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How to get fromGainesville to Key Westby plane, bus, ferry, car, shuttle, or bus (Flixbus, Greyhound)

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There are 9 ways to get from Gainesville to Key West by plane, bus, ferry, car, shuttle, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Gainesville Regional Airport

    best
    1. Fly from Gainesville Regional Airport (GNV) to Key West International Airport (EYW)plane plane GNV - EYW
    5h 36m
    $52–264

  2. Bus, ferry

    1. Take the bus from Gainesville - Commuter Lot Parking Garage @ Gale Lemerand to Naples, FLbus bus Tallahassee-Miami
    2. Take the ferry from Marco Island, FL to Key West, FLferry ferry Key West
    11h 23m
    $248–314

  3. Drive 474.4 mi

    1. Drive from Gainesville to Key Westcar car 474.4 mi
    9h 22m
    $87–126

  4. Bus to Orlando, fly

    1. Take the bus from Gainesville - Commuter Lot Parking Garage @ Gale Lemerand to Orlando - RedCoach Station, FLbus bus
    2. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    5h
    $102–667

  5. Drive to Orlando Sanford, fly

    1. Drive from Gainesville to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    3h 45m
    $66–272

  6. Bus to Jacksonville, fly

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Key West International Airport (EYW)plane plane JAX - EYW
    7h 19m
    $381–931

  7. Bus, shuttle

    1. Take the bus from Gainesville - Commuter Lot Parking Garage @ Gale Lemerand to Miami Airportbus bus Tallahassee-Miami
    2. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus To the Keys
    13h 6m
    $259–359

  8. Bus, ferry via University

    1. Take the bus from Gainesville - Commuter Lot Parking Garage @ Gale Lemerand to University of South Florida Tampabus bus
    2. Take the bus from University of South Florida to Fort Myers Bus Stopbus bus
    3. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry
    14h 50m
    $181–223

  9. Bus

    1. Take the bus from Gainesville to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus
    3. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    15h 11m
    $68–118

Gainesville to Key West by bus and shuttle

Calendar21Weekly Services
Duration13h 6mAverage Duration
Ticket$259Cheapest Price
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Questions & Answers

Map of how to get from Gainesville to Key West.ExpandLaunch map view
  • Distance: 363 mi
  • Duration: 5h 36m

What companies run services between Gainesville, FL, USA and Key West, FL, USA?

Delta and American Airlines fly from Gainesville Regional Airport (GNV) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Gainesville to N Roosevelt & 3rd Street via Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 15h 11m.

Airlines
Bus operators
Ferry operators

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