The train between Wetzlar and Essen takes 3h 12m. The train service runs several times per day from Wetzlar to Essen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Wetzlar and Essen. The earliest departure is at 6:18 AM in the morning, and the last departure from Wetzlar is at 6:18 PM which arrives into Essen at 9:30 PM. All services require a transfer, and take on average 3h 12m. The schedules shown below are for the next available departures.

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Want to know about travelling from Wetzlar to Essen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Wetzlar to Essen. However, there are services departing from Wetzlar station and arriving at Essen station via Dortmund Hbf. The journey, including transfers, takes approximately 3h 12m.
Wetzlar to Essen train services, operated by Deutsche Bahn Intercity (DB IC), depart from Wetzlar Bahnhof station.
Wetzlar to Essen train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Dortmund Hbf station.
Book your Wetzlar to Essen train tickets online with Deutsche Bahn Intercity (DB IC) and National Express.
The distance between Wetzlar and Essen is 144.3 km. The road distance is 222 km.
Deutsche Bahn Intercity (DB IC) operates a train from Wetzlar Bahnhof to Dortmund Hbf every 4 hours. Tickets cost €35–85 and the journey takes 2h 38m.