There are 6 ways to get from Cheyenne to Des Moines by plane, bus (Greyhound), car, taxi, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Cheyenne Airport
best- Fly from Cheyenne Airport (CYS) to Des Moines (DSM)plane CYS - DSM
5h 50m$156–793Drive 628.4 mi
cheapest- Drive from Cheyenne to Des Moinescar 628.4 mi
9h 39m$115–166Bus
- Take the bus from Warren AFB to Denver International Airport Pickupsbus Groome Transportation - Wyoming
- Take the bus from Denver Union Station to Des Moinesbus Greyhound US0123
17h 21m$128–251Taxi to Laramie Regional Airport, fly
- Take the taxi from Cheyenne to Laramie-Airport-LARtaxi
- Fly from Laramie Regional Airport (LAR) to Des Moines (DSM)plane LAR - DSM
5h 36m$257–939Bus to Denver, fly
- Take the bus from Warren AFB to Denver International Airport Pickupsbus
- Fly from Denver (DEN) to Des Moines (DSM)plane DEN - DSM
5h 16m$210–962Bus via Omaha
- Take the bus from Warren AFB to Denver International Airport Pickupsbus
- Take the bus from Denver to Omaha, NEbus
- Take the bus from Omaha, NE to Des Moinesbus
17h 46m$243–346
Cheyenne Airport (CYS) to Des Moines (DSM) flights
Questions & Answers
The cheapest way to get from Cheyenne to Des Moines is to drive which costs $110 - $170 and takes 9h 39m.
The fastest way to get from Cheyenne to Des Moines is to bus and fly which takes 5h 16m and costs $210 - $1,000.
The distance between Cheyenne and Des Moines is 590 miles. The road distance is 632.1 miles.
The best way to get from Cheyenne to Des Moines without a car is to bus which takes 17h 21m and costs $120 - $260.
It takes approximately 5h 50m to get from Cheyenne to Des Moines, including transfers.
The best way to get from Cheyenne to Des Moines is to fly which takes 5h 50m and costs $150 - $800. Alternatively, you can bus, which costs $120 - $260 and takes 17h 21m.
Des Moines is 1h ahead of Cheyenne. It is currently 1:50 AM in Cheyenne and 2:50 AM in Des Moines.
Yes, the driving distance between Cheyenne to Des Moines is 632 miles. It takes approximately 9h 39m to drive from Cheyenne to Des Moines.
There are 120+ hotels available in Des Moines.
What companies run services between Cheyenne, WY, USA and Des Moines, IA, USA?
United Airlines flies from Cheyenne Airport (CYS) to Des Moines (DSM) 4 times a day. Alternatively, you can take a bus from Warren AFB to Des Moines via Denver International Airport Pickups, Denver Airport Station, Union Station, and Denver Union Station in around 17h 21m.
- Website
- united.com
Flights from Cheyenne Airport to Des Moines via Denver
- Ave. Duration
- 7h 27m
- When
- Every day
- Estimated price
- $130–800
Flights from Laramie Regional Airport to Des Moines via Denver
- Ave. Duration
- 6h 21m
- When
- Every day
- Estimated price
- $140–800
Flights from Denver to Des Moines
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $140–850
- Website
- southwest.com
Flights from Denver to Des Moines
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $140–850
Flights from Denver to Des Moines via St. Louis
- Ave. Duration
- 4h 7m
- When
- Saturday and Sunday
- Estimated price
- $190–1,000
- Website
- flyfrontier.com
Flights from Denver to Des Moines
- Ave. Duration
- 1h 46m
- When
- Thursday
- Estimated price
- $140–850
- Phone
- +1 970-226-5533
- Website
- groometransportation.com
Bus from Warren AFB to Denver International Airport Pickups
- Ave. Duration
- 2h 20m
- Frequency
- Every 4 hours
- Estimated price
- $50–95
- Website
- https://groometransportation.com/denver-airport
- Schedules at
- https://groometransportation.com/wyoming
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Denver Union Station to Des Moines
- Ave. Duration
- 13h 5m
- Frequency
- Once daily
- Estimated price
- $65–150
- Website
- https://www.greyhound.com/
Bus from Omaha, NE to Des Moines
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
- Phone
- +1-877-779-2999
- tony@expressarrow.com
- Website
- expressarrow.com
Bus from Denver to Omaha, NE
- Ave. Duration
- 10h 15m
- Frequency
- Once daily
- Estimated price
- $150–180
- Website
- https://expressarrow.com
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