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How to get fromFlorida Keys to Orlandoby plane, bus, train, car, shuttle or bus (Greyhound, Flixbus)

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There are 8 ways to get from Florida Keys to Orlando by plane, bus, train, car, shuttle, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Key West International Airport to Orlando

    best
    1. Fly from Key West International Airport (EYW) to Orlando (MCO)plane plane EYW - MCO
    4h 20m
    $149–446

  2. Bus, train via West Palm Beach

    cheapest
    1. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    2. Take the train from Miami Airport Station to West Palm Beach Stationtrain train
    3. Take the bus from West Palm Beach, FL to Orlando - RedCoach Station, FLbus bus
    10h 51m
    $52–184

  3. Bus, train

    1. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    2. Take the train from Miami Airport Station to Fort Lauderdale Stationtrain train
    3. Take the train from Fort Lauderdale Amtrak Station to Orlandotrain train
    11h 58m
    $63–94

  4. Drive 355 mi

    1. Drive from Florida Keys to Orlandocar car 355 mi
    7h 19m
    $65–94

  5. Shuttle to Miami International Airport, fly to Orlando

    1. Take a shuttle bus from Big Pine Key, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Orlando (MCO)plane plane MIA - MCO
    7h 7m
    $234–536

  6. Bus to Key West International Airport, fly to Orlando Sanford

    1. Take the bus from Sugarloaf Key - Lower - Opposite Sugarloaf Lodge to Summerland Key - Mote Marine Labbus bus
    2. Fly from Key West International Airport (EYW) to Orlando Sanford (SFB)plane plane EYW - SFB
    4h 21m
    $202–564

  7. Bus

    1. Take the bus from Big Pine Key to Miami Airport Stationbus bus Greyhound US0720s
    2. Take the bus from Miami Airport Station to Orlandobus bus FlixBus 2411 / ...
    10h 52m
    $53–80

  8. Shuttle, bus

    1. Take a shuttle bus from Summerland Key - Mote Marine Lab to Miami, FL - International Airportshuttle bus To the Airports
    2. Take the bus from Miami International Airport to Orlandobus bus Miami Clarion to Orlando / ...
    11h 15m
    $180–224

Key West International Airport (EYW) to Orlando (MCO) flights

Calendar12Weekly Planes
Duration2h 21mAverage Duration
Ticket$51Cheapest Price
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Questions & Answers

What companies run services between Florida Keys, FL, USA and Orlando, FL, USA?

Breeze Airways and American Airlines fly from Key West International Airport (EYW) to Orlando (MCO) twice daily. Alternatively, you can take a vehicle from Florida Keys to Mccoy Rd & Central Ave via Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Orlando, and Florida Mall Ave & Crystal Clear Ln in around 10h 52m.

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