There are 4 ways to get from Appleton to La Crosse by bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Appleton Valley Transit to La Crosse Grand River Stationbus Green Bay
4h 15m$34–39Drive 167.6 mi
cheapest- Drive from Appleton to La Crossecar 167.6 mi
3h 30m$31–45Fly from Appleton International Airport
- Fly from Appleton International Airport (ATW) to La Crosse (LSE)plane ATW - LSE
4h 12m$82–365Fly from Green Bay
- Fly from Green Bay (GRB) to La Crosse (LSE)plane GRB - LSE
6h 12m$100–385
Appleton to La Crosse by bus
Questions & Answers
The cheapest way to get from Appleton to La Crosse is to bus which costs $34 - $39 and takes 4h 15m.
The fastest way to get from Appleton to La Crosse is to drive which takes 3h 30m and costs $30 - $45.
Yes, there is a direct bus departing from Appleton Valley Transit and arriving at La Crosse Grand River Station station. Services depart once daily, and operate every day. The journey takes approximately 4h 15m.
The distance between Appleton and La Crosse is 184 miles. The road distance is 168.6 miles.
The best way to get from Appleton to La Crosse without a car is to bus which takes 4h 15m and costs $34 - $39.
The bus from Appleton Valley Transit to La Crosse Grand River Station takes 4h 15m including transfers and departs once daily.
Appleton to La Crosse bus services, operated by Lamers Bus Lines, depart from Appleton Valley Transit station.
The best way to get from Appleton to La Crosse is to bus which takes 4h 15m and costs $34 - $39. Alternatively, you can fly, which costs $80 - $370 and takes 4h 12m.
Appleton to La Crosse bus services, operated by Lamers Bus Lines, arrive at La Crosse Grand River Station.
Yes, the driving distance between Appleton to La Crosse is 169 miles. It takes approximately 3h 30m to drive from Appleton to La Crosse.
What companies run services between Appleton, WI, USA and La Crosse, WI, USA?
Lamers Bus Lines operates a bus from Appleton Valley Transit to La Crosse Grand River Station once daily. Tickets cost $34–39 and the journey takes 4h 15m. Alternatively, American Airlines and United Airlines fly from Appleton International Airport (ATW) to La Crosse (LSE) 3 times a day.
- Website
- aa.com
Flights from Appleton International Airport to La Crosse via Chicago O'Hare
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- $45–320
Flights from Green Bay to La Crosse via Chicago O'Hare
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $45–320
- Phone
- 920 496 3600
- Website
- golamers.com
Bus from Appleton Valley Transit to La Crosse Grand River Station
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- $34–39
- Schedules at
- golamers.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 52+ hotels available in La Crosse.

