Rome2Rio

How to get fromSyosset to Buffaloby train, plane, bus, car, or train (Amtrak)

Find Transport to Buffalo

See all options

There are 9 ways to get from Syosset to Buffalo by train, plane, bus, car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the train from Syosset to Jamaicatrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane plane JFK - BUF
    4h 27m
    $86–511

  2. Drive  386.7 mi

    cheapest
    1. Drive from Syosset to Buffalocar car 386.7 mi
    7h 47m
    $71–102

  3. Train

    1. Take the train from Syosset to New York Penn Stationtrain train Port Jefferson Branch
    2. Take the train from New York Penn Station to Buffalotrain train VIA Rail
    10h 21m
    $120–310

  4. Train, bus

    1. Take the train from Syosset to New York Penn Stationtrain train Port Jefferson Branch
    2. Take the bus from New York Midtown to Buffalobus bus FlixBus 2686 / ...
    10h 32m
    $80–130

  5. Train to Laguardia Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Syosset to Jamaicatrain train
    2. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane plane LGA - BUF
    4h 53m
    $115–795

  6. Train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Syosset to New York Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    5h 21m
    $117–627

  7. Fly John F. Kennedy International Airport to Rochester, bus

    1. Fly from John F. Kennedy International Airport (JFK) to Rochester (ROC)plane plane JFK - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    5h 56m
    $130–665

  8. Fly Laguardia Airport to Rochester, bus

    1. Fly from Laguardia Airport (LGA) to Rochester (ROC)plane plane LGA - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    6h 14m
    $169–1,009

  9. Train via New York

    1. Take the train from Syosset to New York Penn Stationtrain train Port Jefferson Branch
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train Empire Service / ...
    10h 32m
    $250–390

Syosset to Buffalo by train

Calendar7Weekly Trains
Duration10h 21mAverage Duration
Ticket$120Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Syosset to Buffalo.ExpandLaunch map view
  • Distance: 334.7 mi
  • Duration: 4h 27m

What companies run services between Syosset, NY, USA and Buffalo, NY, USA?

You can take a train from Syosset to Buffalo via New York Penn Station in around 10h 21m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound