There are 8 ways to get from Lyon to Mainz by train (TGV), bus, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Mannheim
best- Take the train from Lyon Part Dieu to Mannheim Hbftrain Tgv
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
6h 56m€147–234Bus, train
cheapest- Take the bus from Lyon to Mannheim central bus stationbus FlixBus N122 / ...
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
11h 54m€61–114Bus
- Take the bus from LYON, Lyon - Perrache - poziom górny A to FRANKFURT AM MAIN, Hbf Südseite - Pforzheimer Str.bus
11h 50m€65–130Drive 653.1 km
- Drive from Lyon to Mainzcar 653.1 km
6h 2m€100–145Fly Lyon–Saint Exupéry Airport to Frankfurt
- Fly from Lyon–Saint Exupéry Airport (LYS) to Frankfurt (FRA)plane LYS - FRA
4h 38m€132–318Train
- Take the train from Lyon Part Dieu to Mannheim, Hauptbahnhoftrain 84
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
8h 40m€162–359Train to Geneva International Airport, fly to Frankfurt
- Take the train from Lyon Part Dieu to Genevetrain
- Fly from Geneva International Airport (GVA) to Frankfurt (FRA)plane GVA - FRA
6h 21m€154–337Fly Lyon–Saint Exupéry Airport to Düsseldorf International Airport, train
- Fly from Lyon–Saint Exupéry Airport (LYS) to Düsseldorf International Airport (DUS)plane LYS - DUS
- Take the train from Düsseldorf Hbf to Frankfurttrain
6h 29m€110–339
Lyon to Mainz by train
Questions & Answers
The cheapest way to get from Lyon to Mainz is to bus and train which costs €60 - €120 and takes 11h 54m.
The fastest way to get from Lyon to Mainz is to fly which takes 4h 38m and costs €130 - €320.
No, there is no direct bus from Lyon to Mainz station. However, there are services departing from LYON, Lyon - Perrache - poziom górny A and arriving at Mainz central train station via Frankfurt central train station. The journey, including transfers, takes approximately 11h 50m.
No, there is no direct train from Lyon to Mainz. However, there are services departing from Lyon Part Dieu and arriving at Mainz, Römisches Theater via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 6h 56m.
The distance between Lyon and Mainz is 709 km. The road distance is 653.1 km.
The best way to get from Lyon to Mainz without a car is to train via Mannheim which takes 6h 56m and costs €140 - €240.
It takes approximately 6h 56m to get from Lyon to Mainz, including transfers.
Lyon to Mainz bus services, operated by Sindbad, depart from LYON, Lyon - Perrache - poziom górny A station.
Lyon to Mainz train services, operated by TGV inOui, depart from Lyon Part Dieu station.
The best way to get from Lyon to Mainz is to train via Mannheim which takes 6h 56m and costs €140 - €240. Alternatively, you can bus, which costs €65 - €130 and takes 11h 50m, you could also fly, which costs €130 - €320 and takes 4h 38m.
What companies run services between Lyon, France and Mainz, Germany?
You can take a train from Lyon Part Dieu to Mainz, Römisches Theater via Mannheim Hbf and Mannheim, Hauptbahnhof in around 6h 56m. Alternatively, Sindbad operates a bus from LYON, Lyon - Perrache - poziom górny A to FRANKFURT AM MAIN, Hbf Südseite - Pforzheimer Str. twice a week. Tickets cost €60–130 and the journey takes 10h 10m.
- Website
- lufthansa.com
Flights from Lyon–Saint Exupéry Airport to Frankfurt
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €95–450
Flights from Lyon–Saint Exupéry Airport to Frankfurt via Munich
- Ave. Duration
- 3h 22m
- When
- Every day
- Estimated price
- €95–270
Flights from Geneva International Airport to Frankfurt
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €70–390
Flights from Geneva International Airport to Frankfurt via Munich
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €95–270
Flights from Lyon–Saint Exupéry Airport to Düsseldorf International Airport via Frankfurt
- Ave. Duration
- 3h 16m
- When
- Every day
- Estimated price
- €110–240
Flights from Lyon–Saint Exupéry Airport to Düsseldorf International Airport via Munich
- Ave. Duration
- 3h 30m
- When
- Thursday and Saturday
- Estimated price
- €110–240
- Website
- swiss.com
Flights from Geneva International Airport to Frankfurt
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €70–390
Flights from Geneva International Airport to Frankfurt via Zurich
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- €70–420
- Website
- brusselsairlines.com
Flights from Lyon–Saint Exupéry Airport to Frankfurt via Brussels
- Ave. Duration
- 3h 35m
- When
- Monday, Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- €70–260
Flights from Geneva International Airport to Frankfurt via Brussels
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €65–250
- Website
- airdolomiti.it
Flights from Lyon–Saint Exupéry Airport to Frankfurt
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €110–450
Flights from Geneva International Airport to Frankfurt
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €100–390
- Website
- airfrance.com
Flights from Lyon–Saint Exupéry Airport to Frankfurt via Paris Charles de Gaulle
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €45–300
Flights from Lyon–Saint Exupéry Airport to Düsseldorf International Airport via Paris Charles de Gaulle
- Ave. Duration
- 3h 30m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €45–300
- Website
- eurowings.com
Flights from Lyon–Saint Exupéry Airport to Düsseldorf International Airport
- Ave. Duration
- 1h 25m
- When
- Monday to Friday
- Estimated price
- €55–220
- Website
- klm.com
Flights from Lyon–Saint Exupéry Airport to Düsseldorf International Airport via Amsterdam Schiphol
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €50–310
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Lyon Part Dieu to Mannheim Hbf
- Ave. Duration
- 5h 17m
- Frequency
- Once daily
- Estimated price
- €130–210
- Website
- https://www.sncf-connect.com/en-en
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a week
- Estimated price
- €30–55
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €19–27
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 57 min
- Frequency
- 5 times a week
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Lyon Part Dieu to Mannheim, Hauptbahnhof
- Ave. Duration
- 7h 1m
- Frequency
- Once a week
- Estimated price
- €140–340
- Website
- https://int.bahn.de/en
Train from Düsseldorf Hbf to Frankfurt
- Ave. Duration
- 1h 17m
- Frequency
- Every 30 minutes
- Estimated price
- €40–90
- Website
- https://int.bahn.de/en
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 2h
- Frequency
- Every 3 hours
- Estimated price
- €25–60
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Düsseldorf Hbf to Frankfurt
- Ave. Duration
- 1h 27m
- Frequency
- Hourly
- Estimated price
- €22–55
- Website
- https://www.ns.nl/en
- Phone
- +48 801 22 33 44
- bilety@sindbad.pl
- Website
- sindbad.pl
Bus from LYON, Lyon - Perrache - poziom górny A to FRANKFURT AM MAIN, Hbf Südseite - Pforzheimer Str.
- Ave. Duration
- 10h 10m
- Frequency
- Twice a week
- Estimated price
- €60–130
- Website
- https://www.sindbad.pl/en/home
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Lyon to Mannheim central bus station
- Ave. Duration
- 10h 15m
- Frequency
- Twice daily
- Estimated price
- €45–80
- Website
- https://www.flixbus.co.uk
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Lyon to Mannheim central bus station
- Ave. Duration
- 9h 20m
- Frequency
- 4 times a week
- Estimated price
- €45–90
- Website
- https://www.blablacar.co.uk/bus
Want to know more about travelling around Germany
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
More Questions & Answers
Lyon to Mainz bus services, operated by Sindbad, arrive at FRANKFURT AM MAIN, Hbf Südseite - Pforzheimer Str. station.
Lyon to Mainz train services, operated by TGV inOui, arrive at Mannheim Hbf station.
Yes, the driving distance between Lyon to Mainz is 653 km. It takes approximately 6h 2m to drive from Lyon to Mainz.
Book your Lyon to Mainz train tickets online with Omio.
Book your Lyon to Mainz bus tickets online with Omio.
There are 413+ hotels available in Mainz.












































