Travel options for:
Boston to St. Louis
  • Fly

    $155 - $484
    1. Boston

      15 min - every 15 minutes

      $2 - $23

    2. Boston (BOS)

      3 h 15 min - non-stop

      $150 - $460

    3. St. Louis (STL)

      30 min - every 20 minutes

      $2

  • Bus

    $110 - $304
    1. Boston, MA

      4 h 20 min - hourly

      $10 - $65

    2. New York, NY

      22 h 45 min - once daily

      $100 - $240

  • Train

    $186 - $519
    1. Boston South Station Amtrak

      21 h 55 min - once daily

      $130 - $390

    2. Chicago Union Station Amtrak

      5 h 30 min - 3 times a day

      $50 - $130

  • Drive

    $110 - $170
    1. Boston

      19 h 47 min - 1184.8 miles

      $110 - $170

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From South Station Silver Line - Outbound bus to Boston airport, fly to St. Louis airport, then train to St. Louis. 5 h 10 min $244. From Boston, MA bus to New York, NY then bus to St Louis, MO. 28 h 5 min $201. From Boston South Station Amtrak train to Chicago Union Station Amtrak then train to St. Louis Gateway Station Amtrak. 28 h 25 min $376. From Boston drive to St. Louis. 19 h 47 min $141.