There are 5 ways to get from Des Moines to Indianapolis by plane, bus (Greyhound, Flixbus), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Des Moines
best- Fly from Des Moines (DSM) to Indianapolis (IND)plane DSM - IND
4h 51m$130–723Bus
cheapest- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0123 / ...
- Take the bus from Chicago Bus Station to Indianapolisbus FlixBus N2640 / ...
11h 55m$75–139Drive 465.7 mi
- Drive from Des Moines to Indianapoliscar 465.7 mi
7h 53m$85–123Drive to Fort Dodge Municipal Airport, fly
- Drive from Des Moines to Fort Dodge Municipal Airport (FOD)car
- Fly from Fort Dodge Municipal Airport (FOD) to Indianapolis (IND)plane FOD - IND
6h 44m$84–437Bus, train
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0123 / ...
- Take the train from Chicago Union Station to Indianapolistrain Cardinal
13h 8m$94–199
Des Moines to Indianapolis by bus
Questions & Answers
The cheapest way to get from Des Moines to Indianapolis is to bus which costs $75 - $140 and takes 11h 55m.
The fastest way to get from Des Moines to Indianapolis is to fly which takes 4h 51m and costs $130 - $750.
No, there is no direct bus from Des Moines to Indianapolis. However, there are services departing from Des Moines and arriving at Indianapolis via Chicago Bus Station. The journey, including transfers, takes approximately 11h 55m.
The distance between Des Moines and Indianapolis is 429 miles. The road distance is 468.4 miles.
The best way to get from Des Moines to Indianapolis without a car is to bus which takes 11h 55m and costs $75 - $140.
It takes approximately 4h 51m to get from Des Moines to Indianapolis, including transfers.
Des Moines to Indianapolis bus services, operated by Greyhound USA, depart from Des Moines station.
The best way to get from Des Moines to Indianapolis is to fly which takes 4h 51m and costs $130 - $750. Alternatively, you can bus, which costs $75 - $140 and takes 11h 55m.
Des Moines to Indianapolis bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Indianapolis is 1h ahead of Des Moines. It is currently 10:22 AM in Des Moines and 11:22 AM in Indianapolis.
What companies run services between Des Moines, IA, USA and Indianapolis, IN, USA?
American Airlines, United Airlines, and two other airlines fly from Des Moines (DSM) to Indianapolis (IND) hourly. Alternatively, you can take a bus from Des Moines to Indianapolis via Chicago Bus Station in around 11h 55m.
- Website
- delta.com
Flights from Des Moines to Indianapolis via Minneapolis
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $140–800
Flights from Des Moines to Indianapolis via Detroit
- Ave. Duration
- 4h 22m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–800
Flights from Des Moines to Indianapolis via Atlanta
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $190–950
- Website
- united.com
Flights from Des Moines to Indianapolis via Chicago O'Hare
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $110–700
Flights from Fort Dodge Municipal Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $65–410
- Website
- aa.com
Flights from Des Moines to Indianapolis via Chicago O'Hare
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $110–700
Flights from Des Moines to Indianapolis via Charlotte
- Ave. Duration
- 5h 50m
- When
- Every day
- Estimated price
- $200–1,000
- Website
- southwest.com
Flights from Des Moines to Indianapolis via Chicago Midway
- Ave. Duration
- 5h 32m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–700
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $40–100
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $50–100
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to Indianapolis
- Ave. Duration
- 3h 50m
- Frequency
- Every 4 hours
- Estimated price
- $21–40
- Schedules at
- flixbus.com
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More Questions & Answers
Yes, the driving distance between Des Moines to Indianapolis is 468 miles. It takes approximately 7h 53m to drive from Des Moines to Indianapolis.
Book your Des Moines to Indianapolis bus tickets online with Omio and FlixBus.
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