Rome2Rio

How to get fromDes Moines to Clevelandby plane, bus, train, car, or bus (Greyhound)

Find Transport to Cleveland

See all options

There are 5 ways to get from Des Moines to Cleveland by plane, bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE)plane plane DSM - CLE
    4h 23m
    $181–974

  2. Bus

    cheapest
    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis, IN to Toledobus bus
    3. Take the bus from Toledo to Clevelandbus bus
    17h 20m
    $108–251

  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Cleveland Amtraktrain train Floridian / ...
    14h 19m
    $150–315

  4. Drive 658.9 mi

    1. Drive from Des Moines to Clevelandcar car 658.9 mi
    10h 58m
    $121–174

  5. Bus, train via Toledo

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Union Station to Toledobus bus
    3. Take the train from Toledo to Cleveland Amtraktrain train
    15h 8m
    $160–305

Des Moines to Cleveland by bus, foot, and train

Calendar19Weekly Services
Duration14h 19mAverage Duration
Ticket$150Cheapest Price
See schedules

Questions & Answers

What companies run services between Des Moines, IA, USA and Cleveland, OH, USA?

Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE) hourly. Alternatively, you can take a bus from Des Moines to Cleveland via Indianapolis, IN and Toledo in around 17h 20m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Trips from Des Moines

Trips to Cleveland

Popular routes