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How to get fromFrederick to Indianapolisby bus, plane, bus (Greyhound, Flixbus), train, car, or bus (Greyhound)

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There are 7 ways to get from Frederick to Indianapolis by bus, plane, bus (Greyhound, Flixbus), train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Baltimore-Washington International Airport, fly

    best
    1. Take the bus from Frederick Bayrunner Office to Baltimore Airportbus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Indianapolis (IND)plane plane BWI - IND
    4h 51m
    $471–1,188

  2. Bus

    cheapest
    1. Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus bus Greyhound US0164 / ...
    2. Take the bus from Pittsburgh Intermodal Station to Indianapolisbus bus FlixBus N2642 / ...
    12h 30m
    $83–148

  3. Bus, train

    1. Take the bus from Frederick Bus Station to Washington Union Stationbus bus Greyhound US0164 / ...
    2. Take the train from Washington Union Station to Indianapolistrain train Cardinal
    20h 26m
    $227–493

  4. Drive 518.1 mi

    1. Drive from Frederick to Indianapoliscar car 518.1 mi
    9h 13m
    $95–137

  5. Train to Ronald Reagan Washington National Airport, fly

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Indianapolis (IND)plane plane DCA - IND
    5h 50m
    $959–1,619

  6. Bus to Washington Dulles International Airport, fly

    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Indianapolis (IND)plane plane IAD - IND
    5h 52m
    $91–517

  7. Bus via Indianapolis Union Station (Greyhound)

    1. Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus bus Greyhound US0164 / ...
    2. Take the bus from Pittsburgh Intermodal Station to Indianapolis Union Stationbus bus Greyhound US0421
    13h
    $83–163

Frederick to Indianapolis by bus

Calendar18Weekly Buses
Duration12h 30mAverage Duration
Ticket$83Cheapest Price
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Questions & Answers

Map of how to get from Frederick to Indianapolis.ExpandLaunch map view
  • Distance: 577.9 mi
  • Duration: 4h 51m

What companies run services between Frederick, MD, USA and Indianapolis, IN, USA?

You can take a bus from Frederick Bus Station to Indianapolis via Pittsburgh Intermodal Station in around 12h 30m.

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Train operators
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