There are 6 ways to get from Boston to St. Louis by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from Boston  •  4h 43m

  1. Fly from Boston (BOS) to St. Louis (STL) BOS - STL

$80 - $383

5 alternative options

Bus to Manchester, fly  •  7h 24m

  1. Take the bus from Boston South Buses to North Londonderry, NH - exit 5
  2. Fly from Manchester (MHT) to St. Louis (STL) MHT - STL

$126 - $452

Bus to Hartford, fly  •  7h 24m

  1. Take the bus from Boston South Buses to Hartford, Ct
  2. Fly from Hartford (BDL) to St. Louis (STL) BDL - STL

$131 - $631

Train  •  28h 30m

  1. Take the train from Boston South Station to Chicago Union Station Lake Shore Limited
  2. Take the train from Chicago Union Station to St. Louis Gateway Station Lincoln Service / ...

$143 - $203

Bus  •  30h 20m

  1. Take the bus from South Station, Boston, MA to Port Authority Bus Terminal, New York, NY Peter Pan
  2. Take the bus from New York, Ny to Greyhound Bus Station St. Louis 1683 / ...

$135 - $198

Drive  •  19h 49m

  1. Drive from Boston to St. Louis 1184.8 miles

$110 - $170

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Questions & Answers

The cheapest way to get from Boston to St. Louis is to drive which costs $110 - $170 and takes 19h 49m.

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The quickest way to get from Boston to St. Louis is to fly which costs $75 - $390 and takes 4h 43m.

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No, there is no direct bus from Boston station to St. Louis station. However, there are services departing from South Station, Boston, MA and arriving at Greyhound Bus Station St. Louis via New York, Ny. The journey, including transfers, takes approximately 30h 20m.

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No, there is no direct train from Boston station to St. Louis station. However, there are services departing from Boston South Station and arriving at St. Louis Gateway Station via Chicago Union Station. The journey, including transfers, takes approximately 28h 30m.

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The distance between Boston and St. Louis is 1042 miles. The road distance is 1184.8 miles.

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The best way to get from Boston to St. Louis without a car is to train which takes 28h 30m and costs $140 - $210.

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It takes approximately 4h 43m to get from Boston to St. Louis, including transfers.

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Boston to St. Louis bus services, operated by Peter Pan Bus Lines, depart from South Station, Boston, MA.

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Boston to St. Louis train services, operated by Amtrak, depart from Boston South Station.

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The best way to get from Boston to St. Louis is to fly which takes 4h 43m and costs $75 - $390. Alternatively, you can train, which costs $140 - $210 and takes 28h 30m, you could also bus, which costs $130 - $200 and takes 30h 20m.

Mode details

Map of how to get from Boston to St. Louis.
Launch map view
  • Distance: 1041.7 miles
  • Duration: 4h 43m

What companies run services between Boston, MA, USA and St. Louis, MO, USA?

Southwest Airlines, Delta and two other airlines fly from Boston to St. Louis hourly. Alternatively, you can take a train from Boston to St. Louis via Chicago Union Station in around 28h 30m.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Boston to St. Louis
Ave. Duration
3h 4m
When
Every day
Estimated price
$90 - $380
Flights from Boston to St. Louis via Columbus
Ave. Duration
4h 30m
When
Monday to Friday
Estimated price
$90 - $380
Flights from Boston to St. Louis via Baltimore
Ave. Duration
4h 48m
When
Saturday and Sunday
Estimated price
$90 - $390
Flights from Boston to St. Louis via Nashville
Ave. Duration
4h 50m
When
Sunday
Estimated price
$95 - $400
Flights from Boston to St. Louis via Chicago Midway
Ave. Duration
5h
When
Sunday
Estimated price
$90 - $390
Flights from Manchester to St. Louis via Baltimore
Ave. Duration
5h 23m
When
Every day
Estimated price
$90 - $400
Flights from Manchester to St. Louis via Chicago Midway
Ave. Duration
5h 56m
When
Every day
Estimated price
$90 - $400
Flights from Manchester to St. Louis via Orlando
Ave. Duration
6h 50m
When
Sunday
Estimated price
$110 - $490
Flights from Hartford to St. Louis
Ave. Duration
2h 43m
When
Every day
Estimated price
$130 - $600
Flights from Hartford to St. Louis via Baltimore
Ave. Duration
4h 35m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$130 - $600
Flights from Hartford to St. Louis via Chicago Midway
Ave. Duration
4h 42m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$130 - $600
American Airlines
Website
aa.com
Flights from Boston to St. Louis via Chicago O'Hare
Ave. Duration
4h 53m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$75 - $370
Flights from Manchester to St. Louis via Chicago O'Hare
Ave. Duration
5h 3m
When
Every day
Estimated price
$75 - $380
Flights from Manchester to St. Louis via Philadelphia
Ave. Duration
5h 51m
When
Every day
Estimated price
$75 - $380
Flights from Manchester to St. Louis via Charlotte
Ave. Duration
6h 45m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$80 - $390
Flights from Manchester to St. Louis via Reagan Washington
Ave. Duration
6h 46m
When
Every day
Estimated price
$80 - $380
Flights from Hartford to St. Louis via Reagan Washington
Ave. Duration
4h 44m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$110 - $600
Flights from Hartford to St. Louis via Charlotte
Ave. Duration
4h 56m
When
Every day
Estimated price
$120 - $600
Flights from Hartford to St. Louis via Chicago O'Hare
Ave. Duration
4h 57m
When
Every day
Estimated price
$110 - $600
Delta
Website
delta.com
Flights from Boston to St. Louis via Detroit
Ave. Duration
4h 51m
When
Monday to Friday
Estimated price
$180 - $600
Flights from Manchester to St. Louis via Detroit
Ave. Duration
5h 31m
When
Every day
Estimated price
$190 - $600
Flights from Manchester to St. Louis via Atlanta
Ave. Duration
6h 33m
When
Every day
Estimated price
$230 - $800
Flights from Manchester to St. Louis via New York La Guardia
Ave. Duration
6h 52m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$190 - $600
Flights from Hartford to St. Louis via Detroit
Ave. Duration
4h 41m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$270 - $850
United Airlines
Website
united.com
Flights from Boston to St. Louis via Washington Dulles
Ave. Duration
4h 53m
When
Every day
Estimated price
$110 - $480
Flights from Manchester to St. Louis via Washington Dulles
Ave. Duration
5h 10m
When
Every day
Estimated price
$110 - $490
Flights from Hartford to St. Louis via Washington Dulles
Ave. Duration
4h 52m
When
Every day
Estimated price
$170 - $750
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Boston South Station to Chicago Union Station
Ave. Duration
22h
Frequency
Once daily
Estimated price
$100 - $150
Website
amtrak.com
Coach Seat
$100 - $150
Premium
$330 - $460
Flexi Coach Seat
$200 - $310
Business Seat
$220 - $310
Train from Chicago Union Station to St. Louis Gateway Station
Ave. Duration
5h 30m
Frequency
5 times a day
Estimated price
$40 - $60
Website
amtrak.com
Coach Seat
$40 - $60
Premium
$210 - $300
Flexi Coach Seat
$75 - $110
Business Seat
$75 - $110
Bus operators
Boston Express
Phone
1800-639-8080
Email
contact@bostonexpressbus.com
Website
bostonexpressbus.com
Bus from Boston South Buses to North Londonderry, NH - exit 5
Ave. Duration
55 min
Frequency
Hourly
Estimated price
$12 - $19
Schedules at
bostonexpressbus.com
Book at
webstore.bostonexpressbus.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Boston South Buses to Hartford, Ct
Ave. Duration
1h 50m
Frequency
Every 3 hours
Estimated price
$17 - $24
Website
greyhound.com
Economy
$17 - $24
Flexible
$35 - $50
Bus from New York, Ny to Greyhound Bus Station St. Louis
Ave. Duration
25h 5m
Frequency
5 times a day
Estimated price
$100 - $150
Website
greyhound.com
Economy
$100 - $150
Flexible
$150 - $220
Peter Pan Bus Lines
Phone
1-800-343-9999
Website
peterpanbus.com
Bus from South Station, Boston, MA to Port Authority Bus Terminal, New York, NY
Ave. Duration
4h 15m
Frequency
Every 4 hours
Estimated price
$35 - $50
Website
peterpanbus.com

Want to know more about travelling around United States

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More Questions & Answers

The quickest flight from Boston Airport to St. Louis Airport is the direct flight which takes 3h.

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Boston to St. Louis bus services, operated by Greyhound USA, arrive at Greyhound Bus Station St. Louis.

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St. Louis is 1h behind Boston. It is currently 1:52 AM in Boston and 12:52 AM in St. Louis.

Boston to St. Louis train services, operated by Amtrak, arrive at St. Louis Gateway Station.

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Yes, the driving distance between Boston to St. Louis is 1185 miles. It takes approximately 19h 49m to drive from Boston to St. Louis.

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Delta, United Airlines, American Airlines and Southwest Airlines offer flights from Boston Airport to St. Louis Airport.

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Book your Boston to St. Louis train tickets online with Omio and Omio.

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There are 310+ hotels available in St. Louis. Prices start at $100 USD per night.

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The best way to get from Boston to Boston Airport is to bus which takes 0 min and costs $1 - $11.

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