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How to get fromDurham to Lexingtonby plane, car, bus (Flixbus, Greyhound), train or bus (Greyhound)

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There are 7 ways to get from Durham to Lexington by plane, car, bus (Flixbus, Greyhound), train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Raleigh-Durham International Airport to Louisville International Airport, drive

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Louisville International Airport (SDF)planeRDU - SDF
    2. Drive from Louisville-Airport-SDF to Lexingtoncar
    5h 4m
    $154–414

  2. Drive 425.4 mi

    cheapest
    1. Drive from Durham to Lexingtoncar425.4 mi
    8h 23m
    $78–113

  3. Bus via Atlanta

    1. Take the bus from Durham to Atlanta DowntownbusFlixBus N2470
    2. Take the bus from Atlanta Bus Station to Lexington Bus StopbusGreyhound US0110
    15h 46m
    $135–280

  4. Fly Raleigh-Durham International Airport to Blue Grass Airport

    1. Fly from Raleigh-Durham International Airport (RDU) to Blue Grass Airport (LEX)planeRDU - LEX
    7h 58m
    $132–855

  5. Train to Charlotte Douglas International Airport, fly to Louisville International Airport, drive

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain
    2. Fly from Charlotte Douglas International Airport (CLT) to Louisville International Airport (SDF)planeCLT - SDF
    3. Drive from Louisville-Airport-SDF to Lexingtoncar
    7h 45m
    $132–479

  6. Bus

    1. Take the bus from Durham to Atlanta Bus StationbusFlixBus N2471 / ...
    2. Take the bus from Atlanta Bus Station to Lexington Bus StopbusGreyhound US0110
    15h 52m
    $129–278

  7. Bus #2

    1. Take the bus from Durham to Winston Salem(Trans Center)bus
    2. Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus
    3. Take the bus from Columbus - Downtown - Mound St to Greyhound Station Cincinnatibus
    4. Take the bus from Cincinnati Bus Station to Lexington Bus Stopbus
    18h 48m
    $97–230

Raleigh-Durham International Airport (RDU) to Louisville International Airport (SDF) flights

Calendar48Weekly Planes
Duration3h 38mAverage Duration
Ticket$88Cheapest Price
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Questions & Answers

What companies run services between Durham, NC, USA and Lexington, KY, USA?

You can take a bus from Durham to Lexington via Atlanta Downtown, Civic Center Station, Garnett Station, Atlanta Bus Station, and Lexington Bus Stop in around 15h 46m. Alternatively, American Airlines, Delta, and United Airlines fly from Raleigh-Durham International Airport (RDU) to Blue Grass Airport (LEX) hourly.

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