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How to get fromBuffalo to Siesta Keyby plane, bus, bus (Flixbus, Greyhound), train, or car

Find Transport to Siesta Key

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There are 10 ways to get from Buffalo to Siesta Key by plane, bus, bus (Flixbus, Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Tampa, bus

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Tampa (TPA)plane plane BUF - TPA
    2. Take the bus from Tampa Bus Station to Sarasota Cattlemen Transfer Centerbus bus
    9h 11m
    $154–489

  2. Bus to Toronto Pearson International Airport, fly to Sarasota–Bradenton International Airport

    cheapest
    1. Take the bus from Buffalo to Mississaugabus bus
    2. Fly from Toronto Pearson International Airport (YYZ) to Sarasota–Bradenton International Airport (SRQ)plane plane YYZ - SRQ
    9h 19m
    $113–493

  3. Bus

    1. Take the bus from Buffalo to Newark Penn Stationbus bus
    2. Take the bus from Newark Penn Station to Orlando Bus Stationbus bus
    3. Take the bus from Orlando Bus Station to Sarasota Cattlemen Transfer Centerbus bus
    35h 21m
    $260–407

  4. Train, bus

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Winter Park Amtrak Stationtrain train
    3. Take the bus from Orlando Bus Station to Sarasota Cattlemen Transfer Centerbus bus
    37h 33m
    $887–1,383

  5. Drive  1,278.4 mi

    1. Drive from Buffalo to Siesta Keycar car 1,278.4 mi
    21h 58m
    $226–327

  6. Fly Buffalo Niagara International Airport to Orlando, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Orlando (MCO)plane plane BUF - MCO
    2. Take the bus from Orlando to Sarasota Cattlemen Transfer Centerbus bus
    11h 15m
    $210–426

  7. Line 40 bus to Niagara Falls International Airport, fly to Punta Gorda Airport, line 09 bus, line 17 bus

    1. Take the bus from Niagara Street & West Mohawk Street to 3rd Street & Niagara Streetbus bus
    2. Fly from Niagara Falls International Airport (IAG) to Punta Gorda Airport (PGD)plane plane IAG - PGD
    3. Take the bus from North Port City Hall And Park And Ride to Venice Train Depotbus bus
    4. Take the bus from Venice Train Depot to Siesta Dr @ Mall Sidebus bus
    9h 54m
    $151–541

  8. Fly Buffalo Niagara International Airport to Ft. Myers, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Ft. Myers (RSW)plane plane BUF - RSW
    2. Take the bus from Fort Myers Bus Stop to Sarasota Cattlemen Transfer Centerbus bus
    10h 58m
    $138–626

  9. Bus to Toronto Pearson International Airport, fly to Tampa, bus

    1. Take the bus from Buffalo to Mississaugabus bus
    2. Fly from Toronto Pearson International Airport (YYZ) to Tampa (TPA)plane plane YYZ - TPA
    3. Take the bus from Tampa Bus Station to Sarasota Cattlemen Transfer Centerbus bus
    12h 54m
    $158–1,276

  10. Bus, train

    1. Take the bus from Buffalo, Ny to Pittsburgh, Pabus bus 530
    2. Take the train from Pittsburgh Amtrak Station to Winter Park Amtrak Stationtrain train
    3. Take the bus from Orlando Bus Station to Sarasota Cattlemen Transfer Centerbus bus
    42h 51m
    $745–1,374

Buffalo to Siesta Key by bus

Calendar4Weekly Buses
Duration35h 21mAverage Duration
Ticket$260Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Buffalo to Siesta Key.ExpandLaunch map view
  • Distance: 1,141.9 mi
  • Duration: 9h 11m

What companies run services between Buffalo, NY, USA and Siesta Key, FL, USA?

You can take a bus from Buffalo to Ocean Blvd @ Avenida Madera via Newark Penn Station, Orlando Bus Station, Sarasota Cattlemen Transfer Center, and Cattlemen Transit Station in around 35h 21m.

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Train operators
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