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How to get fromManhattan to Duke Universityby train, plane, bus, bus (Flixbus), train (Amtrak), car or bus (Greyhound)

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There are 9 ways to get from Manhattan to Duke University by train, plane, bus, bus (Flixbus), train (Amtrak), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Newark Liberty International Airport, fly to Raleigh-Durham International Airport, bus, line 700 bus, line 6 bus

    best
    1. Take the train from New York Penn Station to Newark Airport Railroad Stationtrain
    2. Fly from Newark Liberty International Airport (EWR) to Raleigh-Durham International Airport (RDU)planeEWR - RDU
    3. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
    4. Take the bus from Regional Transit Center to Durham Station Gate Jbus
    5. Take the bus from Durham Station to Flowers Dr at Duke Gardensbus
    5h 20m
    $66–411
  2. Bus (Flixbus)

    1. Take the bus from New York Midtown to DurhambusFlixBus N2471 / ...
    11h 6m
    $82–187
  3. Train (Amtrak)

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak StationtrainCarolinian
    12h 26m
    $121–343
  4. Drive 489.1 mi

    1. Drive from Manhattan to Duke Universitycar489.1 mi
    8h 43m
    $90–129
  5. Bus to Laguardia Airport, fly to Raleigh-Durham International Airport, bus, line 700 bus, line 6 bus

    1. Take the bus from E 125 St/Lexington Av to Laguardia Rd/94 Stbus
    2. Fly from Laguardia Airport (LGA) to Raleigh-Durham International Airport (RDU)planeLGA - RDU
    3. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
    4. Take the bus from Regional Transit Center to Durham Station Gate Jbus
    5. Take the bus from Durham Station to Flowers Dr at Duke Gardensbus
    5h 31m
    $104–411
  6. Train to John F. Kennedy International Airport, fly to Raleigh-Durham International Airport, bus, line 700 bus, line 6 bus

    1. Take the train from Grand Central Terminal to Jamaicatrain
    2. Fly from John F. Kennedy International Airport (JFK) to Raleigh-Durham International Airport (RDU)planeJFK - RDU
    3. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
    4. Take the bus from Regional Transit Center to Durham Station Gate Jbus
    5. Take the bus from Durham Station to Flowers Dr at Duke Gardensbus
    5h 32m
    $70–342
  7. Train to Westchester County Airport, fly to Raleigh-Durham International Airport, bus, line 700 bus

    1. Take the train from 125th Street - Harlem to White Plainstrain
    2. Fly from Westchester County Airport (HPN) to Raleigh-Durham International Airport (RDU)planeHPN - RDU
    3. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
    4. Take the bus from Regional Transit Center to Durham Station Gate Jbus
    7h 18m
    $88–471
  8. Fly Laguardia Airport to Piedmont Triad International Airport, train

    1. Fly from Laguardia Airport (LGA) to Piedmont Triad International Airport (GSO)planeLGA - GSO
    2. Take the train from Greensboro to Durham Amtrak Stationtrain
    7h 51m
    $104–497
  9. Bus via Port Authority Bus Terminal (Greyhound)

    1. Take the bus from Port Authority Bus Terminal to DurhambusGreyhound US0670
    13h 36m
    $75–185

Manhattan to Duke University by bus and foot (Flixbus)

Calendar17Weekly Services
Duration11h 6mAverage Duration
Ticket$82Cheapest Price
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Questions & Answers

What companies run services between Manhattan, NY, USA and Duke University, NC, USA?

Flixbus USA operates a bus from New York Midtown to Durham twice daily. Tickets cost $80–190 and the journey takes 10h 30m. Alternatively, Amtrak operates a train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak Station once daily. Tickets cost $120–350 and the journey takes 11h 54m.

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