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There are 3 ways to get from Columbus to St. Louis by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  3h 11m

  1. Fly from Columbus (CMH) to St. Louis (STL) CMH - STL

$116 - $278

Cheapest option

Bus  •  9h 10m

  1. Take the bus from Columbus, Oh to St Louis, Mo 1683 / ...

$40 - $110

1 alternative option

Drive  •  7h 3m

  1. Drive from Columbus to St. Louis 419 miles

$40 - $60

Questions & Answers

The cheapest way to get from Columbus to St. Louis is to drive which costs $40 - $60 and takes 7h 3m.

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The quickest way to get from Columbus to St. Louis is to fly which costs $110 - $280 and takes 3h 11m.

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Yes, there is a direct bus departing from Columbus, Oh and arriving at St Louis, Mo. Services depart five times a day, and operate every day. The journey takes approximately 9h 10m.

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The distance between Columbus and St. Louis is 398 miles. The road distance is 419 miles.

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The best way to get from Columbus to St. Louis without a car is to bus which takes 9h 10m and costs $40 - $110.

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It takes approximately 3h 11m to get from Columbus to St. Louis, including transfers.

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Columbus to St. Louis bus services, operated by Greyhound USA, depart from Columbus, Oh station.

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The best way to get from Columbus to St. Louis is to fly which takes 3h 11m and costs $110 - $280. Alternatively, you can bus, which costs $40 - $110 and takes 9h 10m.

Mode details

The quickest flight from Columbus Airport to St. Louis Airport is the direct flight which takes 1h 25m.

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Columbus to St. Louis bus services, operated by Greyhound USA, arrive at St Louis, Mo station.

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Map of how to get from Columbus to St. Louis.
Launch map view
  • Distance: 398 miles
  • Duration: 3h 11m

What companies run services between Columbus, OH, USA and St. Louis, MO, USA?

Southwest Airlines and American Airlines fly from Columbus to St. Louis 4 times a day. Alternatively, Greyhound USA operates a bus from Columbus to St. Louis 5 times a day. Tickets cost $40 - $110 and the journey takes 9h 10m.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Columbus to St. Louis
Ave. Duration
1h 30m
When
Every day
Estimated price
$270 - $550
Flights from Columbus to St. Louis via Nashville
Ave. Duration
3h 35m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$270 - $550
Flights from Columbus to St. Louis via Chicago Midway
Ave. Duration
3h 25m
When
Saturday
Estimated price
$270 - $550
American Airlines
Website
aa.com
Flights from Columbus to St. Louis via Chicago O'Hare
Ave. Duration
3h 40m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$130 - $550
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Columbus, Oh to St Louis, Mo
Ave. Duration
9h 10m
Frequency
5 times a day
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$80 - $110

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

St. Louis is 1h behind Columbus. It is currently 5:09 AM in Columbus and 4:09 AM in St. Louis.

Yes, the driving distance between Columbus to St. Louis is 419 miles. It takes approximately 7h 3m to drive from Columbus to St. Louis.

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American Airlines and Southwest Airlines offer flights from Columbus Airport to St. Louis Airport.

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Book your Columbus to St. Louis bus tickets online with Greyhound.

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There are 200+ hotels available in St. Louis. Prices start at $65 USD per night.

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The best way to get from Columbus to Columbus Airport is to bus which takes 10m and costs $3 - $5.

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