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How to get fromFrederick to Key Westby train, plane, bus (Greyhound, Flixbus), bus or car

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There are 9 ways to get from Frederick to Key West by train, plane, bus (Greyhound, Flixbus), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Ronald Reagan Washington National Airport, fly

    best
    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Key West International Airport (EYW)planeDCA - EYW
    6h 2m
    $207–983

  2. Bus to Washington Dulles International Airport, fly

    cheapest
    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus
    2. Fly from Washington Dulles International Airport (IAD) to Key West International Airport (EYW)planeIAD - EYW
    6h 33m
    $115–589

  3. Bus

    1. Take the bus from Frederick Bus Station to Washington Union Stationbus
    2. Take the bus from Washington Union Station to Orlando Bus Stationbus
    3. Take the bus from Orlando Bus Station to Miami Airport Stationbus
    4. Take the bus from Miami Airport Station to Big Pine Keybus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetbusLks
    31h 3m
    $154–414

  4. Train, bus

    1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain
    2. Take the train from Washington Union Station to Hollywood Amtrak Stationtrain
    3. Take the bus from Miami Airport Station to Big Pine Keybus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetbusLks
    33h 36m
    $124–1,162

  5. Drive 1,247.1 mi

    1. Drive from Frederick to Key Westcar1,247.1 mi
    21h 15m
    $228–329

  6. Bus to Baltimore-Washington International Airport, fly

    1. Take the bus from Frederick Bayrunner Office to Baltimore Airportbus
    2. Fly from Baltimore-Washington International Airport (BWI) to Key West International Airport (EYW)planeBWI - EYW
    6h 30m
    $180–440

  7. Bus to Hagerstown Regional Airport, fly

    1. Take the bus from Frederick Transit Center to Washington County Transfer Centerbus
    2. Fly from Hagerstown Regional Airport (HGR) to Key West International Airport (EYW)planeHGR - EYW
    8h 2m

  8. Bus, train to Philadelphia International Airport, fly

    1. Take the bus from Frederick Transit Center to BWI Amtrak Stationbus
    2. Take the train from BWI Thurgood Marshall to 30th Street Stationtrain
    3. Fly from Philadelphia International Airport (PHL) to Key West International Airport (EYW)planePHL - EYW
    7h 56m
    $173–2,050

  9. Train, bus via Rockville

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
    2. Take the train from Rockville Amtrak to Hollywood Amtrak Stationtrain
    3. Take the bus from Miami Airport Station to Big Pine Keybus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetbusLks
    39h 27m
    $139–420

Frederick to Key West by bus and foot

Calendar5Weekly Services
Duration31h 3mAverage Duration
Ticket$154Cheapest Price
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Questions & Answers

What companies run services between Frederick, MD, USA and Key West, FL, USA?

You can take a bus from Frederick Bus Station to N Roosevelt & 3rd Street via Washington Union Station, Orlando Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 31h 3m.

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