Rome2Rio

How to get fromBuffalo to Mobileby plane, bus (Greyhound), train (Amtrak), car, or bus

Find Transport to Mobile

See all options

There are 9 ways to get from Buffalo to Mobile by plane, bus (Greyhound), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Mobile Regional Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Mobile Regional Airport (MOB)plane plane BUF - MOB
    8h 37m
    $166–828

  2. Bus to Rochester, fly to Mobile Regional Airport

    cheapest
    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Mobile Regional Airport (MOB)plane plane ROC - MOB
    10h 6m
    $148–647

  3. Bus (Greyhound)

    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Toledo Bus Stopbus bus
    3. Take the bus from Toledo Bus Stop to Montgomery Intermodal Centerbus bus
    4. Take the bus from Montgomery Intermodal Center to Mobile Bus Stationbus bus
    29h 49m
    $219–434

  4. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train
    36h 15m
    $459–1,093

  5. Drive 1,126.8 mi

    1. Drive from Buffalo to Mobilecar car 1,126.8 mi
    19h 57m
    $206–297

  6. Fly Buffalo Niagara International Airport to Gulfport-Biloxi Regional Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Gulfport-Biloxi Regional Airport (GPT)plane plane BUF - GPT
    2. Take the bus from Gulfport to Mobilebus bus
    7h 53m
    $268–1,059

  7. Fly Buffalo Niagara International Airport to Destin–Fort Walton Beach Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Destin–Fort Walton Beach Airport (VPS)plane plane BUF - VPS
    2. Take the bus from McDonald's - Crestview to Love's Travel Stop - Loxleybus bus
    8h 39m
    $296–1,088

  8. Fly Buffalo Niagara International Airport to Pensacola International Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Pensacola International Airport (PNS)plane plane BUF - PNS
    2. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    9h 47m
    $176–848

  9. Bus via Atlanta

    1. Take the bus from Buffalo, NY to Mansfield, OHbus bus
    2. Take the bus from Mansfield Bus Stop to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Mobile Bus Stationbus bus
    34h 9m
    $204–421

Buffalo to Mobile by bus (Greyhound)

Calendar7Weekly Buses
Duration29h 49mAverage Duration
Ticket$219Cheapest Price
See schedules

Questions & Answers

What companies run services between Buffalo, NY, USA and Mobile, AL, USA?

Delta, United Airlines, and American Airlines fly from Buffalo Niagara International Airport (BUF) to Mobile Regional Airport (MOB) every 4 hours. Alternatively, you can take a bus from Buffalo to Water NB at St Louis St via Cleveland Bus Station, Toledo Bus Stop, Montgomery Intermodal Center, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 29h 49m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Trips from Buffalo

Trips to Mobile

Popular routes