There are 7 ways to get from Duke University to Indianapolis by bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Line 6 bus, line 700 bus to Raleigh-Durham International Airport, fly
best- Take the bus from Flowers Dr at Duke Gardens to Durham Stationbus
- Take the bus from Pettigrew St at Parking Deck to Regional Transit Centerbus
- Fly from Raleigh-Durham International Airport (RDU) to Indianapolis (IND)plane RDU - IND
5h 56m$113–366Bus
cheapest- Take the bus from Durham to Winston Salem(Trans Center)bus
- Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus
- Take the bus from Columbus to Indianapolisbus
17h 59m$72–159Train (Amtrak)
- Take the train from Durham Amtrak Station to Greensborotrain
- Take the train from Greensboro to Charlottesvilletrain
- Take the train from Charlottesville to Indianapolistrain
23h 8m$194–466Drive 587.2 mi
- Drive from Duke University to Indianapoliscar 587.2 mi
10h 25m$108–155Train to Piedmont Triad International Airport, fly
- Take the train from Durham Amtrak Station to Greensborotrain
- Fly from Piedmont Triad International Airport (GSO) to Indianapolis (IND)plane GSO - IND
9h 11m$110–529Bus, train
- Take the bus from Durham to Winston Salem(Trans Center)bus
- Take the bus from Winston Salem(Trans Center) to Ashlandbus
- Take the train from Ashland Amtrak Station to Indianapolistrain
18h 10m$106–246Train via Arlington (Amtrak)
- Take the train from Durham Amtrak Station to Alexandriatrain Carolinian
- Take the train from Alexandria to Indianapolistrain Cardinal
26h 48m$246–571
Duke University to Indianapolis by foot and bus
Questions & Answers
The cheapest way to get from Duke University to Indianapolis is to bus which costs $70 - $160 and takes 17h 59m.
The fastest way to get from Duke University to Indianapolis is to line 6 bus and line 700 bus and fly which takes 5h 56m and costs $110 - $370.
No, there is no direct bus from Duke University to Indianapolis. However, there are services departing from Flowers Dr at Duke Gardens and arriving at Indianapolis via Durham, Winston Salem(Trans Center), S Grant Ave & E Mound St and Columbus. The journey, including transfers, takes approximately 17h 59m.
The distance between Duke University and Indianapolis is 525 miles. The road distance is 590.6 miles.
The best way to get from Duke University to Indianapolis without a car is to bus which takes 17h 59m and costs $70 - $160.
It takes approximately 5h 56m to get from Duke University to Indianapolis, including transfers.
Duke University to Indianapolis bus services, operated by Greyhound USA, depart from Durham station.
The best way to get from Duke University to Indianapolis is to bus which takes 17h 59m and costs $70 - $160. Alternatively, you can train, which costs $190 - $470 and takes 23h 8m.
Duke University to Indianapolis bus services, operated by Greyhound USA, arrive at Winston Salem(Trans Center) station.
Yes, the driving distance between Duke University to Indianapolis is 591 miles. It takes approximately 10h 25m to drive from Duke University to Indianapolis.
What companies run services between Duke University, NC, USA and Indianapolis, IN, USA?
You can take a vehicle from Duke University to Indianapolis via Flowers Dr at Duke Gardens, Durham Station, Durham, Winston Salem(Trans Center), Columbus - Mound St, S Grant Ave & E Mound St, S High St & E Rich St, and Columbus in around 17h 59m. Alternatively, you can take a vehicle from Duke University to Indianapolis via Flowers Dr at Duke Gardens, Durham Station, Durham Amtrak Station, Greensboro, and Charlottesville in around 23h 8m.
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Indianapolis
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $65–400
Flights from Raleigh-Durham International Airport to Indianapolis via Atlanta
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $85–470
Flights from Piedmont Triad International Airport to Indianapolis via Atlanta
- Ave. Duration
- 4h 54m
- When
- Every day
- Estimated price
- $95–550
Flights from Piedmont Triad International Airport to Indianapolis via Detroit
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $95–550
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Indianapolis via Charlotte
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $70–420
Flights from Piedmont Triad International Airport to Indianapolis via Charlotte
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $80–480
Flights from Piedmont Triad International Airport to Indianapolis via Reagan Washington
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $100–550
Flights from Piedmont Triad International Airport to Indianapolis via Philadelphia
- Ave. Duration
- 5h 46m
- When
- Every day
- Estimated price
- $110–600
Flights from Piedmont Triad International Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 5h 31m
- When
- Every day
- Estimated price
- $100–550
- Website
- united.com
Flights from Raleigh-Durham International Airport to Indianapolis via Washington Dulles
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $80–450
Flights from Piedmont Triad International Airport to Indianapolis via Washington Dulles
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $95–550
Flights from Piedmont Triad International Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $100–550
- Website
- southwest.com
Flights from Raleigh-Durham International Airport to Indianapolis via Chicago Midway
- Ave. Duration
- 4h 5m
- When
- Tuesday and Wednesday
- Estimated price
- $85–470
Flights from Raleigh-Durham International Airport to Indianapolis via Baltimore
- Ave. Duration
- 4h 10m
- When
- Monday, Thursday, and Friday
- Estimated price
- $85–470
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Durham Amtrak Station to Greensboro
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $13–30
- Website
- https://www.amtrak.com/home.html
Train from Greensboro to Charlottesville
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $40–95
- Website
- https://www.amtrak.com/home.html
Train from Charlottesville to Indianapolis
- Ave. Duration
- 15h 23m
- Frequency
- 3 times a week
- Estimated price
- $140–340
- Website
- https://www.amtrak.com/home.html
Train from Ashland Amtrak Station to Indianapolis
- Ave. Duration
- 7h 1m
- Frequency
- 3 times a week
- Estimated price
- $65–150
- Website
- https://www.amtrak.com/home.html
Train from Durham Amtrak Station to Alexandria
- Ave. Duration
- 6h 33m
- Frequency
- Once daily
- Estimated price
- $75–180
- Website
- https://www.amtrak.com/home.html
Train from Alexandria to Indianapolis
- Ave. Duration
- 17h 56m
- Frequency
- 3 times a week
- Estimated price
- $170–390
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 919-485-7433
- Website
- godurhamtransit.org
Bus from Flowers Dr at Duke Gardens to Durham Station
- Ave. Duration
- 15 min
- Frequency
- Hourly
- Estimated price
- $1
- Schedules at
- godurhamtransit.org
- Phone
- +1 919 485 7433
- customerservice@gotriangle.org
- Website
- gotriangle.org
Bus from Pettigrew St at Parking Deck to Regional Transit Center
- Ave. Duration
- 40 min
- Frequency
- Every 30 minutes
- Website
- https://gotriangle.org/
- Schedules at
- https://gotriangle.org/maps-schedules/gotriangle
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Durham to Winston Salem(Trans Center)
- Ave. Duration
- 1h 35m
- Frequency
- 3 times a day
- Estimated price
- $13–25
- Website
- https://www.greyhound.com/
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Winston Salem(Trans Center) to Columbus - Mound St
- Ave. Duration
- 9h 20m
- Frequency
- Once daily
- Estimated price
- $35–90
- Website
- https://baronsbus.com
Bus from Winston Salem(Trans Center) to Ashland
- Ave. Duration
- 6h 15m
- Frequency
- Once daily
- Estimated price
- $27–70
- Website
- https://baronsbus.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Columbus to Indianapolis
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $21–40
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 874+ hotels available in Indianapolis.













