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How to get fromDes Moines to Clevelandby plane, bus, train, bus (Greyhound), car or bus (Greyhound, Flixbus)

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There are 8 ways to get from Des Moines to Cleveland by plane, bus, train, bus (Greyhound), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE)planeDSM - CLE
    4h 29m
    $171–874
  2. Bus

    cheapest
    1. Take the bus from Des Moines to ChicagobusOmaha
    2. Take the bus from Chicago Bus Station to Cleveland Bus StationbusGreyhound US0164
    14h 20m
    $98–228
  3. Bus, train

    1. Take the bus from Des Moines to ChicagobusOmaha
    2. Take the train from Chicago Union Station to Cleveland AmtraktrainFloridian / ...
    13h 24m
    $138–303
  4. Bus, train via Galesburg

    1. Take the bus from Des Moines to Burlingtonbus
    2. Take the bus from Burlington to Galesburgbus
    3. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
    4. Take the train from Chicago Union Station to Cleveland Amtraktrain
    16h
    $160–367
  5. Drive to Fort Dodge Municipal Airport, fly

    1. Drive from Des Moines to Fort Dodge Municipal Airport (FOD)car
    2. Fly from Fort Dodge Municipal Airport (FOD) to Cleveland-Hopkins International Airport (CLE)planeFOD - CLE
    6h 51m
    $110–528
  6. Bus, train via Des Moines

    1. Take the bus from Des Moines to ChicagobusDes Moines
    2. Take the train from Chicago Union Station to Cleveland AmtraktrainFloridian / ...
    14h 29m
    $126–314
  7. Bus via Detroit

    1. Take the bus from Des Moines to Chicago Bus Stationbus
    2. Take the bus from Chicago Bus Station to Detroit Bus Stationbus
    3. Take the bus from Detroit Bus Station to Cleveland Bus Stationbus
    18h 10m
    $115–245
  8. Drive 658.9 mi

    1. Drive from Des Moines to Clevelandcar658.9 mi
    10h 51m
    $121–174

Des Moines to Cleveland by bus, foot, and train

Calendar7Weekly Services
Duration13h 24mAverage Duration
Ticket$138Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Cleveland, OH, USA?

Delta, Southwest Airlines, and two other airlines fly from Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE) hourly. Alternatively, you can take a bus from Des Moines to Cleveland Bus Station via Chicago Bus Station in around 14h 20m.

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