There are 4 ways to get from Charleston to Indianapolis by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  4 h 19 min

  1. Fly from Charleston (CHS) to Indianapolis (IND) CHS - IND

$127 - $387

Cheapest option

Bus Megabus  •  22 h 7 min

  1. Take the bus from Charleston to Atlanta, GA Charleston
  2. Take the bus from Marta Civic Center Station - Nb to Delaware St & Market St Indianapolis

$99 - $134

2 alternative options

Bus Greyhound USA  •  24 h 14 min

  1. Take the bus from Charleston to Columbia, SC
  2. Take the bus from Columbia, Sc to Columbus, Oh
  3. Take the bus from Columbus, OH to Richmond, IN
  4. Take the bus from Richmond, IN to Indianapolis, IN

$107 - $238

Drive  •  12 h 16 min

  1. Drive from Charleston to Indianapolis 733.6 miles

$70 - $110

Questions & Answers

No, there is no direct bus from Charleston to Indianapolis. However, there are services departing from Charleston and arriving at Delaware St & Market St Indianapolis via Spring St and Marta Civic Center Station - Nb. The journey, including transfers, takes approximately 22 h 7 min.

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The distance between Charleston and Indianapolis is 598 miles. The road distance is 733.6 miles.

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The best way to get from Charleston to Indianapolis without a car is to bus which takes 22 h 7 min and costs .

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It takes approximately 4 h 19 min to get from Charleston to Indianapolis, including transfers.

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Charleston to Indianapolis bus services, operated by South Eastern Stages, depart from Charleston station.

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The best way to get from Charleston to Indianapolis is to fly which takes 4 h 19 min and costs . Alternatively, you can bus, which costs and takes 22 h 7 min.

Mode details

The quickest flight from Charleston Airport to Indianapolis Airport is the direct flight which takes 1 h 46 min.

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Charleston to Indianapolis bus services, operated by Megabus, arrive at Delaware St & Market St Indianapolis station.

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Yes, the driving distance between Charleston to Indianapolis is 734 miles. It takes approximately 12 h 16 min to drive from Charleston to Indianapolis.

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Allegiant Air, United Airlines, American Airlines and two other airlines offer flights from Charleston Airport to Indianapolis Airport.

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Map of how to get from Charleston to Indianapolis.
Launch map view
  • Distance: 597.8 miles
  • Duration: 4 h 19 min

What companies run services between Charleston, SC, USA and Indianapolis, IN, USA?

Allegiant Air, Delta and three other airlines fly from Charleston to Indianapolis hourly. Alternatively, you can take a bus from Charleston to Indianapolis via Atlanta, GA, Spring St, W Peachtree St @ Civic Center MARTA Station, and Marta Civic Center Station - Nb in around 22 h 7 min.

Airlines
Delta
Website
delta.com
Flights from Charleston to Indianapolis via Atlanta
Ave. Duration
3 h 46 min
When
Every day
Estimated price
$130 - $700
American Airlines
Website
aa.com
Flights from Charleston to Indianapolis via Charlotte
Ave. Duration
3 h 46 min
When
Every day
Estimated price
$140 - $700
Southwest Airlines
Website
southwest.com
Flights from Charleston to Indianapolis via Chicago Midway
Ave. Duration
4 h 3 min
When
Every day
Estimated price
$170 - $700
United Airlines
Website
united.com
Flights from Charleston to Indianapolis via Washington Dulles
Ave. Duration
3 h 58 min
When
Every day
Estimated price
$170 - $800
Allegiant Air
Website
allegiantair.com
Flights from Charleston to Indianapolis
Ave. Duration
1 h 46 min
When
Monday and Friday
Estimated price
$100 - $360
Bus operators
South Eastern Stages
Phone
+1 877.836.7607 / 404.591.2750
Email
info@sestages.com
Website
southeasternstages.com
Bus from Charleston to Atlanta, GA
Ave. Duration
9 h 5 min
Frequency
Once daily
Estimated price
$45 - $65
Schedules at
southeasternstages.com
Bus from Charleston to Columbia, SC
Ave. Duration
2 h 40 min
Frequency
Once daily
Estimated price
$23 - $40
Schedules at
southeasternstages.com
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Marta Civic Center Station - Nb to Delaware St & Market St Indianapolis
Ave. Duration
11 h 5 min
Frequency
Twice daily
Estimated price
$50 - $65
Book at
megabus.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Columbia, Sc to Columbus, Oh
Ave. Duration
16 h
Frequency
Every 30 minutes
Estimated price
$55 - $150
Website
greyhound.com
Economy
$55 - $95
Flexible
$110 - $150
Barons Bus
Phone
+1 888-378-3823
Website
baronsbus.com
Bus from Columbus, OH to Richmond, IN
Ave. Duration
2 h 10 min
Frequency
Once daily
Estimated price
$15 - $28
Book at
baronsbus.com
Bus from Richmond, IN to Indianapolis, IN
Ave. Duration
1 h 10 min
Frequency
Once daily
Estimated price
$13 - $25
Book at
baronsbus.com

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There are 239+ hotels available in Indianapolis. Prices start at $69 USD per night.

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The best way to get from Charleston to Charleston Airport is to Shuttle Bus which takes 30 min and costs .

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