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How to get fromLyon to Mainzby train (TGV), bus, car, plane or train

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There are 8 ways to get from Lyon to Mainz by train (TGV), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Lagny-sur-Marne

    best
    1. Take the train from Lyon Part Dieu to Marne La Vallee Chessytrain train Tgv
    2. Take the train from Marne La Vallee Chessy to Mannheim Hbftrain train Tgv
    3. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    7h 36m
    €140–275
  2. Bus, train

    cheapest
    1. Take the bus from Lyon to Mannheim central bus stationbus bus FlixBus N122 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    11h 54m
    €45–79
  3. Bus

    1. Take the bus from Lyon - Perrache Bus Station to Frankfurt - Airport Bus Stationbus bus BlaBlaCar Bus
    11h 45m
    €50–70
  4. Drive 653.1 km

    1. Drive from Lyon to Mainzcar car 653.1 km
    6h 2m
    €100–144
  5. Fly Lyon–Saint Exupéry Airport to Frankfurt

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Frankfurt (FRA)plane plane LYS - FRA
    4h 38m
    €122–308
  6. Train

    1. Take the train from Lyon Part Dieu to Mannheim, Hauptbahnhoftrain train 84
    2. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    8h 40m
    €125–143
  7. Train to Geneva International Airport, fly to Frankfurt

    1. Take the train from Lyon Part Dieu to Genevetrain train
    2. Fly from Geneva International Airport (GVA) to Frankfurt (FRA)plane plane GVA - FRA
    6h 18m
    €146–345
  8. Fly Lyon–Saint Exupéry Airport to Düsseldorf International Airport, train

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Düsseldorf International Airport (DUS)plane plane LYS - DUS
    2. Take the train from Düsseldorf Hbf to Frankfurttrain train
    6h 29m
    €122–356

Lyon to Mainz by train

Calendar1Weekly Trains
Duration7h 36mAverage Duration
Ticket€140Cheapest Price
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Questions & Answers

What companies run services between Lyon, France and Mainz, Germany?

You can take a train from Lyon Part Dieu to Mainz, Römisches Theater via Marne La Vallee Chessy, Mannheim Hbf, and Mannheim, Hauptbahnhof in around 7h 36m. Alternatively, BlaBlaCar Bus operates a bus from Lyon - Perrache Bus Station to Frankfurt - Airport Bus Station twice daily. Tickets cost €50–70 and the journey takes 10h 45m.

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