There are 7 ways to get from Des Moines to Cheyenne by plane, bus (Greyhound), bus, taxi, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Des Moines to Cheyenne Airport
best- Fly from Des Moines (DSM) to Cheyenne Airport (CYS)plane DSM - CYS
5h 19m$118–621Drive to Fort Dodge Municipal Airport, fly to Cheyenne Airport
cheapest- Drive from Des Moines to Fort Dodge Municipal Airport (FOD)car
- Fly from Fort Dodge Municipal Airport (FOD) to Cheyenne Airport (CYS)plane FOD - CYS
6h 17m$82–395Bus
- Take the bus from Des Moines to Kansas Citybus
- Take the bus from Kansas City Bus Station to Denver Union Stationbus
- Take the bus from Denver International Airport Pickups to Warren AFBbus
20h 11m$188–398Bus, taxi, train
- Take the bus from Des Moines to Moline Center Stationbus
- Take the taxi from Kennedy Sq Shelter to Galesburg Amtrak Stationtaxi
- Take the train from Galesburg Amtrak Station to Denvertrain
- Take the bus from Denver Union Station to Cheyennebus
26h 31m$426–797Drive 627.6 mi
- Drive from Des Moines to Cheyennecar 627.6 mi
9h 41m$115–166Fly Des Moines to Laramie Regional Airport, taxi
- Fly from Des Moines (DSM) to Laramie Regional Airport (LAR)plane DSM - LAR
- Take the taxi from Laramie-Airport-LAR to Cheyennetaxi
5h 15m$228–791Fly Des Moines to Denver, bus
- Fly from Des Moines (DSM) to Denver (DEN)plane DSM - DEN
- Take the bus from Denver International Airport Pickups to Warren AFBbus
5h 27m$188–861
Des Moines (DSM) to Cheyenne Airport (CYS) flights
Questions & Answers
The cheapest way to get from Des Moines to Cheyenne is to drive which costs $110 - $170 and takes 9h 41m.
The fastest way to get from Des Moines to Cheyenne is to fly and taxi which takes 5h 15m and costs $220 - $800.
The distance between Des Moines and Cheyenne is 590 miles. The road distance is 631.2 miles.
The best way to get from Des Moines to Cheyenne without a car is to bus which takes 20h 11m and costs $180 - $400.
It takes approximately 5h 19m to get from Des Moines to Cheyenne, including transfers.
The best way to get from Des Moines to Cheyenne is to fly which takes 5h 19m and costs $110 - $650. Alternatively, you can bus, which costs $180 - $400 and takes 20h 11m.
Cheyenne is 1h behind Des Moines. It is currently 12:34 AM in Des Moines and 11:34 PM in Cheyenne.
Yes, the driving distance between Des Moines to Cheyenne is 631 miles. It takes approximately 9h 41m to drive from Des Moines to Cheyenne.
There are 127+ hotels available in Cheyenne.
What companies run services between Des Moines, IA, USA and Cheyenne, WY, USA?
United Airlines and Southwest Airlines fly from Des Moines (DSM) to Cheyenne Airport (CYS) 3 times a day. Alternatively, you can take a bus from Des Moines to Warren AFB via Kansas City Bus Station, Denver Union Station, Union Station, Denver Airport Station, and Denver International Airport Pickups in around 20h 11m.
- Website
- united.com
Flights from Des Moines to Cheyenne Airport via Denver
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $100–600
Flights from Des Moines to Cheyenne Airport via Chicago O'Hare, Denver
- Ave. Duration
- 7h 36m
- When
- Saturday
- Estimated price
- $160–800
Flights from Des Moines to Laramie Regional Airport via Denver
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $110–650
Flights from Des Moines to Laramie Regional Airport via Chicago O'Hare, Denver
- Ave. Duration
- 7h 38m
- When
- Every day
- Estimated price
- $160–850
Flights from Des Moines to Denver
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- $120–750
Flights from Fort Dodge Municipal Airport to Cheyenne Airport via Denver
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $65–370
Flights from Fort Dodge Municipal Airport to Cheyenne Airport via Chicago O'Hare, Denver
- Ave. Duration
- 8h 21m
- When
- Every day
- Estimated price
- $100–500
- Website
- delta.com
Flights from Des Moines to Denver via Minneapolis
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $160–900
- Website
- southwest.com
Flights from Des Moines to Denver
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $120–750
- Website
- flyfrontier.com
Flights from Des Moines to Denver
- Ave. Duration
- 2h 9m
- When
- Monday and Friday
- Estimated price
- $120–750
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Galesburg Amtrak Station to Denver
- Ave. Duration
- 16h 13m
- Frequency
- Once daily
- Estimated price
- $250–550
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $18–90
- Book at
- https://www.jeffersonlines.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Kansas City Bus Station to Denver Union Station
- Ave. Duration
- 11h 25m
- Frequency
- Once daily
- Estimated price
- $110–210
- Website
- https://www.greyhound.com/
Bus from Des Moines to Moline Center Station
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $30–60
- Website
- https://www.greyhound.com/
Bus from Denver Union Station to Cheyenne
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- https://www.greyhound.com/
- Phone
- +1 970-226-5533
- Website
- groometransportation.com
Bus from Denver International Airport Pickups to Warren AFB
- Ave. Duration
- 2h 20m
- Frequency
- Every 4 hours
- Estimated price
- $50–90
- Website
- https://groometransportation.com/denver-airport
- Schedules at
- https://groometransportation.com/wyoming
- Phone
- +1-877-779-2999
- tony@expressarrow.com
- Website
- expressarrow.com
Bus from Denver Union Station to Cheyenne
- Ave. Duration
- 2h 15m
- Frequency
- 4 times a week
- Estimated price
- $45–60
- Website
- https://expressarrow.com
- Ave. Duration
- 52 min
- Estimated price
- $100–130
Larry's Cab
- Phone
- +1 563-388-7179
Good to Go Taxi Cab Service
- Phone
- +1 563-424-2039
- Website
- goodtogotaxi.com
Dana's Cabs
- Phone
- +1 563-323-2227
- Website
- danascabs.com
Snowy Range Taxi
- Phone
- +1-307-343-2323
- Website
- snowyrangetaxi.com
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