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How to get fromBoston to St. Louisby plane, bus (Greyhound, Flixbus), train (Amtrak) or car

Find Transport to St. Louis

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There are 4 ways to get from Boston to St. Louis by plane, bus (Greyhound, Flixbus), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Boston Logan Airport (BOS) to Lambert–St. Louis International Airport (STL)plane plane BOS - STL
    3h 58m
    $247–594
  2. Bus

    cheapest
    1. Take the bus from Boston to Newark Penn Stationbus bus Greyhound US0235 / ...
    2. Take the bus from Newark Penn Station to St Louis Bus Stationbus bus Greyhound US0421
    28h
    $135–392
  3. Train (Amtrak)

    1. Take the train from Boston to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    28h 8m
    $145–888
  4. Drive 1,150.4 mi

    1. Drive from Boston to St. Louiscar car 1,150.4 mi
    20h 20m
    $210–304

Boston to St. Louis by bus

Calendar7Weekly Buses
Duration28hAverage Duration
Ticket$135Cheapest Price
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Questions & Answers

What companies run services between Boston, MA, USA and St. Louis, MO, USA?

American Airlines, Southwest Airlines, and Delta fly from Boston Logan Airport (BOS) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from Boston to St Louis Bus Station via Newark Penn Station in around 28h.

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Need to know: Greyhound

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