There are 10 ways to get from Manhattan to Duke University by bus, plane, bus (Flixbus), train (Amtrak), car, train, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Newark Liberty International Airport, fly to Raleigh-Durham International Airport
best- Take the bus from Port Authority Bus Terminal to Terminal Bbus
- Fly from Newark Liberty International Airport (EWR) to Raleigh-Durham International Airport (RDU)plane EWR - RDU
5h 22m$202–872Bus (Flixbus)
cheapest- Take the bus from New York Midtown to Durhambus FlixBus N2471 / ...
11h 1m$81–129Train (Amtrak)
- Take the train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak Stationtrain Carolinian
13h 23m$164–348Drive 489.4 mi
- Drive from Manhattan to Duke Universitycar 489.4 mi
8h 48m$90–129Bus to Laguardia Airport, fly to Raleigh-Durham International Airport, bus, line 700 bus, line 6 bus
- Take the bus from E 125 St/Lexington Av to Laguardia Rd/94 Stbus
- Fly from Laguardia Airport (LGA) to Raleigh-Durham International Airport (RDU)plane LGA - RDU
- Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
- Take the bus from Regional Transit Center to Duke St at Jackson Stbus
- Take the bus from Jackson St at Duke St to Flowers Dr at Duke Gardensbus
5h 18m$130–454Train to John F. Kennedy International Airport, fly to Raleigh-Durham International Airport, bus, line 700 bus, line 6 bus
- Take the train from Grand Central Terminal to Jamaicatrain
- Fly from John F. Kennedy International Airport (JFK) to Raleigh-Durham International Airport (RDU)plane JFK - RDU
- Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
- Take the bus from Regional Transit Center to Duke St at Jackson Stbus
- Take the bus from Jackson St at Duke St to Flowers Dr at Duke Gardensbus
5h 20m$401–1,325Fly Laguardia Airport to Piedmont Triad International Airport, train
- Fly from Laguardia Airport (LGA) to Piedmont Triad International Airport (GSO)plane LGA - GSO
- Take the train from Greensboro to Durham Amtrak Stationtrain
6h 12m$178–828Bus to Newark Liberty International Airport, fly to Piedmont Triad International Airport, train
- Take the bus from Port Authority Bus Terminal to Terminal Bbus
- Fly from Newark Liberty International Airport (EWR) to Piedmont Triad International Airport (GSO)plane EWR - GSO
- Take the train from Greensboro to Durham Amtrak Stationtrain
6h 21m$170–736Train to Westchester County Airport, fly to Raleigh-Durham International Airport, line 700 bus
- Take the train from 125th Street - Harlem to White Plainstrain
- Fly from Westchester County Airport (HPN) to Raleigh-Durham International Airport (RDU)plane HPN - RDU
- Take the bus from Regional Transit Center to Duke St at Jackson Stbus
7h 2m$118–673Bus via Port Authority Bus Terminal (Greyhound)
- Take the bus from Port Authority Bus Terminal to Durhambus Greyhound US0670
13h 36m$81–153
Manhattan to Duke University by bus and foot (Flixbus)
Comparing Your Travel Options
The cheapest way to get from Manhattan to Duke University is to bus which costs $80 - $130 and takes 11h 1m.
The fastest way to get from Manhattan to Duke University is to bus and fly and line 700 bus and line 6 bus which takes 5h 18m and costs $130 - $460.
No, there is no direct bus from Manhattan to Duke University. However, there are services departing from New York Midtown and arriving at Flowers Dr at Duke Gardens via Durham Station. The journey, including transfers, takes approximately 11h 1m.
No, there is no direct train from Manhattan station to Duke University station. However, there are services departing from Ny Moynihan Train Hall At Penn Station and arriving at Durham Amtrak Station via . The journey, including transfers, takes approximately 13h 23m.
The distance between Manhattan and Duke University is 500 miles. The road distance is 492.3 miles.
The best way to get from Manhattan to Duke University without a car is to bus which takes 11h 1m and costs $80 - $130.
It takes approximately 5h 22m to get from Manhattan to Duke University, including transfers.
Manhattan to Duke University bus services, operated by Flixbus USA, depart from New York Midtown station.
Manhattan to Duke University train services, operated by Amtrak, depart from Ny Moynihan Train Hall At Penn Station.
The best way to get from Manhattan to Duke University is to bus which takes 11h 1m and costs $80 - $130. Alternatively, you can train, which costs $160 - $350 and takes 13h 23m.
What companies run services between Manhattan, NY, USA and Duke University, NC, USA?
Flixbus USA operates a bus from New York Midtown to Durham twice daily. Tickets cost $80–130 and the journey takes 10h 25m. Alternatively, Amtrak operates a train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak Station once daily. Tickets cost $160–350 and the journey takes 12h 51m.
- Website
- delta.com
Flights from Newark Liberty International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- $65–400
Flights from Laguardia Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 57m
- When
- Every day
- Estimated price
- $80–500
Flights from Laguardia Airport to Raleigh-Durham International Airport via Reagan Washington
- Ave. Duration
- 3h 40m
- When
- Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $85–500
Flights from John F. Kennedy International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 2h 3m
- When
- Every day
- Estimated price
- $60–380
Flights from Laguardia Airport to Piedmont Triad International Airport
- Ave. Duration
- 1h 57m
- When
- Every day
- Estimated price
- $130–750
- Website
- aa.com
Flights from Newark Liberty International Airport to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 3h 49m
- When
- Every day
- Estimated price
- $85–460
Flights from Laguardia Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- $80–500
Flights from John F. Kennedy International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 58m
- When
- Every day
- Estimated price
- $60–380
Flights from Laguardia Airport to Piedmont Triad International Airport
- Ave. Duration
- 1h 54m
- When
- Every day
- Estimated price
- $130–750
Flights from Laguardia Airport to Piedmont Triad International Airport via Charlotte
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $150–850
Flights from Laguardia Airport to Piedmont Triad International Airport via Reagan Washington
- Ave. Duration
- 4h 6m
- When
- Monday to Friday
- Estimated price
- $130–800
Flights from Westchester County Airport to Raleigh-Durham International Airport via Reagan Washington
- Ave. Duration
- 3h 58m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–650
Flights from Westchester County Airport to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 4h 2m
- When
- Monday to Saturday
- Estimated price
- $130–700
- Website
- united.com
Flights from Newark Liberty International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $65–400
Flights from Newark Liberty International Airport to Raleigh-Durham International Airport via Washington Dulles
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $65–400
Flights from Laguardia Airport to Raleigh-Durham International Airport via Washington Dulles
- Ave. Duration
- 3h 32m
- When
- Every day
- Estimated price
- $85–500
Flights from Laguardia Airport to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $130–800
Flights from Newark Liberty International Airport to Piedmont Triad International Airport
- Ave. Duration
- 1h 54m
- When
- Every day
- Estimated price
- $100–600
Flights from Newark Liberty International Airport to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $100–600
- Website
- jetblue.com
Flights from John F. Kennedy International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 51m
- When
- Every day
- Estimated price
- $60–380
- Website
- flybreeze.com
Flights from Westchester County Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $230–1,500
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak Station
- Ave. Duration
- 12h 51m
- Frequency
- Once daily
- Estimated price
- $160–350
- Website
- Amtrak
Train from Greensboro to Durham Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $15–35
- Website
- Amtrak
Train from Greensboro to Durham Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $15–35
- Website
- Amtrak
- Phone
- +1-718-217-5477
- Website
- Long Island Rail Road
Train from Grand Central Terminal to Jamaica
- Ave. Duration
- 21 min
- Frequency
- Every 15 minutes
- Estimated price
- $5–9
- Website
- Long Island Rail Road
- Schedules at
- Long Island Rail Road Schedules
- Off-Peak
- $5–8
- Peak
- $5–9
- Phone
- +1 877.690.5114
- Website
- Metro North Railroad
Train from 125th Street - Harlem to White Plains
- Ave. Duration
- 41 min
- Frequency
- Every 20 minutes
- Estimated price
- $8–14
- Website
- Metro North Railroad
- Schedules at
- Metro North Railroad Schedules
- Off-Peak
- $8–10
- Peak
- $12–14
- Phone
- +1 (866) 912-6224
- olympia@coachusa.com
- Website
- newarkairportexpress.com
Bus from Port Authority Bus Terminal to Terminal B
- Ave. Duration
- 40 min
- Frequency
- Every 30 minutes
- Estimated price
- $25
- Book at
- Coach USA
- One Way - Adult
- $25
Bus from Port Authority Bus Terminal to Terminal B
- Ave. Duration
- 40 min
- Frequency
- Every 30 minutes
- Estimated price
- $25
- Book at
- Coach USA
- One Way - Adult
- $25
- Phone
- +1 610-868-6001
- webmaster@transbridgelines.com
- Website
- transbridgelines.com
Bus from Port Authority Bus Terminal to Terminal B
- Ave. Duration
- 30 min
- Frequency
- 5 times a day
- Estimated price
- $60–66
- Schedules at
- transbridgelines.com
- Adult
- $60–66
Bus from Port Authority Bus Terminal to Terminal B
- Ave. Duration
- 30 min
- Frequency
- 5 times a day
- Estimated price
- $60–66
- Schedules at
- transbridgelines.com
- Adult
- $60–66
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from New York Midtown to Durham
- Ave. Duration
- 10h 25m
- Frequency
- Twice daily
- Estimated price
- $80–130
- Schedules at
- Flixbus USA
- Phone
- 877-690-5116
- Website
- MTA
Bus from E 125 St/Lexington Av to Laguardia Rd/94 St
- Ave. Duration
- 24 min
- Frequency
- Every 10 minutes
- Estimated price
- $3–8
- Website
- MTA
- Schedules at
- MTA scheduled
- Website
- MTA: World Cup 2026
- Standard Fare
- $3–8
- Phone
- +1 919 485 7433
- customerservice@gotriangle.org
- Website
- gotriangle.org
Bus from RDU Airport at Terminal 2 to Regional Transit Center
- Ave. Duration
- 12 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- gotriangle.org
- Regular one-way fare
- $3
Bus from Regional Transit Center to Duke St at Jackson St
- Ave. Duration
- 33 min
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Website
- gotriangle.org
Bus from RDU Airport at Terminal 2 to Regional Transit Center
- Ave. Duration
- 12 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- gotriangle.org
- Regular one-way fare
- $3
Bus from Regional Transit Center to Duke St at Jackson St
- Ave. Duration
- 33 min
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Website
- gotriangle.org
Bus from Regional Transit Center to Duke St at Jackson St
- Ave. Duration
- 33 min
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Website
- gotriangle.org
- Phone
- +1 919-485-7433
- Website
- godurhamtransit.org
Bus from Jackson St at Duke St to Flowers Dr at Duke Gardens
- Ave. Duration
- 11 min
- Frequency
- Hourly
- Estimated price
- $1
- Schedules at
- godurhamtransit.org
Bus from Jackson St at Duke St to Flowers Dr at Duke Gardens
- Ave. Duration
- 11 min
- Frequency
- Hourly
- Estimated price
- $1
- Schedules at
- godurhamtransit.org
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Port Authority Bus Terminal to Durham
- Ave. Duration
- 13h
- Frequency
- 3 times a day
- Estimated price
- $80–160
- Website
- Greyhound
Want to know more about travelling around United States
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Booking & Getting There
Manhattan to Duke University bus services, operated by Flixbus USA, arrive at Durham station.
Manhattan to Duke University train services, operated by Amtrak, arrive at Durham Amtrak Station.
Yes, the driving distance between Manhattan to Duke University is 492 miles. It takes approximately 8h 48m to drive from Manhattan to Duke University.
There are 411+ hotels available in Duke University.




















