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How to get fromLyon to Mainzby train (TGV), bus, car, plane, or train

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There are 7 ways to get from Lyon to Mainz by train (TGV), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Lyon Part Dieu to Mannheim Hbftrain train Tgv
    2. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train S5 / ...
    6h 54m
    €137–199

  2. Bus, train

    cheapest
    1. Take the bus from Lyon to Mannheim central bus stationbus bus N7720 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    11h 15m
    €60–103

  3. Bus

    1. Take the bus from LYON, Lyon - Perrache - poziom górny A to FRANKFURT AM MAIN, Hbf Südseite - Pforzheimer Str.bus bus
    10h 46m
    €107

  4. Drive  653.1 km

    1. Drive from Lyon to Mainzcar car 653.1 km
    6h 3m
    €120–173

  5. Fly Lyon–Saint Exupéry Airport to Frankfurt

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Frankfurt (FRA)plane plane LYS - FRA
    4h 35m
    €130–349

  6. Train to Geneva International Airport, fly to Frankfurt

    1. Take the train from Lyon Part Dieu to Genevetrain train
    2. Fly from Geneva International Airport (GVA) to Frankfurt (FRA)plane plane GVA - FRA
    6h 19m
    €147–334

  7. Fly Lyon–Saint Exupéry Airport to Strasbourg International Airport, train

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Strasbourg International Airport (SXB)plane plane LYS - SXB
    2. Take the train from Strasbourg to Mannheim Hbftrain train
    3. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train
    6h 48m
    €150–395

Lyon to Mainz by train

Calendar14Weekly Trains
Duration6h 54mAverage Duration
Ticket€137Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lyon to Mainz.ExpandLaunch map view
  • Distance: 710.4 km
  • Duration: 6h 54m

What companies run services between Lyon, France and Mainz, Germany?

You can take a train from Lyon Part Dieu to Mainz, Hauptbahnhof via Mannheim Hbf and Mannheim, Hauptbahnhof in around 6h 54m. Alternatively, Sindbad operates a bus from LYON, Lyon - Perrache - poziom górny A to FRANKFURT AM MAIN, Hbf Südseite - Pforzheimer Str. twice a week. Tickets cost €96 and the journey takes 10h 10m.

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