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How to get fromHyannis to Rochesterby bus, plane, bus (Greyhound), train, car, or bus (Flixbus)

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There are 8 ways to get from Hyannis to Rochester by bus, plane, bus (Greyhound), train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Boston Logan Airport, fly to Rochester

    best
    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    4h 24m
    $125–652

  2. Bus

    cheapest
    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus Hyannis - South Shore to Logan Airport
    2. Take the bus from Boston to Rochester Bus Stopbus bus Greyhound US0171
    11h 30m
    $82–145

  3. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus Hyannis - South Shore to Logan Airport
    2. Take the train from Boston to Rochestertrain train Lake Shore Limited
    13h 23m
    $147–295

  4. Drive 450.7 mi

    1. Drive from Hyannis to Rochestercar car 450.7 mi
    8h
    $83–119

  5. Fly Barnstable Municipal Airport to Buffalo Niagara International Airport, bus

    1. Fly from Barnstable Municipal Airport (HYA) to Buffalo Niagara International Airport (BUF)plane plane HYA - BUF
    2. Take the bus from Buffalo Niagara International Airport to Rochester Bus Stopbus bus
    5h 49m
    $101–548

  6. Fly Barnstable Municipal Airport to Rochester

    1. Fly from Barnstable Municipal Airport (HYA) to Rochester (ROC)plane plane HYA - ROC
    3h 42m
    $125–677

  7. Bus to Boston Logan Airport, fly to Buffalo Niagara International Airport, bus

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    3. Take the bus from Buffalo Niagara International Airport to Rochester Bus Stopbus bus
    6h 26m
    $104–538

  8. Bus via Ithaca

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Ithacabus bus
    3. Take the bus from Ithaca to Rochester Bus Stopbus bus
    13h 44m
    $89–146

Hyannis to Rochester by bus

Calendar7Weekly Buses
Duration11h 30mAverage Duration
Ticket$82Cheapest Price
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Questions & Answers

Map of how to get from Hyannis to Rochester.ExpandLaunch map view
  • Distance: 420.2 mi
  • Duration: 4h 24m

What companies run services between Hyannis, MA, USA and Rochester, NY, USA?

You can take a bus from Hyannis Transportation Center to Rochester Bus Stop via Boston, South Station and Boston in around 11h 30m. Alternatively, Cape Air and American Airlines fly from Barnstable Municipal Airport (HYA) to Rochester (ROC) 3 times a day.

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