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How to get fromDes Moines to Clevelandby plane, bus, train, car, bus (Greyhound), or bus (Greyhound, Amtrak)

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There are 6 ways to get from Des Moines to Cleveland by plane, bus, train, car, bus (Greyhound), or bus (Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE)plane plane DSM - CLE
    4h 14m
    $161–824

  2. Bus

    cheapest
    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the bus from Chicago to Clevelandbus bus Chicago
    15h
    $80–174

  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Cleveland Amtraktrain train Floridian / ...
    14h 19m
    $150–324

  4. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Cleveland Amtraktrain train
    15h 30m
    $181–398

  5. Drive 658.9 mi

    1. Drive from Des Moines to Clevelandcar car 658.9 mi
    10h 58m
    $121–174

  6. Bus via Toledo

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Union Station to Toledobus bus
    3. Take the bus from Toledo Bus Stop to Cleveland Bus Stationbus bus
    15h 38m
    $148–246

Des Moines to Cleveland by bus, foot, and train

Calendar21Weekly Services
Duration14h 19mAverage Duration
Ticket$150Cheapest Price
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Comparing Your Travel Options

Map of how to get from Des Moines to Cleveland.ExpandLaunch map view
  • Distance: 629.4 mi
  • Duration: 4h 14m

What companies run services between Des Moines, IA, USA and Cleveland, OH, USA?

Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE) hourly. Alternatively, you can take a bus from Des Moines to Cleveland via Chicago in around 15h.

Airlines
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