Rome2Rio

How to get fromGainesville to Buffaloby plane, bus (Flixbus, Greyhound), bus, train or car

Find Transport to Buffalo

See all options

There are 7 ways to get from Gainesville to Buffalo by plane, bus (Flixbus, Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Gainesville Regional Airport

    best
    1. Fly from Gainesville Regional Airport (GNV) to Buffalo Niagara International Airport (BUF)plane plane GNV - BUF
    6h 47m
    $206–1,182

  2. Bus

    cheapest
    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    29h 45m
    $148–293

  3. Bus, train via New York

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Take the train from Jacksonville to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train
    31h 13m
    $222–544

  4. Drive 1,097.3 mi

    1. Drive from Gainesville to Buffalocar car 1,097.3 mi
    18h 45m
    $201–290

  5. Bus to Orlando, fly

    1. Take the bus from Gainesville to Orlando RedCoach Stationbus bus
    2. Fly from Orlando (MCO) to Buffalo Niagara International Airport (BUF)plane plane MCO - BUF
    7h 25m
    $199–1,115

  6. Bus to Jacksonville, fly

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Buffalo Niagara International Airport (BUF)plane plane JAX - BUF
    9h 8m
    $291–1,604

  7. Bus, train

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Take the train from Jacksonville to Pittsburgh Amtrak Stationtrain train
    3. Take the bus from Pittsburgh to Buffalobus bus
    37h 30m
    $187–514

Gainesville to Buffalo by bus

Calendar7Weekly Buses
Duration29h 45mAverage Duration
Ticket$148Cheapest Price
See schedules

Questions & Answers

What companies run services between Gainesville, FL, USA and Buffalo, NY, USA?

Delta and American Airlines fly from Gainesville Regional Airport (GNV) to Buffalo Niagara International Airport (BUF) 5 times a day. Alternatively, you can take a bus from Gainesville to Buffalo, NY via Atlanta Bus Station, Cleveland Bus Station, and Cleveland, OH in around 29h 45m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Where to next?

Trips from Gainesville

Trips to Buffalo

Popular routes