There are 9 ways to get from Florida Keys to Fort Pierce by bus (Greyhound), car, plane, bus, train, shuttle, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Big Pine Key to Miami Airport Stationbus Greyhound US0720s
- Take the bus from Miami Airport to Fort Piercebus Miami-Tallahassee / ...
8h 52m$60–214Bus via SW Gatlin Blvd & SW Brescia St
cheapest- Take the bus from Big Pine Key to Miami Airport Stationbus Greyhound US0720s
- Take the bus from Miami Airport Station to Port St Luciebus FlixBus N2411
12h 44m$42–144Drive 269.4 mi
- Drive from Florida Keys to Fort Piercecar 269.4 mi
5h 14m$50–71Fly Key West International Airport to Miami International Airport, bus
- Fly from Key West International Airport (EYW) to Miami International Airport (MIA)plane EYW - MIA
- Take the bus from Miami Airport to Fort Piercebus
7h 7m$252–844Bus, train
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the train from Miami Airport Station to West Palm Beach Stationtrain
- Take the bus from West Palm Beach, FL to Fort Piercebus
9h 20m$63–225Shuttle, bus
- Take a shuttle bus from Summerland Key - Mote Marine Lab to Miami, FL - International AirportTo the Airports
- Take the bus from Miami Airport Station to Port St Luciebus FlixBus N2411
12h 23m$149–269Fly Key West International Airport to Orlando, shuttle
- Fly from Key West International Airport (EYW) to Orlando (MCO)plane EYW - MCO
- Take a shuttle bus from Orlando Airport to Fort Pierce, FL - Dunkin' Donuts
7h 1m$249–509Fly Key West International Airport to Fort Lauderdale–Hollywood International Airport, bus
- Fly from Key West International Airport (EYW) to Fort Lauderdale–Hollywood International Airport (FLL)plane EYW - FLL
- Take the bus from Fort Lauderdale Airport to Fort Piercebus
6h 32m$156–624Shuttle to Fort Lauderdale–Hollywood International Airport, fly to Orlando, shuttle
- Take a shuttle bus from Big Pine Key, FL to Fort Lauderdale, FL - International Airport
- Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Orlando (MCO)plane FLL - MCO
- Take a shuttle bus from Orlando Airport to Fort Pierce, FL - Dunkin' Donuts
10h 12m$269–414
Florida Keys to Fort Pierce by foot, bus, shuttle, and tram
Questions & Answers
The cheapest way to get from Florida Keys to Fort Pierce is to drive which costs $45 - $75 and takes 5h 14m.
The fastest way to get from Florida Keys to Fort Pierce is to drive which takes 5h 14m and costs $45 - $75.
No, there is no direct bus from Florida Keys to Fort Pierce. However, there are services departing from Sugarloaf Key - Lower - Opposite Sugarloaf Lodge and arriving at Avenue D & N 8th St via Big Pine Key, Miami Airport Station, SW Gatlin Blvd & SW Brescia St and SE Deacon Ave & SE Belvedere St. The journey, including transfers, takes approximately 12h 44m.
The distance between Florida Keys and Fort Pierce is 281 miles. The road distance is 271 miles.
The best way to get from Florida Keys to Fort Pierce without a car is to bus which takes 8h 52m and costs $60 - $220.
It takes approximately 8h 52m to get from Florida Keys to Fort Pierce, including transfers.
Florida Keys to Fort Pierce bus services, operated by Greyhound USA, depart from Big Pine Key station.
Florida Keys to Fort Pierce bus services, operated by Greyhound USA, arrive at Miami Airport Station.
Yes, the driving distance between Florida Keys to Fort Pierce is 271 miles. It takes approximately 5h 14m to drive from Florida Keys to Fort Pierce.
There are 417+ hotels available in Fort Pierce.
What companies run services between Florida Keys, FL, USA and Fort Pierce, FL, USA?
You can take a vehicle from Florida Keys to Fort Pierce via Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami, Airport Intermodal Station, Miami Airport Station, Miami International Airport, Miami Airport, and Fort Pierce in around 8h 52m.
- Website
- aa.com
Flights from Key West International Airport to Miami International Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- $40–300
Flights from Key West International Airport to Orlando via Miami International Airport
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- $50–310
- Website
- spirit.com
Flights from Key West International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 2m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $50–210
Flights from Fort Lauderdale–Hollywood International Airport to Orlando
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- $35–110
- Website
- flybreeze.com
Flights from Key West International Airport to Orlando
- Ave. Duration
- 1h 20m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
- Website
- southwest.com
Flights from Fort Lauderdale–Hollywood International Airport to Orlando
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- $25–180
- Phone
- +1 800-874-7245
- Website
- tri-rail.com
Train from Miami Airport Station to West Palm Beach Station
- Ave. Duration
- 1h 45m
- Frequency
- Hourly
- Estimated price
- $5–11
- Website
- https://www.tri-rail.com
- Weekend | Holiday
- $5
- Weekday
- $8–11
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Big Pine Key to Miami Airport Station
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $23–55
- Website
- https://www.greyhound.com/
Bus from West Palm Beach, FL to Fort Pierce
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $25–55
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Port St Lucie
- Ave. Duration
- 3h 35m
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Miami Airport to Fort Pierce
- Ave. Duration
- 2h 30m
- Frequency
- 3 times a day
- Estimated price
- $23–140
- Website
- https://www.redcoachusa.com
- Web
- $23–140
Bus from West Palm Beach, FL to Fort Pierce
- Ave. Duration
- 46 min
- Frequency
- 3 times a day
- Estimated price
- $21–140
- Website
- https://www.redcoachusa.com
- Web
- $21–140
Bus from Fort Lauderdale Airport to Fort Pierce
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $22–140
- Website
- https://www.redcoachusa.com
- Web
- $22–140
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Summerland Key - Mote Marine Lab to Miami, FL - International Airport
- Ave. Duration
- 3h 30m
- Frequency
- 4 times a day
- Estimated price
- $130–180
- Website
- https://www.keysshuttle.com
Shuttle from Big Pine Key, FL to Fort Lauderdale, FL - International Airport
- Ave. Duration
- 3h 30m
- Frequency
- 4 times a day
- Estimated price
- $150–200
- Website
- https://www.keysshuttle.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Miami Airport Station to Port St Lucie
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Estimated price
- $17–85
- Schedules at
- flixbus.com
- Adult
- $17–85
- Phone
- +1 772-343-0217
- Website
- smartshuttleline.com
Shuttle from Orlando Airport to Fort Pierce, FL - Dunkin' Donuts
- Ave. Duration
- 1h 57m
- Frequency
- 4 times a day
- Estimated price
- $70–85
- Schedules at
- smartshuttleline.com
- one passenger
- $70–85
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