There are 6 ways to get from Des Moines to Cheyenne by plane, bus (Greyhound), car, taxi, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Cheyenne Airport
best- Fly from Des Moines (DSM) to Cheyenne Airport (CYS)plane DSM - CYS
5h 23m$128–671Drive 627.6 mi
cheapest- Drive from Des Moines to Cheyennecar 627.6 mi
9h 41m$115–166Bus via Omaha
- Take the bus from Des Moines to Omaha, NEbus
- Take the bus from Omaha, NE to Denverbus
- Take the bus from Denver International Airport Pickups to Warren AFBbus
17h 56m$228–350Fly to Laramie Regional Airport, taxi
- Fly from Des Moines (DSM) to Laramie Regional Airport (LAR)plane DSM - LAR
- Take the taxi from Laramie-Airport-LAR to Cheyennetaxi
5h 28m$238–791Fly to Denver, bus
- Fly from Des Moines (DSM) to Denver (DEN)plane DSM - DEN
- Take the bus from Denver International Airport Pickups to Warren AFBbus
5h 37m$218–961Bus
- Take the bus from Des Moines to Denver Union Stationbus Greyhound US0123
- Take the bus from Denver International Airport Pickups to Warren AFBbus Groome Transportation - Wyoming
18h 16m$133–254
Des Moines (DSM) to Cheyenne Airport (CYS) flights
Questions & Answers
The cheapest way to get from Des Moines to Cheyenne is to drive which costs $110 - $170 and takes 9h 41m.
The fastest way to get from Des Moines to Cheyenne is to fly which takes 5h 23m and costs $120 - $700.
The distance between Des Moines and Cheyenne is 590 miles. The road distance is 631.2 miles.
The best way to get from Des Moines to Cheyenne without a car is to bus via Omaha which takes 17h 56m and costs $220 - $350.
It takes approximately 5h 23m to get from Des Moines to Cheyenne, including transfers.
The best way to get from Des Moines to Cheyenne is to fly which takes 5h 23m and costs $120 - $700. Alternatively, you can bus via Omaha, which costs $220 - $350 and takes 17h 56m.
Cheyenne is 1h behind Des Moines. It is currently 8:59 AM in Des Moines and 7:59 AM in Cheyenne.
Yes, the driving distance between Des Moines to Cheyenne is 631 miles. It takes approximately 9h 41m to drive from Des Moines to Cheyenne.
There are 61+ hotels available in Cheyenne.
What companies run services between Des Moines, IA, USA and Cheyenne, WY, USA?
United Airlines flies from Des Moines (DSM) to Cheyenne Airport (CYS) 5 times a day. Alternatively, you can take a bus from Des Moines to Warren AFB via Omaha, NE, Denver, Union Station, Denver Airport Station, and Denver International Airport Pickups in around 17h 56m.
- Website
- united.com
Flights from Des Moines to Cheyenne Airport via Denver
- Ave. Duration
- 7h 17m
- When
- Every day
- Estimated price
- $110–650
Flights from Des Moines to Cheyenne Airport via Chicago O'Hare, Denver
- Ave. Duration
- 7h 24m
- When
- Every day
- Estimated price
- $170–850
Flights from Des Moines to Laramie Regional Airport via Denver
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $120–650
Flights from Des Moines to Denver
- Ave. Duration
- 2h 16m
- When
- Every day
- Estimated price
- $150–850
- Website
- delta.com
Flights from Des Moines to Denver via Minneapolis
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $190–1,000
- Website
- flyfrontier.com
Flights from Des Moines to Denver
- Ave. Duration
- 2h 12m
- When
- Monday and Friday
- Estimated price
- $150–850
- Website
- southwest.com
Flights from Des Moines to Denver
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- $150–850
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Omaha, NE
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $28–70
- Website
- https://www.greyhound.com/
Bus from Des Moines to Denver Union Station
- Ave. Duration
- 14h
- Frequency
- Once daily
- Estimated price
- $70–160
- Website
- https://www.greyhound.com/
- Phone
- +1-877-779-2999
- tony@expressarrow.com
- Website
- expressarrow.com
Bus from Omaha, NE to Denver
- Ave. Duration
- 10h 20m
- Frequency
- Once daily
- Estimated price
- $140–180
- Website
- https://expressarrow.com
- Phone
- +1 970-226-5533
- Website
- groometransportation.com
Bus from Denver International Airport Pickups to Warren AFB
- Ave. Duration
- 2h 20m
- Frequency
- Every 4 hours
- Estimated price
- $50–90
- Website
- https://groometransportation.com/denver-airport
- Schedules at
- https://groometransportation.com/wyoming
- Ave. Duration
- 55 min
- Estimated price
- $100–120
Snowy Range Taxi
- Phone
- +1-307-343-2323
- Website
- snowyrangetaxi.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide




