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How to get fromFrederick to Key Westby train, plane, bus (Greyhound, Flixbus), bus or car

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There are 7 ways to get from Frederick to Key West by train, plane, bus (Greyhound, Flixbus), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Ronald Reagan Washington National Airport, fly

    best
    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Key West International Airport (EYW)plane plane DCA - EYW
    6h 2m
    $227–1,133

  2. Bus to Washington Dulles International Airport, fly

    cheapest
    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Key West International Airport (EYW)plane plane IAD - EYW
    6h 32m
    $125–639

  3. Bus

    1. Take the bus from Frederick Bus Station to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Orlando Bus Stationbus bus
    3. Take the bus from Orlando Bus Station to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    31h 4m
    $153–400

  4. Train, bus

    1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain train
    2. Take the train from Washington Union Station to Hollywood Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    33h 36m
    $139–392

  5. Drive 1,246.2 mi

    1. Drive from Frederick to Key Westcar car 1,246.2 mi
    21h 30m
    $228–329

  6. Bus to Baltimore-Washington International Airport, fly

    1. Take the bus from Frederick Bayrunner Office to Baltimore Airportbus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Key West International Airport (EYW)plane plane BWI - EYW
    6h 49m
    $180–490

  7. Train, bus via Rockville

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the train from Rockville Amtrak to Hollywood Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    39h 27m
    $139–420

Frederick to Key West by bus and foot

Calendar5Weekly Services
Duration31h 4mAverage Duration
Ticket$153Cheapest Price
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Questions & Answers

What companies run services between Frederick, MD, USA and Key West, FL, USA?

You can take a bus from Frederick Bus Station to N Roosevelt & 3rd Street via Washington Union Station, Orlando Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 31h 4m.

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