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How to get fromHyannis to Hopkintonby bus, train, car, or bus (Greyhound)

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There are 5 ways to get from Hyannis to Hopkinton by bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train via Framingham MBTA Station

    best
    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus Hyannis - South Shore to Logan Airport
    2. Take the train from South Station to Framinghamtrain train Framingham/Worcester Line
    4h 34m
    $33–47

  2. Train

    cheapest
    1. Take the train from Hyannis to South Stationtrain train CapeFLYER
    2. Take the train from South Station to Southboroughtrain train Framingham/Worcester Line
    5h 30m
    $12–35

  3. Drive 84.5 mi

    1. Drive from Hyannis to Hopkintoncar car 84.5 mi
    1h 42m
    $16–23

  4. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus bus Hyannis
    2. Take the train from South Station to Southboroughtrain train Framingham/Worcester Line
    4h 40m
    $22–51

  5. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus Hyannis - South Shore to Logan Airport
    2. Take the bus from Boston to Framinghambus bus Greyhound US0270s
    4h 57m
    $32–44

Hyannis to Hopkinton by bus and train

Calendar69Weekly Services
Duration4h 34mAverage Duration
Ticket$33Cheapest Price
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Questions & Answers

Map of how to get from Hyannis to Hopkinton.ExpandLaunch map view
  • Distance: 101.3 mi
  • Duration: 4h 34m

What companies run services between Hyannis, MA, USA and Hopkinton, MA, USA?

You can take a train from Hyannis to Hopkinton Center via South Station, Southborough, and Southborough MBTA Station in around 5h 30m. Alternatively, you can take a bus from Hyannis Transportation Center to Hopkinton Center via Boston, Bus Terminal South Station, Boston, Framingham, and Framingham MBTA Station in around 4h 57m.

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