There are 10 ways to get from Manhattan to Duke University by bus, plane, bus (Flixbus), train (Amtrak), car, train, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Laguardia Airport, fly to Raleigh-Durham International Airport, bus, line 700 bus, line 6 bus
best- Take the bus from E 125 St/Lexington Av to Laguardia Rd/94 Stbus
- Fly from Laguardia Airport (LGA) to Raleigh-Durham International Airport (RDU)plane LGA - RDU
- Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
- Take the bus from Regional Transit Center to Pettigrew St at Parking Deckbus
- Take the bus from Durham Station to Flowers Dr at Duke Gardensbus
5h 24m$75–424Bus (Flixbus)
- Take the bus from New York Midtown to Durhambus FlixBus N2471 / ...
11h 1m$82–133Train (Amtrak)
- Take the train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak Stationtrain Carolinian
13h 27m$184–358Drive 489.4 mi
- Drive from Manhattan to Duke Universitycar 489.4 mi
8h 47m$90–129Train to Newark Liberty International Airport, fly to Raleigh-Durham International Airport, bus, line 700 bus, line 6 bus
- Take the train from New York Penn Station to Newark Airport Railroad Stationtrain
- Fly from Newark Liberty International Airport (EWR) to Raleigh-Durham International Airport (RDU)plane EWR - RDU
- Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
- Take the bus from Regional Transit Center to Pettigrew St at Parking Deckbus
- Take the bus from Durham Station to Flowers Dr at Duke Gardensbus
5h 22m$187–1,134Train to John F. Kennedy International Airport, fly to Raleigh-Durham International Airport, bus, line 700 bus, line 6 bus
- Take the train from Grand Central Terminal to Jamaicatrain
- Fly from John F. Kennedy International Airport (JFK) to Raleigh-Durham International Airport (RDU)plane JFK - RDU
- Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
- Take the bus from Regional Transit Center to Pettigrew St at Parking Deckbus
- Take the bus from Durham Station to Flowers Dr at Duke Gardensbus
5h 27m$241–925Fly Laguardia Airport to Piedmont Triad International Airport, train
- Fly from Laguardia Airport (LGA) to Piedmont Triad International Airport (GSO)plane LGA - GSO
- Take the train from Greensboro to Durham Amtrak Stationtrain
6h 12m$151–678Fly Newark Liberty International Airport to Piedmont Triad International Airport, train
- Fly from Newark Liberty International Airport (EWR) to Piedmont Triad International Airport (GSO)plane EWR - GSO
- Take the train from Greensboro to Durham Amtrak Stationtrain
6h 10m$148–578Train to Westchester County Airport, fly to Raleigh-Durham International Airport, bus, line 700 bus
- Take the train from 125th Street - Harlem to White Plainstrain
- Fly from Westchester County Airport (HPN) to Raleigh-Durham International Airport (RDU)plane HPN - RDU
- Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
- Take the bus from Regional Transit Center to Pettigrew St at Parking Deckbus
7h 9m$99–494Bus via Port Authority Bus Terminal (Greyhound)
- Take the bus from Port Authority Bus Terminal to Durhambus Greyhound US0670
13h 36m$85–155
Manhattan to Duke University by bus and foot (Flixbus)
Questions & Answers
The cheapest way to get from Manhattan to Duke University is to bus which costs $80 - $140 and takes 11h 1m.
The fastest way to get from Manhattan to Duke University is to train and fly and bus and line 700 bus and line 6 bus which takes 5h 22m and costs $180 - $1,200.
No, there is no direct bus from Manhattan to Duke University. However, there are services departing from New York Midtown and arriving at Flowers Dr at Duke Gardens via Durham Station. The journey, including transfers, takes approximately 11h 1m.
No, there is no direct train from Manhattan station to Duke University station. However, there are services departing from Ny Moynihan Train Hall At Penn Station and arriving at Durham Amtrak Station via . The journey, including transfers, takes approximately 13h 27m.
The distance between Manhattan and Duke University is 460 miles. The road distance is 492.3 miles.
The best way to get from Manhattan to Duke University without a car is to bus which takes 11h 1m and costs $80 - $140.
It takes approximately 5h 24m to get from Manhattan to Duke University, including transfers.
Manhattan to Duke University bus services, operated by Flixbus USA, depart from New York Midtown station.
Manhattan to Duke University train services, operated by Amtrak, depart from Ny Moynihan Train Hall At Penn Station.
The best way to get from Manhattan to Duke University is to bus which takes 11h 1m and costs $80 - $140. Alternatively, you can train, which costs $180 - $360 and takes 13h 27m.
What companies run services between Manhattan, NY, USA and Duke University, NC, USA?
Flixbus USA operates a bus from New York Midtown to Durham twice daily. Tickets cost $80–140 and the journey takes 10h 25m. Alternatively, Amtrak operates a train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak Station once daily. Tickets cost $180–360 and the journey takes 12h 51m.
- Website
- aa.com
Flights from Laguardia Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 59m
- When
- Every day
- Estimated price
- $65–410
Flights from Newark Liberty International Airport to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 4h 6m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $70–380
Flights from John F. Kennedy International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- $55–330
Flights from John F. Kennedy International Airport to Raleigh-Durham International Airport via Reagan Washington
- Ave. Duration
- 3h 44m
- When
- Monday to Friday
- Estimated price
- $55–330
Flights from John F. Kennedy International Airport to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $70–380
Flights from Laguardia Airport to Piedmont Triad International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $100–600
Flights from Laguardia Airport to Piedmont Triad International Airport via Reagan Washington
- Ave. Duration
- 3h 54m
- When
- Monday to Friday
- Estimated price
- $100–600
Flights from Laguardia Airport to Piedmont Triad International Airport via Charlotte
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $120–700
Flights from Newark Liberty International Airport to Piedmont Triad International Airport via Charlotte
- Ave. Duration
- 4h 17m
- When
- Monday to Friday
- Estimated price
- $95–550
Flights from Westchester County Airport to Raleigh-Durham International Airport via Reagan Washington
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $80–470
Flights from Westchester County Airport to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 4h 12m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
- Website
- delta.com
Flights from Laguardia Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 58m
- When
- Every day
- Estimated price
- $65–410
Flights from Newark Liberty International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $55–330
Flights from John F. Kennedy International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 2h 9m
- When
- Every day
- Estimated price
- $55–330
Flights from Laguardia Airport to Piedmont Triad International Airport
- Ave. Duration
- 2h 3m
- When
- Every day
- Estimated price
- $100–600
Flights from Laguardia Airport to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 4h 31m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $170–850
- Website
- united.com
Flights from Laguardia Airport to Raleigh-Durham International Airport via Washington Dulles
- Ave. Duration
- 3h 36m
- When
- Every day
- Estimated price
- $70–420
Flights from Newark Liberty International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $55–330
Flights from Newark Liberty International Airport to Raleigh-Durham International Airport via Washington Dulles
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $55–340
Flights from Laguardia Airport to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $100–600
Flights from Newark Liberty International Airport to Piedmont Triad International Airport
- Ave. Duration
- 1h 48m
- When
- Every day
- Estimated price
- $80–480
Flights from Newark Liberty International Airport to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 4h 10m
- When
- Tuesday, Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–490
- Website
- jetblue.com
Flights from John F. Kennedy International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- $55–330
- Website
- flybreeze.com
Flights from Westchester County Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $190–1,300
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak Station
- Ave. Duration
- 12h 51m
- Frequency
- Once daily
- Estimated price
- $180–360
- Website
- https://www.amtrak.com/home.html
Train from Greensboro to Durham Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $18–35
- Website
- https://www.amtrak.com/home.html
Train from Greensboro to Durham Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $18–35
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 973-275-5555
- Website
- njtransit.com
Train from New York Penn Station to Newark Airport Railroad Station
- Ave. Duration
- 24 min
- Frequency
- Every 20 minutes
- Estimated price
- $15–19
- Website
- https://www.njtransit.com
- Website
- https://njtworldcup.com/
- Adult Airport
- $15–19
- Phone
- +1-718-217-5477
- Website
- mta.info
Train from Grand Central Terminal to Jamaica
- Ave. Duration
- 20 min
- Frequency
- Every 20 minutes
- Estimated price
- $5–9
- Website
- https://www.mta.info/agency/long-island-rail-road
- Schedules at
- https://www.mta.info/agency/long-island-rail-road/timetables
- Off-Peak
- $5–8
- Peak
- $5–9
- Phone
- +1 877.690.5114
- Website
- mta.info
Train from 125th Street - Harlem to White Plains
- Ave. Duration
- 42 min
- Frequency
- Every 20 minutes
- Estimated price
- $8–14
- Website
- https://www.mta.info/agency/metro-north-railroad
- Schedules at
- https://www.mta.info/schedules
- Off-Peak
- $8–10
- Peak
- $12–14
- Phone
- 877-690-5116
- Website
- mta.info
Bus from E 125 St/Lexington Av to Laguardia Rd/94 St
- Ave. Duration
- 24 min
- Frequency
- Every 10 minutes
- Estimated price
- $2–7
- Website
- https://www.mta.info/
- Schedules at
- https://www.mta.info/schedules
- Website
- https://www.mta.info/world-cup-2026-new-york-new-jersey
- Standard Fare
- $2–7
- Phone
- +1 919 485 7433
- customerservice@gotriangle.org
- Website
- gotriangle.org
Bus from RDU Airport at Terminal 2 to Regional Transit Center
- Ave. Duration
- 15 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- https://gotriangle.org/
- Regular one-way fare
- $3
Bus from Regional Transit Center to Pettigrew St at Parking Deck
- Ave. Duration
- 35 min
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Website
- https://gotriangle.org/
Bus from RDU Airport at Terminal 2 to Regional Transit Center
- Ave. Duration
- 15 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- https://gotriangle.org/
- Regular one-way fare
- $3
Bus from Regional Transit Center to Pettigrew St at Parking Deck
- Ave. Duration
- 35 min
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Website
- https://gotriangle.org/
Bus from RDU Airport at Terminal 2 to Regional Transit Center
- Ave. Duration
- 15 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- https://gotriangle.org/
- Regular one-way fare
- $3
Bus from Regional Transit Center to Pettigrew St at Parking Deck
- Ave. Duration
- 35 min
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Website
- https://gotriangle.org/
Bus from RDU Airport at Terminal 2 to Regional Transit Center
- Ave. Duration
- 15 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- https://gotriangle.org/
- Regular one-way fare
- $3
Bus from Regional Transit Center to Pettigrew St at Parking Deck
- Ave. Duration
- 35 min
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Website
- https://gotriangle.org/
- Phone
- +1 919-485-7433
- Website
- godurhamtransit.org
Bus from Durham Station to Flowers Dr at Duke Gardens
- Ave. Duration
- 12 min
- Frequency
- Hourly
- Estimated price
- $1
- Schedules at
- godurhamtransit.org
Bus from Durham Station to Flowers Dr at Duke Gardens
- Ave. Duration
- 12 min
- Frequency
- Hourly
- Estimated price
- $1
- Schedules at
- godurhamtransit.org
Bus from Durham Station to Flowers Dr at Duke Gardens
- Ave. Duration
- 12 min
- Frequency
- Hourly
- Estimated price
- $1
- Schedules at
- godurhamtransit.org
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from New York Midtown to Durham
- Ave. Duration
- 10h 25m
- Frequency
- Twice daily
- Estimated price
- $80–140
- Schedules at
- flixbus.com
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Port Authority Bus Terminal to Durham
- Ave. Duration
- 13h
- Frequency
- 3 times a day
- Estimated price
- $80–160
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
How to get from JFK to New York City
Read the travel guide
More Questions & Answers
Manhattan to Duke University bus services, operated by Flixbus USA, arrive at Durham station.
Manhattan to Duke University train services, operated by Amtrak, arrive at Durham Amtrak Station.
Yes, the driving distance between Manhattan to Duke University is 492 miles. It takes approximately 8h 47m to drive from Manhattan to Duke University.
There are 391+ hotels available in Duke University.













