The average train between Wetzlar and Essen takes 4h 36m and the fastest train takes 3h 29m. The train service runs several times per day from Wetzlar to Essen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Wetzlar and Essen. The earliest departure is at 7:26 AM in the morning, and the last departure from Wetzlar is at 7:26 PM which arrives into Essen at 12:30 AM. All services require a transfer, and take on average 4h 36m. The schedules shown below are for the next available departures.

4h 48m • 1 change

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Arrives next day

5h 4m • 1 change

3h 29m • 1 change

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3h 29m • 1 change

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5h • 1 change

3h 29m • 1 change

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4h 55m • 1 change

5h • 1 change

3h 36m • 1 change

3h 29m • 1 change

4h 48m • 1 change

4h 32m • 1 change

3h 29m • 1 change

4h 48m • 1 change

4h 55m • 1 change

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3h 29m • 1 change

4h 48m • 1 change

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4h 48m • 1 change
Want to know about travelling from Wetzlar to Essen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Wetzlar to Essen. However, there are services departing from Wetzlar station and arriving at Essen station via Koblenz Hauptbahnhof. The journey, including transfers, takes approximately 4h 36m.
Wetzlar to Essen train services, operated by Deutsche Bahn Regio (DB Regional), depart from Wetzlar Bahnhof station.
Wetzlar to Essen train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Essen Hbf station.
Book your Wetzlar to Essen train tickets online with Deutsche Bahn Regio (DB Regional) and Deutsche Bahn Intercity (DB IC).
The distance between Wetzlar and Essen is 144.3 km. The road distance is 275 km.
You can take a train from Wetzlar Bahnhof to Essen Hbf via Koblenz Hbf in around 4h 20m.