There are 5 ways to get from Appleton to La Crosse by bus, train, car, plane, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Oshkosh to Milwaukeebus Lab 211
- Take the train from Milwaukee to La Crosse Amtrak Stationtrain Empire Builder / ...
6h 29m$168–250Drive 166.7 mi
cheapest- Drive from Appleton to La Crossecar 166.7 mi
3h 39m$31–44Bus
- Take the bus from Oshkosh to Milwaukeebus Lab 211
- Take the bus from Milwaukee to La Crossebus Jefferson Lines 966
8h 6m$101–140Fly from Appleton International Airport
- Fly from Appleton International Airport (ATW) to La Crosse (LSE)plane ATW - LSE
4h 13m$83–380Taxi to Green Bay, fly
- Take the taxi from Appleton to Green Bay (GRB)taxi
- Fly from Green Bay (GRB) to La Crosse (LSE)plane GRB - LSE
4h 51m$168–480
Appleton International Airport (ATW) to La Crosse (LSE) flights
Comparing Your Travel Options
The cheapest way to get from Appleton to La Crosse is to drive which costs $30 - $45 and takes 3h 39m.
The fastest way to get from Appleton to La Crosse is to drive which takes 3h 39m and costs $30 - $45.
No, there is no direct bus from Appleton to La Crosse. However, there are services departing from Prospect and Walnut and arriving at La Crosse via Oshkosh and Milwaukee. The journey, including transfers, takes approximately 8h 6m.
The distance between Appleton and La Crosse is 298 miles. The road distance is 167.7 miles.
The best way to get from Appleton to La Crosse without a car is to bus and train which takes 6h 29m and costs $160 - $250.
It takes approximately 6h 29m to get from Appleton to La Crosse, including transfers.
Appleton to La Crosse bus services, operated by Lamers Bus Lines, depart from Oshkosh station.
The best way to get from Appleton to La Crosse is to bus which takes 8h 6m and costs $100 - $140. Alternatively, you can fly, which costs $80 - $380 and takes 4h 13m.
Appleton to La Crosse bus services, operated by Lamers Bus Lines, arrive at Milwaukee station.
Yes, the driving distance between Appleton to La Crosse is 168 miles. It takes approximately 3h 39m to drive from Appleton to La Crosse.
What companies run services between Appleton, WI, USA and La Crosse, WI, USA?
You can take a bus from Prospect and Walnut to La Crosse via Church @ Doty - Neenah Transit Center, Oshkosh, and Milwaukee in around 8h 6m. Alternatively, American Airlines and United Airlines fly from Appleton International Airport (ATW) to La Crosse (LSE) every 4 hours.
- Website
- aa.com
Flights from Appleton International Airport to La Crosse via Chicago O'Hare
- Ave. Duration
- 5h 37m
- When
- Every day
- Estimated price
- $50–340
Flights from Green Bay to La Crosse via Chicago O'Hare
- Ave. Duration
- 5h 29m
- When
- Every day
- Estimated price
- $50–340
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Milwaukee to La Crosse Amtrak Station
- Ave. Duration
- 3h 19m
- Frequency
- 3 times a day
- Estimated price
- $100–170
- Website
- Amtrak
- Phone
- 920 496 3600
- Website
- example.com
Bus from Oshkosh to Milwaukee
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $20–23
- Schedules at
- golamers.com
Bus from Oshkosh to Milwaukee
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $20–23
- Schedules at
- golamers.com
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Milwaukee to La Crosse
- Ave. Duration
- 3h 40m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
- Ave. Duration
- 41 min
- Estimated price
- $95–120
Able Taxi and Tours
- Phone
- +1 920-265-7760
- Website
- abletaxiandtours.com
Appleton Yellow Taxi
- Phone
- +1 920-733-4444
- Website
- appletonyellowtaxi.com
Fox Valley Cab
- Phone
- +1 920-734-4545
- Website
- facebook.com
Want to know more about travelling around United States
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Booking & Getting There
There are 38+ hotels available in La Crosse.








