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How to get fromDes Moines to Clevelandby plane, bus, train, car, bus (Greyhound), or bus (Greyhound, Flixbus)

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There are 6 ways to get from Des Moines to Cleveland by plane, bus, train, car, bus (Greyhound), or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE)plane plane DSM - CLE
    4h 28m
    $181–924

  2. Bus

    cheapest
    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis, IN to Toledobus bus
    3. Take the bus from Toledo to Clevelandbus bus
    17h 20m
    $101–232

  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Cleveland Amtraktrain train Floridian / ...
    14h 19m
    $150–312

  4. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Cleveland Amtraktrain train
    15h 30m
    $181–387

  5. Drive 658.9 mi

    1. Drive from Des Moines to Clevelandcar car 658.9 mi
    10h 58m
    $121–174

  6. Bus via Chicago

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Robert K Pfaff Transit Center - Akronbus bus
    3. Take the bus from Robert K Pfaff Transit Center - Akron to W. Prospect Ave & Superior Avebus bus 61
    17h 36m
    $102–184

Des Moines to Cleveland by bus, foot, and train

Calendar19Weekly Services
Duration14h 19mAverage Duration
Ticket$150Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Cleveland.ExpandLaunch map view
  • Distance: 629.4 mi
  • Duration: 4h 28m

What companies run services between Des Moines, IA, USA and Cleveland, OH, USA?

Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE) hourly. Alternatively, you can take a bus from Des Moines to Cleveland via Indianapolis, IN and Toledo in around 17h 20m.

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Train operators
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