There are 6 ways to get from Indianapolis to Duke University by plane, bus, bus (Flixbus, Greyhound), train (Amtrak), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, bus, line 700 bus, line 6 bus
best- Fly from Indianapolis (IND) to Raleigh-Durham International Airport (RDU)plane IND - RDU
- Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
- Take the bus from Regional Transit Center to Durham Station Gate Jbus
- Take the bus from Durham Station to Flowers Dr at Duke Gardensbus
5h 41m$173–406Train, bus
cheapest- Take the train from Indianapolis to Ashland Amtrak Stationtrain
- Take the bus from Ashland Bus Station to Winston Salem(Trans Center)bus
- Take the bus from Coble Transportation Center to N Columbia St at W Franklin Stbus 4
19h 31m$84–206Bus
- Take the bus from Indianapolis to Columbusbus
- Take the bus from Columbus to Winston Salem(Trans Center)bus
- Take the bus from Winston Salem(Trans Center) to Durhambus
17h 45m$126–309Train (Amtrak)
- Take the train from Indianapolis to Charlottesvilletrain
- Take the train from Charlottesville to Greensborotrain
- Take the train from Greensboro to Durham Amtrak Stationtrain
22h 26m$120–336Drive 587.3 mi
- Drive from Indianapolis to Duke Universitycar 587.3 mi
10h 19m$108–155Train via Arlington (Amtrak)
- Take the train from Indianapolis to Alexandriatrain Cardinal
- Take the train from Alexandria to Durham Amtrak Stationtrain Carolinian
27h 20m$199–521
Indianapolis to Duke University by bus and foot
Questions & Answers
The cheapest way to get from Indianapolis to Duke University is to train and bus which costs $80 - $210 and takes 19h 31m.
The fastest way to get from Indianapolis to Duke University is to fly and bus and line 700 bus and line 6 bus which takes 5h 41m and costs $170 - $410.
No, there is no direct bus from Indianapolis to Duke University. However, there are services departing from Indianapolis and arriving at Flowers Dr at Duke Gardens via E Main St & S 5Th St, Columbus, Winston Salem(Trans Center) and Durham Station. The journey, including transfers, takes approximately 17h 45m.
The distance between Indianapolis and Duke University is 524 miles. The road distance is 590.8 miles.
The best way to get from Indianapolis to Duke University without a car is to bus which takes 17h 45m and costs $120 - $310.
It takes approximately 5h 41m to get from Indianapolis to Duke University, including transfers.
Indianapolis to Duke University bus services, operated by Flixbus USA, depart from Indianapolis station.
The best way to get from Indianapolis to Duke University is to bus which takes 17h 45m and costs $120 - $310. Alternatively, you can train, which costs $120 - $340 and takes 22h 26m.
Indianapolis to Duke University bus services, operated by Flixbus USA, arrive at Columbus station.
Yes, the driving distance between Indianapolis to Duke University is 591 miles. It takes approximately 10h 19m to drive from Indianapolis to Duke University.
What companies run services between Indianapolis, IN, USA and Duke University, NC, USA?
You can take a bus from Indianapolis to Duke University via Columbus, E Main St & S 5Th St, S Grant Ave & E Mound St, Columbus, Winston Salem(Trans Center), Durham, Durham Station, and Flowers Dr at Duke Gardens in around 17h 45m. Alternatively, you can take a train from Indianapolis to Duke University via Charlottesville, Greensboro, Durham Amtrak Station, Durham Station Gate H, and Erwin Rd at Downing St in around 22h 26m.
- Website
- delta.com
Flights from Indianapolis to Raleigh-Durham International Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $75–440
Flights from Indianapolis to Raleigh-Durham International Airport via Detroit
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $95–500
Flights from Indianapolis to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $100–550
- Website
- southwest.com
Flights from Indianapolis to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 4h 2m
- When
- Monday to Friday
- Estimated price
- $90–490
Flights from Indianapolis to Raleigh-Durham International Airport via Baltimore
- Ave. Duration
- 4h
- When
- Thursday, Friday, and Sunday
- Estimated price
- $95–550
Flights from Indianapolis to Raleigh-Durham International Airport via Chicago Midway
- Ave. Duration
- 4h 10m
- When
- Monday to Friday
- Estimated price
- $100–550
- Website
- united.com
Flights from Indianapolis to Raleigh-Durham International Airport via Washington Dulles
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $90–500
- Website
- aa.com
Flights from Indianapolis to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $80–460
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Indianapolis to Charlottesville
- Ave. Duration
- 15h 20m
- Frequency
- 3 times a week
- Estimated price
- $55–200
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $55–150
- Coach Seat short notice purchase
- $75–200
- Business - advance purchase
- $100–440
- Business Class
- $170–450
Train from Charlottesville to Greensboro
- Ave. Duration
- 3h 33m
- Frequency
- Once daily
- Estimated price
- $50–130
- Website
- https://www.amtrak.com/home.html
Train from Greensboro to Durham Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $11–13
- Website
- https://www.amtrak.com/home.html
Train from Indianapolis to Ashland Amtrak Station
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a week
- Estimated price
- $30–110
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $30–70
- Coach Seat short notice purchase
- $35–110
- Business - advance purchase
- $45–220
- Business Class
- $75–280
Train from Indianapolis to Alexandria
- Ave. Duration
- 18h 12m
- Frequency
- 3 times a week
- Estimated price
- $140–350
- Website
- https://www.amtrak.com/home.html
Train from Alexandria to Durham Amtrak Station
- Ave. Duration
- 7h 32m
- Frequency
- Once daily
- Estimated price
- $50–170
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 919 485 7433
- customerservice@gotriangle.org
- Website
- gotriangle.org
Bus from RDU Airport at Terminal 2 to Regional Transit Center
- Ave. Duration
- 15 min
- Frequency
- Hourly
- Estimated price
- $1–3
- Website
- https://gotriangle.org/
- Schedules at
- https://gotriangle.org/maps-schedules/gotriangle
- Seniors 65+, youth 12 and under
- $0
- disabled, medicare
- $1
- Regular one-way fare
- $3
Bus from Regional Transit Center to Durham Station Gate J
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Website
- https://gotriangle.org/
- Schedules at
- https://gotriangle.org/maps-schedules/gotriangle
- Phone
- +1 919-485-7433
- Website
- godurhamtransit.org
Bus from Durham Station to Flowers Dr at Duke Gardens
- Ave. Duration
- 12 min
- Frequency
- Hourly
- Estimated price
- $1
- Schedules at
- godurhamtransit.org
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Indianapolis to Columbus
- Ave. Duration
- 3h 25m
- Frequency
- Twice daily
- Estimated price
- $30–55
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Columbus to Winston Salem(Trans Center)
- Ave. Duration
- 9h 25m
- Frequency
- Once daily
- Estimated price
- $65–190
- Website
- https://www.greyhound.com/
Bus from Winston Salem(Trans Center) to Durham
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $27–60
- Website
- https://www.greyhound.com/
Bus from Ashland Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 7h 10m
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
- Phone
- +1 336-662-0002
- Website
- partnc.org
Bus from Coble Transportation Center to N Columbia St at W Franklin St
- Ave. Duration
- 1h 51m
- Frequency
- Twice daily
- Estimated price
- $3
- Schedules at
- partnc.org
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 355+ hotels available in Duke University.











