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How to get fromLyon to Mainzby train (TGV), bus, train, car, or plane

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There are 6 ways to get from Lyon to Mainz by train (TGV), bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Lyon Part Dieu to Mannheim Hbftrain train Tgv
    2. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train S5 / ...
    6h 55m
    €140–233

  2. Bus

    cheapest
    1. Take the bus from Lyon - Gerland Bus Station to Frankfurt - Airport Bus Stationbus bus BlaBlaCar Bus
    12h 32m
    €60–104

  3. Bus, train

    1. Take the bus from Lyon to Saarbrücken bus stationbus bus N235
    2. Take the train from Saarbrücken Hbf to Mainz, Römisches Theatertrain train Re3
    11h 11m
    €74–112

  4. Drive  653.1 km

    1. Drive from Lyon to Mainzcar car 653.1 km
    6h 2m
    €105–151

  5. Fly from Lyon–Saint Exupéry Airport

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Frankfurt (FRA)plane plane LYS - FRA
    4h 35m
    €130–313

  6. Train to Geneva International Airport, fly

    1. Take the train from Lyon Part Dieu to Genevetrain train
    2. Fly from Geneva International Airport (GVA) to Frankfurt (FRA)plane plane GVA - FRA
    6h 19m
    €144–328

Lyon to Mainz by train

Calendar7Weekly Trains
Duration6h 55mAverage Duration
Ticket€140Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lyon to Mainz.ExpandLaunch map view
  • Distance: 710.4 km
  • Duration: 6h 55m

What companies run services between Lyon, France and Mainz, Germany?

You can take a train from Lyon Part Dieu to Mainz, Hauptbahnhof via Mannheim Hbf and Mannheim, Hauptbahnhof in around 6h 55m. Alternatively, Lufthansa, Airbus France, and two other airlines fly from Lyon–Saint Exupéry Airport (LYS) to Frankfurt (FRA) every 4 hours.

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