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How to get fromAppleton to Louisvilleby plane, bus (Flixbus, Greyhound, Amtrak), bus, train, car or bus (Flixbus, Amtrak)

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There are 7 ways to get from Appleton to Louisville by plane, bus (Flixbus, Greyhound, Amtrak), bus, train, car, or bus (Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Appleton International Airport to Louisville International Airport

    best
    1. Fly from Appleton International Airport (ATW) to Louisville International Airport (SDF)plane plane ATW - SDF
    5h 1m
    $94–495

  2. Fly Appleton International Airport to Blue Grass Airport, drive

    cheapest
    1. Fly from Appleton International Airport (ATW) to Blue Grass Airport (LEX)plane plane ATW - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    5h 6m
    $81–381

  3. Bus via Indianapolis

    1. Take the bus from Appleton Transit Center to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    12h
    $83–142

  4. Bus, train

    1. Take the bus from Appleton Amtrak Station to Milwaukeebus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    14h 11m
    $94–156

  5. Drive 483.2 mi

    1. Drive from Appleton to Louisvillecar car 483.2 mi
    8h 27m
    $89–128

  6. Fly Green Bay to Louisville International Airport

    1. Fly from Green Bay (GRB) to Louisville International Airport (SDF)plane plane GRB - SDF
    6h 35m
    $112–525

  7. Bus

    1. Take the bus from Appleton Transit Center to Chicago Bus Stationbus bus FlixBus 2550
    2. Take the bus from Chicago Union Station to Louisville, KYbus bus Chicago
    12h 39m
    $81–102

Appleton to Louisville by bus

Calendar5Weekly Buses
Duration12hAverage Duration
Ticket$83Cheapest Price
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Questions & Answers

What companies run services between Appleton, WI, USA and Louisville, KY, USA?

American Airlines, Delta, and United Airlines fly from Appleton International Airport (ATW) to Louisville International Airport (SDF) every 3 hours. Alternatively, you can take a bus from Appleton Transit Center to Louisville, KY via Chicago Bus Station and Indianapolis Union Station in around 12h.

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