There are 6 ways to get from Frederick to Indianapolis by bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Baltimore-Washington International Airport, fly
best- Take the bus from Frederick to Baltimorebus
- Fly from Baltimore-Washington International Airport (BWI) to Indianapolis (IND)plane BWI - IND
5h 16m$479–1,206Bus
cheapest- Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus Greyhound US0164 / ...
- Take the bus from Pittsburgh Intermodal Station to Indianapolisbus FlixBus N2642 / ...
12h 30m$79–126Train
- Take the train from FREDERICK MARC eb to Washington Union Stationtrain Marc
- Take the train from Washington Union Station to Indianapolistrain Cardinal
20h 56m$182–432Drive 518.1 mi
- Drive from Frederick to Indianapoliscar 518.1 mi
9h 13m$95–137Train to Ronald Reagan Washington National Airport, fly
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Indianapolis (IND)plane DCA - IND
5h 44m$959–1,619Bus to Washington Dulles International Airport, fly
- Take the bus from Frederick Transit Station to Market St & Harrison Stbus
- Fly from Washington Dulles International Airport (IAD) to Indianapolis (IND)plane IAD - IND
5h 55m$466–1,127
Frederick to Indianapolis by bus
Comparing Your Travel Options
The cheapest way to get from Frederick to Indianapolis is to bus which costs $75 - $130 and takes 12h 30m.
The fastest way to get from Frederick to Indianapolis is to bus and fly which takes 5h 16m and costs $470 - $1,300.
No, there is no direct bus from Frederick station to Indianapolis. However, there are services departing from Frederick Bus Station and arriving at Indianapolis via Pittsburgh Intermodal Station. The journey, including transfers, takes approximately 12h 30m.
No, there is no direct train from Frederick to Indianapolis. However, there are services departing from FREDERICK MARC eb and arriving at Indianapolis via Washington Union Station. The journey, including transfers, takes approximately 20h 56m.
The distance between Frederick and Indianapolis is 593 miles. The road distance is 521.2 miles.
The best way to get from Frederick to Indianapolis without a car is to bus which takes 12h 30m and costs $75 - $130.
It takes approximately 5h 16m to get from Frederick to Indianapolis, including transfers.
Frederick to Indianapolis bus services, operated by Greyhound USA, depart from Frederick Bus Station.
Frederick to Indianapolis train services, operated by Maryland Transit, depart from FREDERICK MARC eb station.
The best way to get from Frederick to Indianapolis is to bus which takes 12h 30m and costs $75 - $130. Alternatively, you can train, which costs $180 - $440 and takes 20h 56m.
What companies run services between Frederick, MD, USA and Indianapolis, IN, USA?
You can take a bus from Frederick Bus Station to Indianapolis via Pittsburgh Intermodal Station in around 12h 30m. Alternatively, you can take a train from FREDERICK MARC eb to Indianapolis via Washington Union Station in around 20h 56m.
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Indianapolis
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $100–600
Flights from Baltimore-Washington International Airport to Indianapolis via Nashville
- Ave. Duration
- 4h 10m
- When
- Tuesday and Wednesday
- Estimated price
- $130–700
Flights from Ronald Reagan Washington National Airport to Indianapolis via Chicago Midway
- Ave. Duration
- 4h 5m
- When
- Tuesday and Wednesday
- Estimated price
- $170–950
Flights from Ronald Reagan Washington National Airport to Indianapolis via Nashville
- Ave. Duration
- 4h 10m
- When
- Tuesday and Wednesday
- Estimated price
- $180–950
- Phone
- 1-866-743-3682
- Website
- Maryland Transit
Train from FREDERICK MARC eb to Washington Union Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $2–12
- Website
- Maryland Transit
- Standard Fare
- $2–12
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
- Phone
- +1 410-912-6000
- reservations@bayrunnershuttle.com
- Website
- BayRunner Shuttle
Bus from Frederick to Baltimore
- Ave. Duration
- 1h 25m
- Frequency
- 3 times a day
- Estimated price
- $75–110
- Schedules at
- BayRunner Shuttle
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Booking & Getting There
Frederick to Indianapolis bus services, operated by Greyhound USA, arrive at Pittsburgh Intermodal Station.
Frederick to Indianapolis train services, operated by Maryland Transit, arrive at Washington Union Station.
Yes, the driving distance between Frederick to Indianapolis is 521 miles. It takes approximately 9h 13m to drive from Frederick to Indianapolis.
Book your Frederick to Indianapolis bus tickets online with Omio and FlixBus.
There are 874+ hotels available in Indianapolis.