There are 5 ways to get from Boston to St. Louis by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from Boston  •  5 h 3 min

  1. Fly from Boston (BOS) to St. Louis (STL) BOS - STL

$155 - $473

Cheapest option

Bus  •  29 h 8 min

  1. Take the bus from Boston, MA - South Station to New York City, NY - Port Authority Bus Terminal Boston / ...
  2. Take the bus from New York, Ny to St Louis, Mo 1683 / ...

$117 - $311

3 alternative options

Bus to Hartford, fly  •  7 h 21 min

  1. Take the bus from Boston, Ma to Hartford, Ct
  2. Fly from Hartford (BDL) to St. Louis (STL) BDL - STL

$180 - $413

Train  •  27 h 50 min

  1. Take the train from Boston South Station to Chicago Union Station Lake Shore Limited
  2. Take the train from Chicago Union Station to St. Louis Gateway Station Lincoln Service / ...

$186 - $519

Drive  •  19 h 47 min

  1. Drive from Boston to St. Louis 1184.8 miles

$110 - $170

Questions & Answers

No, there is no direct bus from Boston station to St. Louis. However, there are services departing from Boston, MA - South Station and arriving at St Louis, Mo via New York, Ny. The journey, including transfers, takes approximately 29 h 8 min.

More details

No, there is no direct train from Boston station to St. Louis station. However, there are services departing from Boston South Station and arriving at St. Louis Gateway Station via Chicago Union Station. The journey, including transfers, takes approximately 27 h 50 min.

More details

The distance between Boston and St. Louis is 1042 miles. The road distance is 1184.8 miles.

Get driving directions

The best way to get from Boston to St. Louis without a car is to train which takes 27 h 50 min and costs .

More details

It takes approximately 5 h 3 min to get from Boston to St. Louis, including transfers.

More details

Boston to St. Louis bus services, operated by Peter Pan Bus Lines, arrive at Boston, MA - South Station.

More details

Boston to St. Louis train services, operated by Amtrak, arrive at Boston South Station.

More details

The best way to get from Boston to St. Louis is to fly which takes 5 h 3 min and costs . Alternatively, you can train, which costs and takes 27 h 50 min, you could also bus, which costs and takes 29 h 8 min.

Mode details

The quickest flight from Boston Airport to St. Louis Airport is the direct flight which takes 3 h.

Search flights

Boston to St. Louis bus services, operated by Greyhound USA, arrive at St Louis, Mo station.

More details

Map of how to get from Boston to St. Louis.
Launch map view
  • Distance: 1041.7 miles
  • Duration: 5 h 3 min

What companies run services between Boston, MA, USA and St. Louis, MO, USA?

Southwest Airlines, Delta and two other airlines fly from Boston to St. Louis hourly. Alternatively, you can take a train from Boston to St. Louis via Chicago Union Station in around 27 h 50 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Boston to St. Louis
Ave. Duration
3 h 4 min
When
Every day
Estimated price
$440 - $1,100
Flights from Boston to St. Louis via Baltimore
Ave. Duration
4 h 35 min
When
Saturday
Estimated price
$440 - $1,100
Flights from Boston to St. Louis via Columbus
Ave. Duration
4 h 45 min
When
Sunday
Estimated price
$440 - $1,100
Flights from Boston to St. Louis via Chicago Midway
Ave. Duration
4 h 51 min
When
Monday to Saturday
Estimated price
$440 - $1,100
Flights from Boston to St. Louis via Milwaukee
Ave. Duration
4 h 55 min
When
Sunday
Estimated price
$440 - $1,100
Flights from Hartford to St. Louis
Ave. Duration
2 h 40 min
When
Every day
Estimated price
$390 - $850
Flights from Hartford to St. Louis via Baltimore
Ave. Duration
4 h 40 min
When
Monday to Saturday
Estimated price
$390 - $850
Flights from Hartford to St. Louis via Chicago Midway
Ave. Duration
4 h 50 min
When
Monday to Friday
Estimated price
$390 - $850
Delta
Website
delta.com
Flights from Boston to St. Louis via Detroit
Ave. Duration
4 h 50 min
When
Every day
Estimated price
$250 - $950
Flights from Hartford to St. Louis via Detroit
Ave. Duration
4 h 45 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$300 - $850
United Airlines
Website
united.com
Flights from Boston to St. Louis via Chicago O'Hare
Ave. Duration
4 h 53 min
When
Every day
Estimated price
$350 - $1,100
Flights from Hartford to St. Louis via Washington Dulles
Ave. Duration
4 h 30 min
When
Saturday
Estimated price
$340 - $1,200
Flights from Hartford to St. Louis via Chicago O'Hare
Ave. Duration
4 h 53 min
When
Every day
Estimated price
$340 - $1,200
American Airlines
Website
aa.com
Flights from Boston to St. Louis via Chicago O'Hare
Ave. Duration
5 h
When
Monday to Friday
Estimated price
$350 - $800
Flights from Hartford to St. Louis via Chicago O'Hare
Ave. Duration
4 h 44 min
When
Every day
Estimated price
$300 - $1,000
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Boston South Station to Chicago Union Station
Ave. Duration
21 h 20 min
Frequency
Once daily
Estimated price
$130 - $390
Website
amtrak.com
Coach Seat
$130 - $200
Flexi Coach Seat
$240 - $340
Business Coach Seat
$280 - $390
Room
$500 - $750
Train from Chicago Union Station to St. Louis Gateway Station
Ave. Duration
5 h 30 min
Frequency
Every 4 hours
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$90 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Boston, Ma to Hartford, Ct
Ave. Duration
1 h 50 min
Frequency
Every 20 minutes
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $24
Flexible
$28 - $40
Bus from Boston, Ma to New York, Ny
Ave. Duration
6 h 55 min
Frequency
Every 10 minutes
Estimated price
$26 - $65
Website
greyhound.com
Economy
$26 - $40
Flexible
$45 - $65
Bus from New York, Ny to St Louis, Mo
Ave. Duration
25 h 5 min
Frequency
Every 30 minutes
Estimated price
$95 - $250
Website
greyhound.com
Economy
$95 - $160
Flexible
$190 - $250
Peter Pan Bus Lines
Phone
1-800-343-9999
Website
peterpanbus.com
Bus from Boston, MA - South Station to New York City, NY - Port Authority Bus Terminal
Ave. Duration
3 h 45 min
Frequency
Hourly
Estimated price
$21 - $40
Website
peterpanbus.com

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

St. Louis is 1 h behind Boston. It is currently 9:02 AM in Boston and 8:02 AM in St. Louis.

Boston to St. Louis train services, operated by Amtrak, arrive at St. Louis Gateway Station.

More details

Yes, the driving distance between Boston to St. Louis is 1185 miles. It takes approximately 19 h 47 min to drive from Boston to St. Louis.

Get driving directions

American Airlines, United Airlines, Delta and Southwest Airlines offer flights from Boston Airport to St. Louis Airport.

Search flights

Book your Boston to St. Louis train tickets online with Rome2rio.

Search and book

There are 193+ hotels available in St. Louis. Prices start at $70 USD per night.

More details

The best way to get from Boston to Boston Airport is to bus which takes 15 min and costs .

More details