The train between Wetzlar and Essen takes 3h 32m. The train service runs several times per day from Wetzlar to Essen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Wetzlar and Essen. The earliest departure is at 7:26 AM in the morning, and the last departure from Wetzlar is at 9:26 PM which arrives into Essen at 12:58 AM. All services require a transfer, and take on average 3h 32m. The schedules shown below are for the next available departures.

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3h 32m • 1 changeWant to know about travelling from Wetzlar to Essen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Wetzlar to Essen. However, there are services departing from Wetzlar Bahnhof station and arriving at Essen Hbf station via Koblenz Hauptbahnhof station. The journey, including transfers, takes approximately 3h 32m.
Wetzlar to Essen train services, operated by Deutsche Bahn Regio (DB Regional), depart from Wetzlar Bahnhof station.
Wetzlar to Essen train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Essen Hbf station.
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The distance between Wetzlar and Essen is 144.3 km. The road distance is 187 km.
You can take a train from Wetzlar Bahnhof to Essen Hbf via Koblenz Hbf in around 4h 20m.