There are 5 ways to get from Charleston to Indianapolis by plane, bus, car or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  4 h 19 min

  1. Fly from Charleston (CHS) to Indianapolis (IND) CHS - IND

$127 - $387

Cheapest option

Bus Megabus  •  20 h 33 min

  1. Take the bus from Charleston, SC to Columbia, SC
  2. Take the bus from Columbia to Atlanta, GA - Marta Civic Center Station
  3. Take the bus from Marta Civic Center Station - Nb to Indianapolis, IN

$115 - $160

3 alternative options

Bus via Louisville, Ky  •  20 h 49 min

  1. Take the bus from Charleston, SC to Savannah, GA
  2. Take the bus from Savannah, Ga to Atlanta, Ga
  3. Take the bus from Atlanta, Ga to Louisville, Ky
  4. Take the bus from Louisville, KY to Indianapolis, IN - Amtrak

$120 - $258

Drive, train  •  30 h 18 min

  1. Drive from Charleston to Yemassee Amtrak
  2. Take the train from Yemassee Amtrak to Alexandria Amtrak
  3. Take the train from Alexandria Amtrak to Indianapolis Amtrak

$186 - $519

Drive  •  12 h 16 min

  1. Drive from Charleston to Indianapolis 733.6 miles

$70 - $110

Questions & Answers

The cheapest way to get from Charleston to Indianapolis is to drive which costs $70 - $110 and takes 12 h 16 min.

More details

The quickest way to get from Charleston to Indianapolis is to fly which costs $120 - $390 and takes 4 h 19 min.

More details

The distance between Charleston and Indianapolis is 598 miles. The road distance is 733.6 miles.

Get driving directions

It takes approximately 4 h 19 min to get from Charleston to Indianapolis, including transfers.

More details

No, there is no direct bus from Charleston to Indianapolis. However, there are services departing from Mary St / Meeting St and arriving at Indianapolis, IN - Amtrak via Charleston, SC, Savannah, Ga, Atlanta, Ga and Louisville, KY. The journey, including transfers, takes approximately 20 h 49 min.

More details

What companies run services between Charleston, SC, USA and Indianapolis, IN, USA?

Allegiant Air, Delta and three other airlines fly from Charleston to Indianapolis hourly. Alternatively, you can take a bus from Charleston to Indianapolis via N. Charleston SuperStop on Rivers Ave, Charleston, SC, Columbia, SC, Columbia, Atlanta, GA - Marta Civic Center Station, and Marta Civic Center Station - Nb in around 20 h 33 min.

Airlines
Delta
Website
delta.com
Flights from Charleston to Indianapolis via Atlanta
Ave. Duration
3 h 38 min
When
Every day
Estimated price
$130 - $700
Flights from Charleston to Indianapolis via Detroit
Ave. Duration
4 h 8 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$150 - $750
American Airlines
Website
aa.com
Flights from Charleston to Indianapolis via Charlotte
Ave. Duration
3 h 48 min
When
Every day
Estimated price
$140 - $700
Flights from Charleston to Indianapolis via Reagan Washington
Ave. Duration
4 h 10 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$160 - $750
Allegiant Air
Website
allegiantair.com
Flights from Charleston to Indianapolis
Ave. Duration
1 h 46 min
When
Monday and Friday
Estimated price
$100 - $360
Southwest Airlines
Website
southwest.com
Flights from Charleston to Indianapolis via Chicago Midway
Ave. Duration
4 h 5 min
When
Sunday
Estimated price
$170 - $700
United Airlines
Website
united.com
Flights from Charleston to Indianapolis via Washington Dulles
Ave. Duration
4 h 8 min
When
Every day
Estimated price
$170 - $800
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Yemassee Amtrak to Alexandria Amtrak
Ave. Duration
9 h 59 min
Frequency
Twice daily
Estimated price
$80 - $230
Website
amtrak.com
Coach Seat
$80 - $120
Flexi Coach Seat
$140 - $210
Business Coach Seat
$160 - $230
Room
$340 - $470
Train from Alexandria Amtrak to Indianapolis Amtrak
Ave. Duration
17 h 56 min
Frequency
3 times a week
Estimated price
$100 - $280
Website
amtrak.com
Coach Seat
$100 - $150
Flexi Coach Seat
$170 - $260
Business Coach Seat
$200 - $280
Room
$410 - $600
Bus operators
South Eastern Stages
Phone
+1 877.836.7607 / 404.591.2750
Email
info@sestages.com
Website
southeasternstages.com
Bus from Charleston, SC to Columbia, SC
Ave. Duration
2 h 25 min
Frequency
Once daily
Estimated price
$24 - $35
Schedules at
southeasternstages.com
Bus from Charleston, SC to Savannah, GA
Ave. Duration
2 h 18 min
Frequency
Once daily
Estimated price
$21 - $35
Schedules at
southeasternstages.com
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Columbia to Atlanta, GA - Marta Civic Center Station
Ave. Duration
3 h 40 min
Frequency
5 times a day
Estimated price
$21 - $35
Schedules at
us.megabus.com
Bus from Marta Civic Center Station - Nb to Indianapolis, IN
Ave. Duration
10 h 46 min
Frequency
Twice daily
Estimated price
$50 - $65
Schedules at
us.megabus.com
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Savannah, Ga to Atlanta, Ga
Ave. Duration
4 h 25 min
Frequency
Every 15 minutes
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $50
Flexible
$55 - $70
Bus from Atlanta, Ga to Louisville, Ky
Ave. Duration
8 h 55 min
Frequency
Hourly
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$80 - $110

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