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How to get fromDurham to Lexingtonby car, plane or train

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There are 6 ways to get from Durham to Lexington by car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive 425.4 mi

    best
    1. Drive from Durham to Lexingtoncar car 425.4 mi
    8h 25m
    $78–113

  2. Fly Raleigh-Durham International Airport to Blue Grass Airport

    cheapest
    1. Fly from Raleigh-Durham International Airport (RDU) to Blue Grass Airport (LEX)plane plane RDU - LEX
    8h 8m
    $52–345

  3. Fly Raleigh-Durham International Airport to Louisville International Airport, drive

    1. Fly from Raleigh-Durham International Airport (RDU) to Louisville International Airport (SDF)plane plane RDU - SDF
    2. Drive from Louisville-Airport-SDF to Lexingtoncar car
    5h 10m
    $154–434

  4. Fly Raleigh-Durham International Airport to Covington, drive

    1. Fly from Raleigh-Durham International Airport (RDU) to Covington (CVG)plane plane RDU - CVG
    2. Drive from Covington (CVG) to Lexingtoncar car
    5h 16m
    $115–675

  5. Train to Charlotte Douglas International Airport, fly to Louisville International Airport, drive

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Louisville International Airport (SDF)plane plane CLT - SDF
    3. Drive from Louisville-Airport-SDF to Lexingtoncar car
    7h 51m
    $132–410

  6. Train to Charlotte Douglas International Airport, fly to Blue Grass Airport

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Blue Grass Airport (LEX)plane plane CLT - LEX
    8h 42m
    $80–331

Raleigh-Durham International Airport (RDU) to Louisville International Airport (SDF) flights

Calendar53Weekly Planes
Duration3h 49mAverage Duration
Ticket$83Cheapest Price
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Questions & Answers

What companies run services between Durham, NC, USA and Lexington, KY, USA?

American Airlines, Delta, and United Airlines fly from Raleigh-Durham International Airport (RDU) to Blue Grass Airport (LEX) hourly.

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