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How to get fromPhiladelphia to Iowaby plane, bus (Greyhound), train, bus, car, or bus (Flixbus, Greyhound)

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There are 9 ways to get from Philadelphia to Iowa by plane, bus (Greyhound), train, bus, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Philadelphia International Airport to Des Moines

    best
    1. Fly from Philadelphia International Airport (PHL) to Des Moines (DSM)plane plane PHL - DSM
    4h 21m
    $260–1,224

  2. Fly Philadelphia International Airport to Quad City International Airport

    cheapest
    1. Fly from Philadelphia International Airport (PHL) to Quad City International Airport (MLI)plane plane PHL - MLI
    7h 57m
    $125–605

  3. Bus (Greyhound)

    1. Take the bus from Philadelphia Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus Greyhound US0157S
    25h 50m
    $173–345

  4. Train, bus via Galesburg

    1. Take the train from 30th Street Station to Washington Union Stationtrain train
    2. Take the train from Rockville Amtrak to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    30h 42m
    $336–1,270

  5. Drive 1,073.9 mi

    1. Drive from Philadelphia to Des Moinescar car 1,073.9 mi
    17h 41m
    $196–284

  6. Fly Philadelphia International Airport to Omaha

    1. Fly from Philadelphia International Airport (PHL) to Omaha (OMA)plane plane PHL - OMA
    4h 47m
    $278–1,233

  7. Train to Laguardia Airport, fly to Des Moines

    1. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Laguardia Airport (LGA) to Des Moines (DSM)plane plane LGA - DSM
    6h 52m
    $265–1,733

  8. Bus via Chicago

    1. Take the bus from Philadelphia Bus Station to Chicago Bus Stationbus bus FlixBus N2642
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    27h 35m
    $177–308

  9. Train, bus

    1. Take the train from 30th Street Station to Chicago Union Stationtrain train Cardinal
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    34h 54m
    $365–752

Philadelphia International Airport (PHL) to Des Moines (DSM) flights

Calendar79Weekly Planes
Duration4h 49mAverage Duration
Ticket$247Cheapest Price
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Questions & Answers

Map of how to get from Philadelphia to Iowa.ExpandLaunch map view
  • Distance: 984 mi
  • Duration: 4h 21m

What companies run services between Philadelphia, PA, USA and Iowa, USA?

American Airlines, Allegiant Air, and three other airlines fly from Philadelphia International Airport (PHL) to Des Moines (DSM) every 2 hours. Alternatively, you can take a bus from Philadelphia Bus Station to Des Moines via Indianapolis Union Station and Des Moines in around 25h 50m.

Airlines
Train operators
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