There are 3 ways to get from Columbus to St. Louis by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  3 h 6 min

  1. Fly from Columbus (CMH) to St. Louis (STL) CMH - STL

$116 - $278

Cheapest option

Bus  •  9 h 10 min

  1. Take the bus from Columbus, Oh to St Louis, Mo 1683 / ...

$40 - $110

1 alternative option

Drive  •  7 h 3 min

  1. Drive from Columbus to St. Louis 419 miles

$40 - $60

Questions & Answers

The cheapest way to get from Columbus to St. Louis is to drive which costs $40 - $60 and takes 7 h 3 min.

More details

The quickest way to get from Columbus to St. Louis is to fly which costs $110 - $280 and takes 3 h 6 min.

More details

The distance between Columbus and St. Louis is 398 miles. The road distance is 419 miles.

Get driving directions

It takes approximately 3 h 6 min to get from Columbus to St. Louis, including transfers.

More details

Yes, there is a direct bus departing from Columbus, Oh and arriving at St Louis, Mo. Services depart hourly, and operate every day. The journey takes approximately 9 h 10 min.

More details

What companies run services between Columbus, OH, USA and St. Louis, MO, USA?

Southwest Airlines and American Airlines fly from Columbus to St. Louis 4 times a day. Alternatively, Greyhound USA operates a bus from Columbus to St. Louis hourly. Tickets cost $40 - $110 and the journey takes 9 h 10 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Columbus to St. Louis
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$270 - $550
Flights from Columbus to St. Louis via Chicago Midway
Ave. Duration
3 h 20 min
When
Monday to Saturday
Estimated price
$270 - $550
American Airlines
Website
aa.com
Flights from Columbus to St. Louis via Chicago O'Hare
Ave. Duration
3 h 26 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$130 - $550
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Columbus, Oh to St Louis, Mo
Ave. Duration
9 h 10 min
Frequency
Hourly
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$80 - $110

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