There are 7 ways to get from Lyon to Mainz by train (TGV), bus, train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Lyon Part Dieu to Mannheim Hbftrain Tgv
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
6h 57m€152–236Bus
cheapest- Take the bus from Lyon - Gerland Bus Station to Frankfurt - Airport Bus Stationbus BlaBlaCar Bus
11h 51m€69–127Bus, train
- Take the bus from Lyon to Saarbrücken bus stationbus N235
- Take the train from Saarbrücken Hbf to Mainz, Römisches Theatertrain Re3
11h 4m€73–116Drive 653.1 km
- Drive from Lyon to Mainzcar 653.1 km
6h 2m€102–147Fly from Lyon–Saint Exupéry Airport
- Fly from Lyon–Saint Exupéry Airport (LYS) to Frankfurt (FRA)plane LYS - FRA
4h 34m€131–289Train via Strasbourg
- Take the train from Lyon Part Dieu to Strasbourgtrain Tgv
- Take the train from Strasbourg to Mannheim Hbftrain Ice / ...
- Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain 55 / ...
7h 14m€146–335Train to Geneva International Airport, fly
- Take the train from Lyon Part Dieu to Genevetrain
- Fly from Geneva International Airport (GVA) to Frankfurt (FRA)plane GVA - FRA
6h 19m€155–325
Lyon to Mainz by train
Questions & Answers
The cheapest way to get from Lyon to Mainz is to bus which costs €65 - €130 and takes 11h 51m.
The fastest way to get from Lyon to Mainz is to fly which takes 4h 34m and costs €130 - €290.
No, there is no direct bus from Lyon station to Mainz. However, there are services departing from Lyon - Gerland Bus Station and arriving at Ginsheim-Gustavsburg-Gustavsburg Am Alten Fährhaus via Frankfurt. The journey, including transfers, takes approximately 11h 51m.
No, there is no direct train from Lyon to Mainz. However, there are services departing from Lyon Part Dieu and arriving at Mainz, Römisches Theater via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 6h 57m.
The distance between Lyon and Mainz is 709 km. The road distance is 653.1 km.
The best way to get from Lyon to Mainz without a car is to train which takes 6h 57m and costs €150 - €240.
It takes approximately 6h 57m to get from Lyon to Mainz, including transfers.
Lyon to Mainz bus services, operated by BlaBlaCar Bus, depart from Lyon - Gerland Bus Station.
Lyon to Mainz train services, operated by TGV inOui, depart from Lyon Part Dieu station.
The best way to get from Lyon to Mainz is to train which takes 6h 57m and costs €150 - €240. Alternatively, you can fly, which costs €130 - €290 and takes 4h 34m, you could also bus, which costs €65 - €130 and takes 11h 51m.
What companies run services between Lyon, France and Mainz, Germany?
You can take a train from Lyon Part Dieu to Mainz, Römisches Theater via Mannheim Hbf and Mannheim, Hauptbahnhof in around 6h 57m. Alternatively, Lufthansa, Air Dolomiti, and Air France fly from Lyon–Saint Exupéry Airport (LYS) to Frankfurt (FRA) every 4 hours.
- Website
- lufthansa.com
Flights from Lyon–Saint Exupéry Airport to Frankfurt
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €100–490
Flights from Lyon–Saint Exupéry Airport to Frankfurt via Munich
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €100–200
Flights from Geneva International Airport to Frankfurt
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- €100–460
Flights from Geneva International Airport to Frankfurt via Munich
- Ave. Duration
- 3h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- €100–210
- Website
- swiss.com
Flights from Geneva International Airport to Frankfurt
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- €100–460
Flights from Geneva International Airport to Frankfurt via Zurich
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- €120–490
- Website
- airdolomiti.it
Flights from Lyon–Saint Exupéry Airport to Frankfurt
- Ave. Duration
- 1h 25m
- When
- Monday, Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- €120–490
Flights from Geneva International Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- €120–460
- Website
- brusselsairlines.com
Flights from Geneva International Airport to Frankfurt via Brussels
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €200–270
- Website
- airfrance.com
Flights from Lyon–Saint Exupéry Airport to Frankfurt via Paris Charles de Gaulle
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €50–280
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Lyon Part Dieu to Mannheim Hbf
- Ave. Duration
- 5h 17m
- Frequency
- Twice daily
- Estimated price
- €130–220
- Website
- https://www.sncf-connect.com/en-en
Train from Lyon Part Dieu to Strasbourg
- Ave. Duration
- 4h 12m
- Frequency
- Hourly
- Estimated price
- €100–170
- Website
- https://www.sncf-connect.com/en-en
Train from Strasbourg to Mannheim Hbf
- Ave. Duration
- 1h 23m
- Frequency
- 4 times a day
- Estimated price
- €30–50
- Website
- https://www.sncf-connect.com/en-en
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- €35–55
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €13–20
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 1h 23m
- Frequency
- Hourly
- Estimated price
- €13–20
- Website
- https://int.bahn.de/en
- Phone
- +49 621 830 1200
- Website
- suewex.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 57 min
- Frequency
- Once daily
- Estimated price
- €14–20
- Schedules at
- suewex.de
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 52 min
- Frequency
- Every 4 hours
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +49 6731 999 27-27
- info@vlexx.de
- Website
- vlexx.de
Train from Saarbrücken Hbf to Mainz, Römisches Theater
- Ave. Duration
- 2h 22m
- Frequency
- Every 2 hours
- Estimated price
- €29–45
- Schedules at
- vlexx.de
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Strasbourg to Mannheim Hbf
- Ave. Duration
- 1h 8m
- Frequency
- Every 4 hours
- Estimated price
- €25–110
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Every 3 hours
- Estimated price
- €12–55
- Website
- https://int.bahn.de/en
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 2h 2m
- Frequency
- Hourly
- Estimated price
- €28–55
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Lyon to Saarbrücken bus station
- Ave. Duration
- 7h 20m
- Frequency
- Once daily
- Estimated price
- €40–75
- Website
- https://www.flixbus.co.uk
Bus from Lyon - Gerland Bus Station to Frankfurt - Airport Bus Station
- Ave. Duration
- 10h 5m
- Frequency
- Twice daily
- Estimated price
- €60–110
- Website
- https://www.flixbus.co.uk
- Phone
- +3 318 576 2228
- Website
- blablacar.co.uk
Bus from Lyon - Gerland Bus Station to Frankfurt - Airport Bus Station
- Ave. Duration
- 10h 50m
- Frequency
- Every 4 hours
- Estimated price
- €65–120
- Website
- https://www.blablacar.co.uk/bus
Want to know more about travelling around Germany
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
More Questions & Answers
Lyon to Mainz bus services, operated by BlaBlaCar Bus, arrive at Frankfurt - Airport Bus Station.
Lyon to Mainz train services, operated by TGV inOui, arrive at Mannheim Hbf station.
Yes, the driving distance between Lyon to Mainz is 653 km. It takes approximately 6h 2m to drive from Lyon to Mainz.
Book your Lyon to Mainz train tickets online with Omio.
Book your Lyon to Mainz bus tickets online with Omio.
There are 1213+ hotels available in Mainz.

































