There are 6 ways to get from Des Moines to Key Largo by plane, shuttle, bus (Greyhound, Flixbus), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Miami International Airport, shuttle
best- Fly from Des Moines (DSM) to Miami International Airport (MIA)plane DSM - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
5h 57m$268–981Bus
cheapest- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
43h 20m$182–518Bus, train, shuttle
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Miami Amtrak Stationtrain
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
2d 9h$321–839Drive 1,582.2 mi
- Drive from Des Moines to Key Largocar 1,582.2 mi
28h 3m$289–418Fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Des Moines (DSM) to Fort Lauderdale–Hollywood International Airport (FLL)plane DSM - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
6h 15m$248–811Fly to Key West International Airport, bus
- Fly from Des Moines (DSM) to Key West International Airport (EYW)plane DSM - EYW
- Take the bus from Key West Airport to Key Largo Bus Stopbus
9h 25m$277–1,181
Des Moines to Key Largo by bus
Questions & Answers
The cheapest way to get from Des Moines to Key Largo is to bus which costs $180 - $550 and takes 43h 20m.
The fastest way to get from Des Moines to Key Largo is to fly and shuttle which takes 5h 57m and costs $260 - $1,000.
No, there is no direct bus from Des Moines to Key Largo. However, there are services departing from Des Moines and arriving at Key Largo Bus Stop via Chicago Bus Station, Atlanta Bus Station and Miami Airport Station. The journey, including transfers, takes approximately 43h 20m.
The distance between Des Moines and Key Largo is 1400 miles. The road distance is 1591.5 miles.
The best way to get from Des Moines to Key Largo without a car is to bus which takes 43h 20m and costs $180 - $550.
It takes approximately 5h 57m to get from Des Moines to Key Largo, including transfers.
Des Moines to Key Largo bus services, operated by Greyhound USA, depart from Des Moines station.
Des Moines to Key Largo bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Key Largo is 1h ahead of Des Moines. It is currently 7:04 PM in Des Moines and 8:04 PM in Key Largo.
Yes, the driving distance between Des Moines to Key Largo is 1591 miles. It takes approximately 28h 3m to drive from Des Moines to Key Largo.
What companies run services between Des Moines, IA, USA and Key Largo, FL, USA?
You can take a bus from Des Moines to Key Largo Bus Stop via Chicago Bus Station, Atlanta Bus Station, and Miami Airport Station in around 43h 20m.
- Website
- delta.com
Flights from Des Moines to Miami International Airport via Atlanta
- Ave. Duration
- 6h 27m
- When
- Every day
- Estimated price
- $170–850
Flights from Des Moines to Fort Lauderdale–Hollywood International Airport via Atlanta
- Ave. Duration
- 5h 37m
- When
- Every day
- Estimated price
- $130–650
Flights from Des Moines to Key West International Airport via Atlanta
- Ave. Duration
- 7h 13m
- When
- Every day
- Estimated price
- $230–1,100
- Website
- aa.com
Flights from Des Moines to Miami International Airport
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- $170–850
Flights from Des Moines to Fort Lauderdale–Hollywood International Airport via Charlotte
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $130–650
Flights from Des Moines to Key West International Airport via Miami International Airport
- Ave. Duration
- 5h 33m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $240–1,200
Flights from Des Moines to Key West International Airport via Charlotte
- Ave. Duration
- 6h 14m
- When
- Every day
- Estimated price
- $250–1,200
- Website
- southwest.com
Flights from Des Moines to Miami International Airport via St. Louis
- Ave. Duration
- 5h 10m
- When
- Monday
- Estimated price
- $170–850
Flights from Des Moines to Fort Lauderdale–Hollywood International Airport via St. Louis
- Ave. Duration
- 5h 10m
- When
- Monday
- Estimated price
- $130–650
- Website
- allegiantair.com
Flights from Des Moines to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 18m
- When
- Thursday and Sunday
- Estimated price
- $130–650
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Miami Amtrak Station
- Ave. Duration
- 46h 29m
- Frequency
- Once daily
- Estimated price
- $170–600
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $80–110
- Website
- https://www.keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- $100–140
- Website
- https://www.keysshuttle.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $40–100
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 15m
- Frequency
- 4 times a day
- Estimated price
- $70–190
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 17h 20m
- Frequency
- Once daily
- Estimated price
- $65–210
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- 3 times a day
- Estimated price
- $13–22
- Website
- https://www.greyhound.com/
Bus from Key West Airport to Key Largo Bus Stop
- Ave. Duration
- 2h 40m
- Frequency
- 3 times a day
- Estimated price
- $29–60
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 14h 25m
- Frequency
- 3 times a day
- Estimated price
- $75–180
- Schedules at
- flixbus.com
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 13h 30m
- Frequency
- Once daily
- Estimated price
- $55–150
- Schedules at
- flixbus.com
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More Questions & Answers
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