The average train between Zwickau and Mainz takes 5h 53m and the fastest train takes 5h 20m. There is a train service every few hours from Zwickau to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Zwickau and Mainz. The earliest departure is at 5:01 AM in the morning, and the last departure from Zwickau is at 10:34 PM which arrives into Mainz at 9:22 AM. All services require a transfer at Leipzig Hbf and take an average of 5h 53m. The schedules shown below are for the next available departures.


5h 38m • 2 changes


5h 31m • 2 changes


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5h 43m • 2 changes


5h 31m • 2 changes


5h 38m • 2 changes


5h 31m • 2 changes


5h 43m • 2 changes


5h 31m • 2 changes


5h 38m • 2 changes


5h 31m • 2 changes
Want to know about travelling from Zwickau to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Zwickau to Mainz. However, there are services departing from Zwickau station and arriving at Mainz station via Leipzig Hbf. The journey, including transfers, takes approximately 5h 53m.
Zwickau to Mainz train services, operated by Deutsche Bahn Regio (DB Regional), depart from Zwickau, Hauptbahnhof station.
Zwickau to Mainz train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Frankfurt station.
The distance between Zwickau and Mainz is 309.8 km. The road distance is 494 km.
You can take a train from Zwickau, Hauptbahnhof to Mainz, Römisches Theater via Leipzig Hbf and Frankfurt in around 5h 44m.