the driving distance between Indianapolis to Key West is 1295 miles. It takes approximately 23h 58m to drive from Indianapolis to Key West.
What companies run services between Indianapolis, IN, USA and Key West, FL, USA?
Allegiant Air, Delta, and Spirit Airlines fly from Indianapolis (IND) to Key West International Airport (EYW) 5 times a day. Alternatively, you can take a bus from Indianapolis to N Roosevelt & 3rd Street via Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 35h 6m.
- Website
- delta.com
Flights from Indianapolis to Key West International Airport via Atlanta
- Ave. Duration
- 5h 47m
- When
- Every day
- Estimated price
- $130–700
Flights from Covington to Key West International Airport via Atlanta
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $180–950
- Website
- allegiantair.com
Flights from Indianapolis to Key West International Airport
- Ave. Duration
- 2h 55m
- When
- Thursday and Sunday
- Estimated price
- $130–700
Flights from Covington to Key West International Airport
- Ave. Duration
- 2h 51m
- When
- Monday and Friday
- Estimated price
- $180–950
Flights from Covington to Key West International Airport via St. Petersburg
- Ave. Duration
- 6h 32m
- When
- Monday and Friday
- Estimated price
- $180–950
- Website
- spirit.com
Flights from Indianapolis to Key West International Airport via Fort Lauderdale
- Ave. Duration
- 6h 46m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Indianapolis to Alexandria
- Ave. Duration
- 18h 12m
- Frequency
- 3 times a week
- Estimated price
- $140–330
- Website
- https://www.amtrak.com/home.html
Train from Alexandria to Miami Amtrak Station
- Ave. Duration
- 23h 14m
- Frequency
- Twice daily
- Estimated price
- $110–340
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Indianapolis to Atlanta Bus Station
- Ave. Duration
- 9h 55m
- Frequency
- Twice daily
- Estimated price
- $60–120
- Schedules at
- flixbus.com
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 13h 30m
- Frequency
- Once daily
- Estimated price
- $60–150
- Schedules at
- flixbus.com
Bus from Indianapolis to Cincinnati
- Ave. Duration
- 2h
- Frequency
- 6 times a week
- Estimated price
- $15–85
- Schedules at
- flixbus.com
- Adult
- $15–85
Bus from Atlanta Bus Station to Macon Bus Station
- Ave. Duration
- 1h 30m
- Frequency
- 3 times a day
- Estimated price
- $16–25
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 17h 20m
- Frequency
- Once daily
- Estimated price
- $65–210
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- https://www.greyhound.com/
Bus from Indianapolis Union Station to Atlanta Bus Station
- Ave. Duration
- 11h 25m
- Frequency
- 4 times a day
- Estimated price
- $55–140
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Macon Bus Station
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $16–25
- Website
- https://www.greyhound.com/
Bus from Macon Bus Station to Miami Airport Station
- Ave. Duration
- 15h 45m
- Frequency
- Once daily
- Estimated price
- $60–140
- Website
- https://www.greyhound.com/
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 404-591-2750
- info@southeasternstages.com
- Website
- southeasternstages.com
Bus from Atlanta Bus Station to Macon Bus Station
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $29–95
- Schedules at
- southeasternstages.com
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