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How to get fromSyosset to Buffaloby train, plane, bus, car, subway or train (Amtrak)

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There are 9 ways to get from Syosset to Buffalo by train, plane, bus, car, subway, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the train from Syosset to Jamaicatrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane plane JFK - BUF
    4h 9m
    $118–725

  2. Train, bus

    cheapest
    1. Take the train from Syosset to New York Penn Stationtrain train Port Jefferson Branch
    2. Take the bus from New York Midtown to Buffalobus bus FlixBus 2686 / ...
    10h 24m
    $64–120

  3. Train

    1. Take the train from Syosset to New York Penn Stationtrain train Port Jefferson Branch
    2. Take the train from New York Penn Station to Buffalotrain train VIA Rail
    10h 24m
    $69–140

  4. Drive 386.7 mi

    1. Drive from Syosset to Buffalocar car 386.7 mi
    7h 48m
    $71–102

  5. Train, subway to Laguardia Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Syosset to Jamaicatrain train
    2. Take the subway from Sutphin Blvd-Archer Av-JFK Airport to Jackson Hts-Roosevelt Avsubway subway
    3. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane plane LGA - BUF
    4h 36m
    $132–869

  6. Train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Syosset to New York Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    5h 3m
    $131–800

  7. Fly John F. Kennedy International Airport to Rochester, bus

    1. Fly from John F. Kennedy International Airport (JFK) to Rochester (ROC)plane plane JFK - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    5h 43m
    $93–439

  8. Fly Laguardia Airport to Rochester, bus

    1. Fly from Laguardia Airport (LGA) to Rochester (ROC)plane plane LGA - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    6h
    $297–713

  9. Train via New York

    1. Take the train from Syosset to New York Penn Stationtrain train Port Jefferson Branch
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train Empire Service / ...
    10h 44m
    $119–280

Syosset to Buffalo by train and bus

Calendar68Weekly Services
Duration10h 24mAverage Duration
Ticket$64Cheapest Price
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Questions & Answers

What companies run services between Syosset, NY, USA and Buffalo, NY, USA?

You can take a train from Syosset to Buffalo via New York Penn Station in around 10h 24m.

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