There are 8 ways to get from Indianapolis to Duke University by plane, bus, bus (Flixbus, Greyhound), train (Amtrak), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Indianapolis to Raleigh-Durham International Airport, bus, line 700 bus, line 6 bus
best- Fly from Indianapolis (IND) to Raleigh-Durham International Airport (RDU)plane IND - RDU
- Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
- Take the bus from Regional Transit Center to Duke St at Jackson Stbus
- Take the bus from Jackson St at Duke St to Flowers Dr at Duke Gardensbus
5h 36m$169–219Drive 587.3 mi
cheapest- Drive from Indianapolis to Duke Universitycar 587.3 mi
10h 26m$108–155Bus
- Take the bus from Indianapolis to Columbusbus
- Take the bus from Columbus to Winston Salem(Trans Center)bus
- Take the bus from Winston Salem(Trans Center) to Durhambus
17h 34m$116–178Train (Amtrak)
- Take the train from Indianapolis to Charlottesvilletrain
- Take the train from Charlottesville to Greensborotrain
- Take the train from Greensboro to Durham Amtrak Stationtrain
22h 26m$458–717Fly Indianapolis to Piedmont Triad International Airport, train
- Fly from Indianapolis (IND) to Piedmont Triad International Airport (GSO)plane IND - GSO
- Take the train from Greensboro to Durham Amtrak Stationtrain
8h 22m$137–528Bus to Covington, fly to Raleigh-Durham International Airport
- Take the bus from Indianapolis to Cincinnatibus
- Fly from Covington (CVG) to Raleigh-Durham International Airport (RDU)plane CVG - RDU
7h 53m$137–738Train via Arlington (Amtrak)
- Take the train from Indianapolis to Alexandriatrain Cardinal
- Take the train from Alexandria to Durham Amtrak Stationtrain Carolinian
26h 20m$563–883Bus, train
- Take the bus from Indianapolis to Toledobus
- Take the train from Toledo to Raleigh Union Stationtrain
- Take the bus from Union Station - Bus Platform A to Chapel Dr at Duke University Rdbus Drx
26h 46m$485–813
Indianapolis to Duke University by bus and foot
Comparing Your Travel Options
The cheapest way to get from Indianapolis to Duke University is to drive which costs $100 - $160 and takes 10h 26m.
The fastest way to get from Indianapolis to Duke University is to fly and bus and line 700 bus and line 6 bus which takes 5h 36m and costs $160 - $220.
No, there is no direct bus from Indianapolis to Duke University. However, there are services departing from Indianapolis and arriving at Flowers Dr at Duke Gardens via E Main St & S 5Th St, Columbus, Winston Salem(Trans Center) and Durham Station. The journey, including transfers, takes approximately 17h 34m.
No, there is no direct train from Indianapolis to Duke University station. However, there are services departing from Indianapolis and arriving at Durham Amtrak Station via Charlottesville and Greensboro. The journey, including transfers, takes approximately 22h 26m.
The distance between Indianapolis and Duke University is 526 miles. The road distance is 590.8 miles.
The best way to get from Indianapolis to Duke University without a car is to bus which takes 17h 34m and costs $110 - $180.
It takes approximately 5h 36m to get from Indianapolis to Duke University, including transfers.
Indianapolis to Duke University bus services, operated by Flixbus USA, depart from Indianapolis station.
Indianapolis to Duke University train services, operated by Amtrak, depart from Indianapolis station.
The best way to get from Indianapolis to Duke University is to bus which takes 17h 34m and costs $110 - $180. Alternatively, you can train, which costs $450 - $750 and takes 22h 26m.
What companies run services between Indianapolis, IN, USA and Duke University, NC, USA?
You can take a bus from Indianapolis to Duke University via Columbus, E Main St & S 5Th St, S Grant Ave & E Mound St, Columbus, Winston Salem(Trans Center), Durham, Durham Station, and Flowers Dr at Duke Gardens in around 17h 34m. Alternatively, you can take a train from Indianapolis to Duke University via Charlottesville, Greensboro, Durham Amtrak Station, Durham Station, and Erwin Rd at Downing St in around 22h 26m.
- Website
- delta.com
Flights from Indianapolis to Raleigh-Durham International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $95–600
Flights from Indianapolis to Raleigh-Durham International Airport via Detroit
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $120–650
Flights from Indianapolis to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $120–700
Flights from Indianapolis to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $90–490
Flights from Indianapolis to Piedmont Triad International Airport via Detroit
- Ave. Duration
- 5h 11m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $85–480
Flights from Covington to Raleigh-Durham International Airport
- Ave. Duration
- 1h 28m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–700
- Website
- southwest.com
Flights from Indianapolis to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 3h 50m
- When
- Monday, Thursday, and Friday
- Estimated price
- $110–650
Flights from Indianapolis to Raleigh-Durham International Airport via Chicago Midway
- Ave. Duration
- 3h 55m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–700
Flights from Indianapolis to Raleigh-Durham International Airport via Baltimore
- Ave. Duration
- 4h 1m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–700
Flights from Covington to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 3h 40m
- When
- Saturday to Friday
- Estimated price
- $140–800
Flights from Covington to Raleigh-Durham International Airport via Baltimore
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- $140–800
- Website
- aa.com
Flights from Indianapolis to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 3h 55m
- When
- Tuesday
- Estimated price
- $100–600
Flights from Indianapolis to Piedmont Triad International Airport via Charlotte
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $75–440
Flights from Indianapolis to Piedmont Triad International Airport via Reagan Washington
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $90–490
Flights from Indianapolis to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $95–500
Flights from Indianapolis to Piedmont Triad International Airport via Philadelphia
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $100–550
Flights from Covington to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 3h 26m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–700
- Website
- united.com
Flights from Indianapolis to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- $90–490
Flights from Indianapolis to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $95–500
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Indianapolis to Charlottesville
- Ave. Duration
- 15h 20m
- Frequency
- 3 times a week
- Estimated price
- $330–550
- Website
- Amtrak
Train from Charlottesville to Greensboro
- Ave. Duration
- 3h 33m
- Frequency
- Once daily
- Estimated price
- $90–150
- Website
- Amtrak
Train from Greensboro to Durham Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $30–50
- Website
- Amtrak
Train from Greensboro to Durham Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $30–50
- Website
- Amtrak
Train from Indianapolis to Alexandria
- Ave. Duration
- 18h 12m
- Frequency
- 3 times a week
- Estimated price
- $390–600
- Website
- Amtrak
Train from Alexandria to Durham Amtrak Station
- Ave. Duration
- 6h 32m
- Frequency
- Once daily
- Estimated price
- $170–280
- Website
- Amtrak
Train from Toledo to Raleigh Union Station
- Ave. Duration
- 19h 52m
- Frequency
- Once daily
- Estimated price
- $460–750
- Website
- Amtrak
- Phone
- +1 919 485 7433
- customerservice@gotriangle.org
- Website
- gotriangle.org
Bus from RDU Airport at Terminal 2 to Regional Transit Center
- Ave. Duration
- 12 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- gotriangle.org
- Regular one-way fare
- $3
Bus from Regional Transit Center to Duke St at Jackson St
- Ave. Duration
- 33 min
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Website
- gotriangle.org
Bus from Union Station - Bus Platform A to Chapel Dr at Duke University Rd
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- gotriangle.org
- Phone
- +1 919-485-7433
- Website
- godurhamtransit.org
Bus from Jackson St at Duke St to Flowers Dr at Duke Gardens
- Ave. Duration
- 11 min
- Frequency
- Hourly
- Estimated price
- $1
- Schedules at
- godurhamtransit.org
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Indianapolis to Columbus
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $28–45
- Schedules at
- Flixbus USA
Bus from Indianapolis to Cincinnati
- Ave. Duration
- 2h
- Frequency
- Twice daily
- Estimated price
- $17–27
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Columbus to Winston Salem(Trans Center)
- Ave. Duration
- 9h 20m
- Frequency
- Once daily
- Estimated price
- $70–110
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Durham
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $14–22
- Website
- Greyhound
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- Barons Bus
Bus from Indianapolis to Toledo
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- $21–65
- Website
- Barons Bus
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Booking & Getting There
Indianapolis to Duke University bus services, operated by Flixbus USA, arrive at Columbus station.
Indianapolis to Duke University train services, operated by Amtrak, arrive at Charlottesville station.
Yes, the driving distance between Indianapolis to Duke University is 591 miles. It takes approximately 10h 26m to drive from Indianapolis to Duke University.
There are 350+ hotels available in Duke University.











