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How to get fromDes Moines to Scrantonby plane, bus, train, bus (Greyhound, Flixbus) or car

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There are 8 ways to get from Des Moines to Scranton by plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Wilkes-Barre/Scranton International Airport

    best
    1. Fly from Des Moines (DSM) to Wilkes-Barre/Scranton International Airport (AVP)plane plane DSM - AVP
    4h 47m
    $218–971

  2. Fly to Newark Liberty International Airport, bus

    cheapest
    1. Fly from Des Moines (DSM) to Newark Liberty International Airport (EWR)plane plane DSM - EWR
    2. Take the bus from Newark Penn Station to Scrantonbus bus
    6h 21m
    $142–649

  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Syracuse Regional Transportation Centertrain train
    3. Take the bus from Syracuse Bus Station to Scranton Bus Stationbus bus
    25h 52m
    $240–520

  4. Bus

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Harrisburg Bus Stationbus bus
    3. Take the bus from Harrisburg, Pa to Scranton, Pabus bus 770
    29h 15m
    $172–340

  5. Drive 1,017.7 mi

    1. Drive from Des Moines to Scrantoncar car 1,017.7 mi
    16h 45m
    $186–269

  6. Fly to Lehigh Valley International Airport, bus

    1. Fly from Des Moines (DSM) to Lehigh Valley International Airport (ABE)plane plane DSM - ABE
    2. Take the bus from Lehigh Valley International Airport to Scranton Bus Stationbus bus
    8h 7m
    $172–797

  7. Fly to Philadelphia International Airport, bus

    1. Fly from Des Moines (DSM) to Philadelphia International Airport (PHL)plane plane DSM - PHL
    2. Take the bus from Philadelphia 30th St Station to Scrantonbus bus
    7h
    $231–949

  8. Bus, train via Saint Paul

    1. Take the bus from Des Moines to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Syracuse Regional Transportation Centertrain train
    4. Take the bus from Syracuse Bus Station to Scrantonbus bus
    30h 52m
    $300–732

Des Moines to Scranton by bus, foot, and train

Calendar7Weekly Services
Duration25h 52mAverage Duration
Ticket$240Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Scranton, PA, USA?

United Airlines and American Airlines fly from Des Moines (DSM) to Wilkes-Barre/Scranton International Airport (AVP) 5 times a day. Alternatively, you can take a bus from Des Moines to Scranton, Pa via Chicago Bus Station and Harrisburg, Pa in around 29h 15m.

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