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How to get fromDuke University to Indianapolisby bus, plane, bus (Flixbus), train (Amtrak), car, train, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Duke University to Indianapolis by bus, plane, bus (Flixbus), train (Amtrak), car, train, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 6 bus, bus to Raleigh-Durham International Airport, fly

    best
    1. Take the bus from Flowers Dr at Duke Gardens to Durham Stationbus bus
    2. Take the bus from Durham Station to Regional Transit Centerbus bus
    3. Fly from Raleigh-Durham International Airport (RDU) to Indianapolis (IND)plane plane RDU - IND
    5h 52m
    $167–219

  2. Bus

    cheapest
    1. Take the bus from Columbia & Rosemary to Greensboro Depotbus bus 4
    2. Take the bus from Greensboro to Winston-Salembus bus
    3. Take the bus from Winston Salem to Columbusbus bus
    4. Take the bus from Columbus to Indianapolisbus bus
    19h 58m
    $80–152

  3. Train (Amtrak)

    1. Take the train from Durham Amtrak Station to Greensborotrain train
    2. Take the train from Greensboro to Charlottesvilletrain train
    3. Take the train from Charlottesville to Indianapolistrain train
    23h 8m
    $451–751

  4. Drive  586.3 mi

    1. Drive from Duke University to Indianapoliscar car 586.3 mi
    10h 26m
    $107–155

  5. Train to Piedmont Triad International Airport, fly

    1. Take the train from Durham Amtrak Station to Greensborotrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Indianapolis (IND)plane plane GSO - IND
    8h 30m
    $173–743

  6. Bus via Charlotte

    1. Take the bus from Durham to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte Bus Station to Columbusbus bus
    3. Take the bus from Columbus to Indianapolis Union Stationbus bus
    20h 9m
    $98–191

  7. Train via Arlington (Amtrak)

    1. Take the train from Durham Amtrak Station to Alexandriatrain train Carolinian
    2. Take the train from Alexandria to Indianapolistrain train Cardinal
    26h 48m
    $561–881

Duke University to Indianapolis by foot, bus, and train (Amtrak)

Calendar3Weekly Services
Duration23h 8mAverage Duration
Ticket$451Cheapest Price
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Comparing Your Travel Options

Map of how to get from Duke University to Indianapolis.ExpandLaunch map view
  • Distance: 521.9 mi
  • Duration: 5h 52m

What companies run services between Duke University, NC, USA and Indianapolis, IN, USA?

You can take a vehicle from Duke University to Indianapolis via Erwin Rd at Downing St, E Franklin St at Varsity Theatre, Columbia & Rosemary, Greensboro Depot, Greensboro, Winston Salem, Columbus, S Grant Ave & E Mound St, S High St & E Rich St, and Columbus in around 19h 58m. Alternatively, you can take a vehicle from Duke University to Indianapolis via Flowers Dr at Duke Gardens, Durham Station, Durham Amtrak Station, Greensboro, and Charlottesville in around 23h 8m.

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